Original Article from The New England Journal of Medicine — Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy

Perception is utterly baffling. We can precisely describe the biological structure of eyes and brains. We can measure the electrochemical impulses and electrical fields generated by neurons. But reason ...

This randomized trial compares the effects of oral methotrexate, 25 mg weekly vs oral mycophenolate mofetil, 3 g daily, on measures of inflammation in patients with noninfectious uveitis.

Aims
Narrower retinal arterioles and wider retinal venules have been associated with macrovascular forms of cardiovascular disease (CVD). However, whether they are predictive of the development of h...

Training for physicians has a new name and a new focus. Abi Rimmer looks at what’s changed and why

Earlier this month the first cohort of junior doctors entered internal medical training (IMT), which replaces core medical training (CMT). Abi Rimmer spoke…

Purpose
To correct peripapillary retinal nerve fibre layer (pRNFL) measurements performed with spectral domain optical coherence tomography (SD‐OCT) for low image quality factor (QF) in patients wit...

This qualitative evaluation investigates the financial and environmental costs of unused pharmaceutical products after phacoemulsification surgery among US surgical sites.

This cohort study of claims from a national US insurer examines trends in and factors associated with rates of filled opioid prenoscriptions after incisional ocular surgeries.

An on-chip tunable photonic delay line is a key building block for applications including sensing, imaging, and optical communication. However, achieving long and tunable delay lines within a small...

Nature Communications - The use of PET for detection of Aβ in the brain in AD has limitations; studies also indicate that retinal changes, including Aβ deposition, occur in AD. Here the...

Myopic eyes have an increased risk of glaucoma. However, glaucomatous changes in a myopic eye are often difficult to detect. Classic structural and functional investigations to diagnose glaucoma may be confounded by myopia. Here, we identify some of the common…

Inhibitors of vascular endothelial growth factors are used to treat a myriad of retinal conditions, including exudative age-related macular degeneration (AMD), diabetic macular oedema (DME) and diabetic retinopathy. Although effective, long-term efficacy…

Aims International criteria for the diagnosis of ocular sarcoidosis (OS) was established by the first International Workshop on Ocular Sarcoidosis (IWOS) and validations studies revealed certain limitations of the criteria. To overcome the limitations, revised…

Aim To characterise combinations of multimodal imaging risk factors and predictive value for choroidal nevus transformation into melanoma.

Methods This is a retrospective review of multimodal imaging features for 3806 choroidal nevi from 1 January 2007 through…

Background/aims Dry eye disease (DED) is categorised by pathophysiology as aqueous deficient dry eye (ADDE), evaporative dry eye (EDE) or mixed. Treatment should be tailored to DED pathophysiology, but this is challenging to determine. This Delphi consultation…

Scientific Reports - Automatic choroidal segmentation in OCT images using supervised deep learning methods

Perceptions of training in gonioscopy

Accuracy of intraocular lens calculations based on fellow-eye biometry for phacovitrectomy for macula-off rhegmatogenous retinal detachments