HEO has captured our 4,000th non-Earth image.
Building the world’s first in-orbit satellite inspection company began with hand-calculating ISS imaging opportunities and sifting frame by frame for a single capture. Today, our software automates the entire non-Earth imaging process, turning days of work into hundreds of captures every month.
The first image is our first successful verification non-Earth image and the second is a recent capture taken with our partner BlackSky Inc's satellite.
Source: @heospace
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A “Masterpiece” – For the First Time, Scientists Keep a Mammalian Cochlea Alive Outside the Body
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Shortly before his death in August 2025, A. James Hudspeth and his colleagues at The Rockefeller University’s Laboratory of Sensory Neuroscience accomplished a milestone that had never been reached before. They succeeded in keeping a small section of the cochlea alive and working outside the body, making it possible to study the organ’s function directly for the first time. Using a specially designed device, the team was able to track the cochlea’s extraordinary abilities in real time, including its fine-tuned sensitivity, precise frequency detection, and capacity to process a wide range of sound levels.Source: SciTechDaily
“We can now observe the first steps of the hearing process in a controlled way that was previously impossible,” says co-first author Francesco Gianoli, a postdoctoral fellow in the Hudspeth lab.
The achievement, detailed in two recent publications (in PNAS and Hearing Research, respectively), represents the culmination of Hudspeth’s fifty years of pioneering research into the cellular and neural basis of hearing. His work has continually pointed toward new possibilities for preventing and treating hearing loss.
Beyond its immediate applications, the advance also delivers long-sought experimental confirmation of a fundamental biophysical principle that underlies hearing across diverse species, a concept Hudspeth had pursued for more than twenty-five years.
“This study is a masterpiece,” says biophysicist Marcelo Magnasco, head of the Laboratory of Integrative Neuroscience at Rockefeller, who collaborated with Hudspeth on some of his seminal findings. “In the field of biophysics, it’s one of the most impressive experiments of the last five years.”
The mechanics of hearing
Though the cochlea is a marvel of evolutionary engineering, some of its fundamental mechanisms have long remained hidden. The organ’s fragility and inaccessibility—embedded as it is in the densest bone in the body—have made it difficult to study in action.
These challenges have long frustrated hearing researchers, because most hearing loss results from damage to sensory receptors called hair cells that line the cochlea. The organ has some 16,000 of these hair cells, so-called because each one is topped by a few hundred fine “feelers,” or stereocilia, that early microscopists likened to hair. Each bundle is a tuned machine that amplifies and converts sound vibrations into electrical responses that the brain can then interpret.
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SciTechDaily
A “Masterpiece” – For the First Time, Scientists Keep a Mammalian Cochlea Alive Outside the Body
Researchers have captured the living mechanics of hearing for the first time by sustaining a piece of cochlear tissue outside the body. Shortly before his death in August 2025, A. James Hudspeth and his colleagues at The Rockefeller University’s Laboratory…
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Why Laughter Is Contagious: Got The Giggles? Blame Evolution
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Sitting in the audience at a stand-up show; watching a comedy at the movies; at the office party when your boss breaks out their best knock-knock joke: these are all places where laughter is both encouraged and expected. During a quiet moment in church? Not so much. But wherever you are, if you hear someone else laughing, it’s likely you’ll get the urge to giggle too – however inappropriate that may be! Should we all just be able to control ourselves better, or is laughter really contagious?Source: IFLScience
The answer, in short, is yes.
“All emotions are contagious”
“Is laughter contagious? Well, actually, all emotions are contagious,” Dr Sandi Mann, chartered member of the British Psychological Society, told IFLScience. “We are designed to pick up other people’s emotions.”
It’s part of our evolution, and it’s something we share with other mammals. It’s been well established that apes – our closest relatives – laugh in a remarkably humanlike way. If you’re ever close enough to a bonobo to try tickling it (not something we’d necessarily recommend), you’ll find out.
Recent research even found that apes may have a sense of humor and love to tease each other. A 2021 review concluded that 65 different animal species show evidence of “play vocalizations” that mimic humans laughing when we’re having fun, mostly mammals but a few birds as well.
