GnRH agonists are the best way to achieve suppression of sex hormone production with no side effects, if you take the other sex hormone. The only problem is, this stuff costs about 150€/month. So naturally, health insurances are reluctant to cover it. In my country, they try to poison you with Cyproteronacetat instead because it's so damn cheap. CPA was developed as a cancer medication. It's a progestin and hence messes with your mental health, it fucks up your B12 intake, and it carries a proven risk of brain tumors that scales with life time dosage. So you want to take as little of it as you possibly can, for as short as possible. It's banned in the US, and not prescribed as trans* HRT in many other European countries anymore because of this. Mine is a little behind the times.
The other options are Spironolacton, which is a diuretic (it makes you piss a lot). The T-suppressing effects are weak at best. And Bicalutamid, which blocks the T-receptors instead. So it's hard to measure the effect and control the dosage. Scientific data on its effectiveness and risks are very limited. There have been cases of terminal liver damage.
It took me around half a year to get GnRHa covered. Absolutely worth it.
The other options are Spironolacton, which is a diuretic (it makes you piss a lot). The T-suppressing effects are weak at best. And Bicalutamid, which blocks the T-receptors instead. So it's hard to measure the effect and control the dosage. Scientific data on its effectiveness and risks are very limited. There have been cases of terminal liver damage.
It took me around half a year to get GnRHa covered. Absolutely worth it.
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There is a fifth, secret option to block T-production. If you overload the feedback system with so much estrogen that the hypothalamus gets confused, it will reduce GnRH output. It can't quite distinguish between T and E and thinks there is already way too much T in your body.
I've been using gel. At first it seemed my levels are high enough to achieve this effect. After a while however they stabilized at a level that was not sufficient to achieve T suppression without a blocker. My fallback plan was to get on E injections to reach those levels. A lot of people do. I was hesitant about too high E levels though. But this is just my gut feeling, not based on anything.
The sixth option is to just have your gonads surgically removed. Have your balls cut off.
I've been using gel. At first it seemed my levels are high enough to achieve this effect. After a while however they stabilized at a level that was not sufficient to achieve T suppression without a blocker. My fallback plan was to get on E injections to reach those levels. A lot of people do. I was hesitant about too high E levels though. But this is just my gut feeling, not based on anything.
The sixth option is to just have your gonads surgically removed. Have your balls cut off.
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If you want to know more, I can strongly recommend
https://transfemscience.org
https://transfemscience.org
Transfeminine Science
Transfeminine Science is a site for information on hormone therapy for transfeminine people.
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Bun's Lab
If you want to know more, I can strongly recommend https://transfemscience.org
There is virtually no funding for trans* health research. The evidence base is severely lacking, the studies that do exists are often flawed. In a lot of countries the health care options are limited and purposefully locked behind needless gatekeeping. As a result, many trans* people rely not only on self-medication but also the shared experiences of others that were desperate enough to experiment with their own bodies. Sites like the above are an essential part of the shared knowledge base we rely on.
Bun's Lab
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cfp.gulas.ch
Sound Chip, whisper me your secrets! 23rd Gulaschprogrammiernacht
Vintage sound chips make cool music, but what's hiding inside of them? Which algorithms are they using?
In the past years I've been dedicating my free time to building emulators for old digital sound chips from synthesizers/game consoles, in an effort…
In the past years I've been dedicating my free time to building emulators for old digital sound chips from synthesizers/game consoles, in an effort…
Oof. Caught a cough and a middle ear inflammation - on both sides. Been sick all week. Now on antibiotics.
I need to rant.
After more than a decade of lurking in this godforsaken place called Reddit, that has destroyed forum culture like the cancer that it is. That is nothing but a vehicle for advertisements, user profiling and data mining for AI training. I finally gave in and made an account. Just to make a long, well written post to ask for help to help a friend. Guess what happens next
After more than a decade of lurking in this godforsaken place called Reddit, that has destroyed forum culture like the cancer that it is. That is nothing but a vehicle for advertisements, user profiling and data mining for AI training. I finally gave in and made an account. Just to make a long, well written post to ask for help to help a friend. Guess what happens next
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