Safety and antitumor activity of dostarlimab in patients with advanced or recurrent DNA mismatch repair deficient/microsatellite instability-high (dMMR/MSI-H) or proficient/stable (MMRp/MSS) endometrial cancer: interim results from GARNET—a phase I, sing… | Journal for ImmunoTherapy of Cancer
https://jitc.bmj.com/content/10/1/e003777
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Journal for ImmunoTherapy of Cancer
Safety and antitumor activity of dostarlimab in patients with advanced or recurrent DNA mismatch repair deficient/microsatellite…
Background Dostarlimab is a humanized monoclonal antibody that binds with high affinity to PD-1, resulting in inhibition of binding to PD-L1 and PD-L2. We report interim data from patients with endometrial cancer (EC) participating in a phase I trial of single…
Dostarlimab for the treatment of advanced endometrial cancer - PubMed
https://pubmed.ncbi.nlm.nih.gov/35184615/
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PubMed
Dostarlimab for the treatment of advanced endometrial cancer - PubMed
Although a randomized study has not yet been conducted, dostarlimab monotherapy should be the treatment of choice for patients with advanced MMRd EC in progression after a platinum-containing regimen. Selecting patients with EC for immune checkpoint inhibitors…
Jemperli (dostarlimab-gxly) to Treat Advanced Solid Tumours
https://www.clinicaltrialsarena.com/projects/jemperli-dostarlimab-gxly/
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Clinical Trials Arena
Jemperli (dostarlimab-gxly) for the Treatment of Advanced Solid Tumours, US
Jemperli (dostarlimab-gxly) is an anti-PD-1 antibody indicated to treat dMMR solid tumours and dMMR endometrial cancer in adults.
Belantamab mafodotin in combination with novel agents in relapsed/refractory multiple myeloma: DREAMM-5 study design | Future Oncology
https://www.futuremedicine.com/doi/10.2217/fon-2020-1269
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Future Oncology
Belantamab mafodotin in combination with novel agents in relapsed/refractory multiple myeloma: DREAMM-5 study design | Future Oncology
Belantamab mafodotin (belamaf) is a BCMA-targeted antibody–drug conjugate recently approved as monotherapy for adults with relapsed/refractory multiple myeloma who have received ≥4 prior therapies. Belamaf binds to BCMA and eliminates myeloma cells by multimodal…
💻 آخرین و به روزترین آموزشهای بیوانفورماتیک و بیولوژی محاسباتی و مقاله نویسی توسط دانشجویان دکتری تخصصی بیورانفوماتیک دانشگاه تهران
#R_programming
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#Statistical_analysis
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#Computational_genomics
#Computational_oncology
#Machine_learning
#Data_Science
#اخبار_بیوانفورماتیک
#نکات_آموزشی_بیوانفورماتیک
#پوزیشن_دکتری
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هم اکنون عضو شوید 👇👇👇
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#R_programming
#Python_programming
#MATLAB_programming
#Statistical_analysis
#Constraint_based_metabolic_networks_modeling
#Computational_genomics
#Computational_oncology
#Machine_learning
#Data_Science
#اخبار_بیوانفورماتیک
#نکات_آموزشی_بیوانفورماتیک
#پوزیشن_دکتری
#مقاله_نویسی
#تقویت_رزومه
هم اکنون عضو شوید 👇👇👇
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"Scientists Have Created Worms That Can Kill Cancer Cells" https://scitechdaily.com/scientists-have-created-worms-that-can-kill-cancer-cells/amp/
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SciTechDaily
Scientists Have Created Worms That Can Kill Cancer Cells
Osaka University researchers discovered that worms may be coated with hydrogel sheaths that contain useful cargo such as anti-cancer medications James Bond's famed quartermaster Q provided the secret agent with an unlimited supply of equipment and gadgets…
"How to find, read and organize papers" https://www.nature.com/articles/d41586-022-01878-7
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Humans Absorb Less Protein From Plant-Based Meat Than Normal Meat
https://scitechdaily.com/humans-absorb-less-protein-from-plant-based-meat-than-normal-meat/
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SciTechDaily
Humans Absorb Less Protein From Plant-Based Meat Than Normal Meat
Plant-based meat supplies less protein to human cells than chicken meat The push for plant-based meat has already gained a lot of support. However, it's not understood how much of the protein makes it into human cells, despite the fact that protein-rich plants…
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Learning Is Based on Neurons' Ability to Cooperate for Survival
https://neurosciencenews.com/metabolic-cooperation-learning-20964/
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Neuroscience News
Learning Is Based on Neurons’ Ability to Cooperate for Survival
Exploring systemwide intracellular metabolic cooperation as a mechanism for learning offers promise for a better understanding of how memory and learning occur in the brain.
