💉 How COVID unlocked the power of RNA vaccines

https://www.nature.com/articles/d41586-021-00019-w

📲Channel: @Bioinformatics

👨‍🏫 Bioinformatics workshop on sequence analysis

✍️ Registration Address:
https://forms.gle/k2A9a3xr73QxVxEAA

📆 Date: 23- 02- 2021
⏰Time: 10 AM to 12 noon

📲Channel: @Bioinformatics

📑 Cancer research needs a better map

Almost 15 years ago, scientists and clinicians set out to characterize genomes of tumours from thousands of patients. The result? The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC). Nearly every targeted cancer drug approved over the past decade has drawn from the data sets generated by these efforts. Study more...

📲Channel: @Bioinformatics

✍️ Common Biomarkers of apoptosis

Apoptosis refers to the physiological process of autonomous and orderly death of cells controlled by genes in order to maintain a stable environment in the body.... Clinical studies have shown that the inhibition of apoptosis is a hallmark of human cancer, and the ideal strategy for many targeted therapies is to specifically induce tumor cell death in vivo. Therefore, mechanism-based therapy in oncology can directly induce tumor cell apoptosis by targeting the molecular components of the apoptosis regulatory pathway, or indirectly induce apoptosis by regulating drug targets. Study more...

📲Channel: @Bioinformatics

🧑‍🏫 Online NGS Data Analysis Workshop

⏱ 1-4 February 2021 | 5:30 to 7:30 PM IST

📝 Register Here:
https://genespectrum.co.in/bioinformatics-training/ngs-data-analysis-with-galaxy/

📞 For more details contact on Whatsapp/Telegram: +91 7021386045

📲Channel: @Bioinformatics

👨‍🏫 Workshop on Drug design and development

✍️ Registration Link
https://decodelife.org/recent-training-workshop/
or you can scan the QR code to get registration link.

📔 Materials:
1. Linux on Window
2. Searching Chemical Space for Drug Designing
3. Protein Modeling and Analysis
4. Basics of Molecular Docking and Dynamics: Practical Considerations
5. Understanding molecular docking through practicals: Glide, Autodock and Gold
6. Understanding molecular docking and dynamics through practicals: AutoDock Vina and Desmond
7. Understanding molecular dynamics through practicals: AMBER

💲 Fees : Rupees 1000 For Indian Participant. / Dollar 20 (USA) for Foreign Participant.

📲Channel: @Bioinformatics

🎬 Genomic Analysis of SARS-COV-2: New Variants and the Vaccine

A discussion on the Selective Pressures, Biology and Genomics of SARS-COV-2. The focus of this discussion is on the epidemiology of SARS-COV-2 and how novel variants discussed in research literature and on mass media might play a role in the vaccine rollout around the world.
https://www.youtube.com/watch?v=XujRjFBRko0&feature=emb_logo

📲Channel: @Bioinformatics

📓 Why Use Epigenetic Analysis (Whitepaper)

Download the whitepaper from here

📲Channel: @Bioinformatics

Nine popular distance measures in Data Science

In computational biology, many algorithms, whether supervised or unsupervised, make use of distance measures. These measures, such as euclidean distance or cosine similarity, can often be found in algorithms such as k-NN, UMAP, HDBSCAN, etc.
Understanding the field of distance measures is more important than you might realize. Knowing when to use which distance measure can help you go from a poor classifier to an accurate model.

Study more here:
https://towardsdatascience.com/9-distance-measures-in-data-science-918109d069fa

📲Channel: @Bioinformatics

A rich collection of various SARS-CoV-2 (SARS2), SARS-CoV (SARS1), and MERS-CoV related datasets:
http://www.datjar.com:40090/h2v/

resulted from this research:
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-020-03935-2

📲Channel: @Bioinformatics

The next act for messenger RNA could be bigger than covid vaccines

https://www.technologyreview.com/2021/02/05/1017366/messenger-rna-vaccines-covid-hiv/

📲Channel: @Bioinformatics

💻 Machine learning generates realistic genomes for imaginary humans

https://phys.org/news/2021-02-machine-realistic-genomes-imaginary-humans.html

📲Channel: @Bioinformatics

😮 Opium use may have a preventive effect on getting infected with coronavirus

https://www.eurekaselect.com/node/182595/article/withdrawal-notice-the-relationship-between-opium-use-and-coronavirus-infection-a-brief-research-report-from-iran

📲Channel: @Bioinformatics

👨‍🏫 Registration is open for two week Cancer Genomics Workshop

✍️ Registration Link
https://decodelife.org

💲 Fees: Rupees 1000 For Indian Participant. / Dollar 20 (USA) for Foreign Participant.
We have kept nominal fees in order to ensure that only serious candidates participate.