In fact, laughter is such a fundamental part of what it means to be human that it transcends language and culture – there’s not a single community of people on Earth that we know of who don’t laugh.
Why laughter is good for us
Part of the reason why a fit of the giggles spreads so easily, Dr Mann told us, is that shared emotions are integral to social bonding. A 2022 paper from University of Oxford Emeritus Professor of Evolutionary Psychology Robin Dunbar explored this further.
“I suggest that, when hominins needed to increase the size of their groups beyond the limit that could be bonded by grooming, they co-opted laughter […] as a form of chorusing to fill the gap,” Dunbar wrote.
Grooming – a social behavior we particularly associate with monkeys and apes, but which is seen throughout the animal world – boosts the production of endorphins in the brain. These chemical messengers relieve pain and generally make us feel good. Dunbar detailed some evidence that laughter has a similar effect, with the added benefit of being less intimate and time-consuming than grooming. Hence, humans laugh together all the time, but we’re rarely seen picking lice out of each other’s hair these days.
A hit of endorphins also helps us de-stress. When a group of people are sharing a tense situation, Dr Mann told IFLScience, humor can help to alleviate that as well as strengthen the bond between them: “Sometimes we just need to smile, laugh, have fun to relieve the stress.”
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IFLScience
Why Laughter Is Contagious: Got The Giggles? Blame Evolution
It’s something we share with other mammals.
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Scientists Find Brain Circuit That Locks Alcohol Users in Addiction Cycle
Source: SciTechDaily
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What drives a person to keep drinking alcohol despite the harm it causes to their health, relationships, and overall well-being? New research from Scripps Research points to a possible answer: a small midline brain region helps shape how animals learn to drink in order to relieve the stress and discomfort of withdrawal.
In a study recently published in Biological Psychiatry: Global Open Science, the Scripps Research team examined brain activity in the paraventricular nucleus of the thalamus (PVT) in rats. They discovered that when rats linked environmental cues with alcohol’s ability to ease withdrawal symptoms, activity in this brain region increased, reinforcing relapse behaviors.
By uncovering this pathway, the study highlights one of addiction’s most persistent aspects—using alcohol not for enjoyment but to avoid suffering—and may pave the way for new therapies for substance use disorders (SUDs) and related conditions such as anxiety.
“What makes addiction so hard to break is that people aren’t simply chasing a high,” says Friedbert Weiss, professor of neuroscience at Scripps Research and senior author of the study. “They’re also trying to get rid of powerful negative states, like the stress and anxiety of withdrawal. This work shows us which brain systems are responsible for locking in that kind of learning, and why it can make relapse so persistent.”
“This brain region just lit up in every rat that had gone through withdrawal-related learning,” says co-senior author Hermina Nedelescu of Scripps Research. “It shows us which circuits are recruited when the brain links alcohol with relief from stress—and that could be a game-changer in how we think about relapse.”
Source: SciTechDaily
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SciTechDaily
Scientists Find Brain Circuit That Locks Alcohol Users in Addiction Cycle
Scientists have pinpointed a hidden brain circuit that may explain why withdrawal drives people back to alcohol.
From a 20-Foot Poop Pile, Scientists Uncover the Secrets of Giant Sloths
Source: SciTechDaily
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Most people know sloths as slow-moving, bear-like creatures that dangle from trees, take nearly a month to digest a single meal, and defecate only once a week. Their closest relatives are anteaters and armadillos, which may sound like an unusual connection, but evolutionary history explains the link. Today only two sloth species exist, but in the past there were dozens, including one with a bottle-shaped snout specialized for eating ants and another that closely resembled early armadillos.
Many of these ancient sloths were far too large to live in trees. The giants of the group, belonging to the genus Megatherium, grew to the size of Asian bull elephants and weighed around 8,000 pounds [~3629kg].
“They looked like grizzly bears but five times larger,” said Rachel Narducci, collection manager of vertebrate paleontology at the Florida Museum of Natural History.
Narducci co-authored a study published in Science in which researchers examined ancient DNA and analyzed more than 400 fossils from 17 natural history museums to understand how and why some sloths reached such massive proportions.