New Molecule Discovered That Strongly Stimulates Hair Growth
https://scitechdaily.com/new-molecule-discovered-that-strongly-stimulates-hair-growth/amp/
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SciTechDaily
New Molecule Discovered That Strongly Stimulates Hair Growth
SCUBE3 has been found to be a potential therapeutic option for treating androgenetic alopecia. A signaling molecule known as SCUBE3, which was discovered by researchers at the University of California, Irvine, has the potential to cure androgenetic alopecia…
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Scientists discover hair growth signaling molecule SCUBE3 as potential baldness cure
https://www.notebookcheck.net/Scientists-discover-hair-growth-signaling-molecule-SCUBE3-as-potential-baldness-cure.640716.0.html
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Notebookcheck
Scientists discover hair growth signaling molecule SCUBE3 as potential baldness cure
The search for a cure of male or female alopecia in the form of significant hair loss has seen two major development in the span of just a few weeks. Researchers from the University of California, Irvine, have discovered the molecule that signals hair growth…
A wearable electrochemical biosensor for the monitoring of metabolites and nutrients
https://www.nature.com/articles/s41551-022-00916-z
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Nature
A wearable electrochemical biosensor for the monitoring of metabolites and nutrients
Nature Biomedical Engineering - A wearable electrochemical biosensor can continuously detect, in sweat during physical exercise and at rest, trace levels of multiple metabolites and nutrients,...
A Snake-Lover Built Robotic Legs For a Snake, and It's Insane
https://www.sciencealert.com/a-snake-lover-built-robotic-legs-for-a-snake-and-its-insane
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ScienceAlert
A Snake-Lover Built Robotic Legs For a Snake, And It's Insane
This is hilarious.
Metabolic scaling is the product of life-history optimization
https://www.science.org/doi/10.1126/science.abm7649
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Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial | Aging
https://www.aging-us.com/article/202188/text
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Aging-Us
Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial…
Aging | doi:10.18632/aging.202188. Yafit Hachmo, Amir Hadanny, Ramzia Abu Hamed, Malka Daniel-Kotovsky, Merav Catalogna, Gregory Fishlev, Erez Lang, Nir Polak, Keren Doenyas, Mony Friedman, Yonatan Zemel, Yair Bechor, Shai Efrati
Mechanical integrated circuit materials | Nature
https://www.nature.com/articles/s41586-022-05004-5
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Nature
Mechanical integrated circuit materials
Nature - A mechanical integrated circuit material based on Boolean mathematics and reconfigurable electrical circuits is created to demonstrate scalable information processing in synthetic,...
Researchers engineer novel material capable of ‘thinking’ | Penn State University
https://www.psu.edu/news/engineering/story/researchers-engineer-novel-material-capable-thinking/
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Scientists Grow “Synthetic” Embryo With Brain and Beating Heart – Without Eggs or Sperm
https://scitechdaily.com/scientists-grow-synthetic-embryo-with-brain-and-beating-heart-without-eggs-or-sperm/
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SciTechDaily
Scientists Grow “Synthetic” Embryo With Brain and Beating Heart – Without Eggs or Sperm
Scientists from the University of Cambridge have created model embryos from mouse stem cells that form a brain, a beating heart, and the foundations of all the other organs of the body. It represents a new avenue for recreating the first stages of life. The…