Nature Communications - The use of PET for detection of Aβ in the brain in AD has limitations; studies also indicate that retinal changes, including Aβ deposition, occur in AD. Here the...

Myopic eyes have an increased risk of glaucoma. However, glaucomatous changes in a myopic eye are often difficult to detect. Classic structural and functional investigations to diagnose glaucoma may be confounded by myopia. Here, we identify some of the common…

Inhibitors of vascular endothelial growth factors are used to treat a myriad of retinal conditions, including exudative age-related macular degeneration (AMD), diabetic macular oedema (DME) and diabetic retinopathy. Although effective, long-term efficacy…

Aims International criteria for the diagnosis of ocular sarcoidosis (OS) was established by the first International Workshop on Ocular Sarcoidosis (IWOS) and validations studies revealed certain limitations of the criteria. To overcome the limitations, revised…

Aim To characterise combinations of multimodal imaging risk factors and predictive value for choroidal nevus transformation into melanoma.

Methods This is a retrospective review of multimodal imaging features for 3806 choroidal nevi from 1 January 2007 through…

Background/aims Dry eye disease (DED) is categorised by pathophysiology as aqueous deficient dry eye (ADDE), evaporative dry eye (EDE) or mixed. Treatment should be tailored to DED pathophysiology, but this is challenging to determine. This Delphi consultation…

Scientific Reports - Automatic choroidal segmentation in OCT images using supervised deep learning methods

Perceptions of training in gonioscopy

Accuracy of intraocular lens calculations based on fellow-eye biometry for phacovitrectomy for macula-off rhegmatogenous retinal detachments

When a person becomes infected with Toxoplasma gondii, ocular toxoplasmosis is the most common clinical presentation. The medical literature describes retinitis with surrounding hyperpigmentation secondary to proliferative changes in the retinal pigment epithelium…

Researchers have developed a new non-invasive optical imaging system that promises to improve diagnosis and treatments for dry eye disease. Dry eye, which often causes irritation and blurred vision, occurs ...

The “red reflex test” is used to screen children for leukocoria (“white eye”) in a standard pediatric examination, but is ineffective at detecting many eye disorders. Leukocoria also presents in casual photographs. The clinical utility of screening photographs…

Intravitreal injections and implants are used to deliver drugs to the retina because therapeutic levels of these medications cannot be provided by top…

At present at least 2.2 billion people around the world have a vision impairment, of whom at least 1 billion have a vision impairment that could have been prevented or is yet to be addressed. The world faces considerable challenges in terms of eye care, including…

Evaluation of an AI system for the automated detection of glaucoma from stereoscopic optic disc photographs: the European Optic Disc Assessment Study

This cross-sectional study compares the diagnostic accuracy of a smartphone-based artificial intelligence system vs ophthalmologist judgement in patients with referable diabetic retinopathy or any diabetic retinopathy in Mumbai, India.

Background Retinitis pigmentosa (RP) are a group of incurable and inherited eye conditions, and the leading cause of inherited blindness in people under the age of 60. The aim of this systematic review and meta-synthesis was to present a comprehensive overview…