The “red reflex test” is used to screen children for leukocoria (“white eye”) in a standard pediatric examination, but is ineffective at detecting many eye disorders. Leukocoria also presents in casual photographs. The clinical utility of screening photographs…

Intravitreal injections and implants are used to deliver drugs to the retina because therapeutic levels of these medications cannot be provided by top…

At present at least 2.2 billion people around the world have a vision impairment, of whom at least 1 billion have a vision impairment that could have been prevented or is yet to be addressed. The world faces considerable challenges in terms of eye care, including…

Evaluation of an AI system for the automated detection of glaucoma from stereoscopic optic disc photographs: the European Optic Disc Assessment Study

This cross-sectional study compares the diagnostic accuracy of a smartphone-based artificial intelligence system vs ophthalmologist judgement in patients with referable diabetic retinopathy or any diabetic retinopathy in Mumbai, India.

Background Retinitis pigmentosa (RP) are a group of incurable and inherited eye conditions, and the leading cause of inherited blindness in people under the age of 60. The aim of this systematic review and meta-synthesis was to present a comprehensive overview…

Background/Aims To compare the efficacy, anatomical outcomes and complications of intravitreal ranibizumab with those of laser photocoagulation for retinopathy of prematurity (ROP).

Methods This is a retrospective case series of 314 eyes from 165 infants…

Background To assess the outcomes of laser-assisted in situ keratomileusis (LASIK) performed for the treatment of myopia in terms of safety, efficacy and predictability in an 18-year clinical audit.

Method In this single-centre, prospective, non-randomised…

Eye - Introducing automated diabetic retinopathy systems: it’s not just about sensitivity and specificity

To evaluate panretinal photocoagulation (PRP) treatment and re-treatment patterns in patients with diabetic retinopathy (DR) and diabetic macular edem…

This randomized clinical trial evaluates the efficacy of administration of an adeno-associated virus vector designed to deliver a functional version of the CHM gene in patients with choroideremia.

To compare the effects of virtual reality headset wear and conventional desktop computer display use on ocular surface and tear film parameters.Twenty…

npj Aging - Daily blue-light exposure shortens lifespan and causes brain neurodegeneration in Drosophila