💥Key Features :
▫️E- Certificate of participation
▫️Global Instructors
▫️Videos access for all sessions

📲Channel: @Bioinformatics

📊 4 reasons why we need better Mass Spec software

https://elucidata.io/4-reasons-why-we-need-better-mass-spec-software/

📲Channel: @Bioinformatics

🖥 Useful R programming video

https://www.youtube.com/watch?v=yBvOS91jIXI

📲Channel: @Bioinformatics

👨‍💻 Postdoc positions opened at the Barabasi Lab.

💥Position Summary
The lab of Professor Albert-László Barabási, together with the Network Science Institute at Northeastern University and the Division of Network Medicine at Harvard University, is looking for postdoctoral research associates in the area of biological networks, machine learning/AI, and science of science. The BarabasiLab's current work spans the applications of networks toward understanding human diseases, disease progression, biomarker discovery, and drug repurposing, as well as understanding the emergence of impact in art and science.

✅ Basic Qualifications
We are seeking motivated individuals with an interest in exploring complexity and its applications to medicine, food, art, science, and from a network perspective. The ideal candidate has a bioinformatics, physics, computer science, mathematics, or statistics Ph.D., and a working experience in network science/bioinformatics and ML/AI/DL.

✍️ Instructions‍:
https://www.barabasilab.com/jobs

📲Channel: @Bioinformatics

💊 Interesting paper for future Bioinformatics works

https://www.sanger.ac.uk/news_item/scientists-identify-over-140000-virus-species-in-the-human-gut-half-of-which-are-new-to-science/

📲Channel: @Bioinformatics

🧪 Re-evaluating experimental validation in the Big Data Era: a conceptual argument

Many researchers who work in fields such as bioinformatics and biomathematics, will have, at some point, come across the well-known query of whether they have ‘experimentally validated’ their results. This question, which is predominantly raised by people outside the computational field, is often asked with cynicism or at best suspicion towards results obtained from computational, mathematical or statistical models and more generally theoretical reasoning applied to empirical observations in an automated fashion.
Study more here:
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-021-02292-4

📲Channel: @Bioinformatics

📝 A detailed BLAST exercise with answers

✍️ Level: Introductory

🔹Exercise:
https://teaching.healthtech.dtu.dk/22111/index.php/Exercise:_BLAST
🔸Answers:
https://teaching.healthtech.dtu.dk/22111/index.php/ExBlast-Answers

In this exercise we will be using BLAST (Basic Local Alignment Search Tool) for searching sequence databases such as GenBank (DNA data) and UniProt (protein). When using BLAST for sequence searches it is of utmost importance to be able to critically evaluate the statistical significance of the results returned.
The BLAST software package is free to use (Open Source) and can be installed on any local system — it's originally written for UNIX type Operating Systems. The package contains both programs for performing the actual sequence searches against preexisting databases (e.g. "blastn" for DNA databases and "blastp" for protein databases), as well as a tool for creating new databases from scratch (the "fortmatdb" program).
In this exercise we will be using the Web-interface to BLAST hosted by the NCBI. For our purpose there are several advantages to this approach:
-We don't have to mess around with a UNIX command prompt.
-NCBI offers direct access to preformatted BLAST databases of all the data that they host:
▫️GenBank (+ derivates)
▫️Full Genome database
▫️Protein database (Both from translated GenBank and UniProt)
It should be noted that running BLAST locally (for example at the super-computer cluster at CBS/DTU) offers much more fine-grained control of DATA and workflow (everything can be noscripted/automated) than running BLAST through a web-interface.

📲Channel: @Bioinformatics

🧑‍🏫 Workshop on Advance Bioinformatics - NGS Data Analysis and Proteomics

⏱ Time: 1-5 March 2021 | 6:30 to 8:30 PM IST

📝 Registration link:
https://genespectrum.co.in/bioinformatics-training/ngs-proteomics-workshop/

📞 For more details contact on whatsapp/telegram : +91 7021386045

📲Channel: @Bioinformatics