Ground-dwelling sloths displayed an extraordinary range of body sizes. At one extreme was the enormous Megatherium, capable of stripping leaves from tall trees with its long, flexible tongue, serving as an ecological counterpart to giraffes. At the other was the comparatively smaller Shasta ground sloth, which thrived in the deserts of North America by feeding on cacti.
Tree-dwelling sloths, however, followed a different evolutionary path. Those that lived exclusively in the forest canopy have always been small, averaging about 14 pounds [~6.35kg]. Species that split their time between the ground and the trees were somewhat larger, weighing an average of 174 pounds [~79kg].
You don’t have to be a scientist to puzzle out why trees enforce a strict weight limit. It’s the same reason why modern tree sloths have a strange elastic quality to them: Branches break when put under too much strain, and sloths are not generally known for their ability to swiftly avert sudden disaster. Tree sloths have reportedly survived falls of up to 100 feet [~30m]. However, given that falls from even moderate heights can cause severe damage and some trees in the Amazon Rainforest top out at just under 300 feet [~91m], it makes evolutionary sense to be as small as possible when going out on a limb.
Why Did Ground Sloths Get So Big?
What’s less clear is why some ground sloths grew to such excessive sizes while others seemed content with being merely large. There may have been several reasons, which is why it’s been so hard for scientists to answer the question with confidence.
Larger sizes might have been advantageous for finding food or avoiding predators, for example. Ground sloths had a special fondness for caves, and their size undoubtedly played a role in their ability to find and make shelters. The moderately sized Shasta ground sloth favored small, natural caves bored by wind and water into the cliffsides of the Grand Canyon, like the alveoli of a gigantic, geologic lung. These also doubled as convenient latrines; in 1936, paleontologists discovered a mound of fossilized sloth poop, bat guano, and packrat middens more than 20 feet [~6m] thick in Rampart Cave, near Lake Mead.
Scientists analyzed ancient DNA and compared more than 400 fossils from 17 natural history museums to figure out how and why extinct sloths got so big.
Larger sloths weren’t restricted to pre-existing caves. Using claws that are among the largest of any known mammal, living or extinct, they could carve their own from bare earth and rock. Many of the caves they left behind are still around with claw-mark décor along the interior walls, evidence of their ancient nesting excavations.
Source: SciTechDaily
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SciTechDaily
From a 20-Foot Poop Pile, Scientists Uncover the Secrets of Giant Sloths
Sloths may seem like quirky tree-dwellers today, but their past reveals a dynasty of giants that once roamed the Americas. Most people know sloths as slow-moving, bear-like creatures that dangle from trees, take nearly a month to digest a single meal, and…
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Mushrooms Evolved Psychedelics Twice, and Scientists Just Found Out
Source: SciTechDaily
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This rare case of convergent evolution shows nature arriving at the same mind-altering molecule by two separate paths. The true reason fungi produce psilocybin remains unsolved, but theories range from predator defense to chemical communication. Beyond evolutionary intrigue, the discovery also offers new enzyme tools that could help produce psilocybin more efficiently for future medicines.
Ancient Molecule With a Modern Role
“This concerns the biosynthesis of a molecule that has a very long history with humans,” explains Prof. Dirk Hoffmeister, head of the research group Pharmaceutical Microbiology at Friedrich Schiller University Jena and the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI).
“We are referring to psilocybin, a substance found in so-called ‘magic mushrooms’, which our body converts into psilocin – a compound that can profoundly alter consciousness. However, psilocybin not only triggers psychedelic experiences, but is also considered a promising active compound in the treatment of therapy-resistant depression,” says Hoffmeister.
Two Evolutionary Paths to Psilocybin
The study, carried out within the Cluster of Excellence ‘Balance of the Microverse’, reveals that fungi developed the ability to produce psilocybin on at least two separate occasions in evolutionary history. Psilocybe mushrooms rely on a familiar set of enzymes to make the molecule, while fiber cap mushrooms use an entirely different biochemical toolkit. Despite these very different methods, both groups arrive at the same compound. Scientists call this convergent evolution, when unrelated species independently evolve the same trait.
Source: SciTechDaily
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SciTechDaily
Mushrooms Evolved Psychedelics Twice, and Scientists Just Found Out
Nature cracked the psilocybin code twice, and scientists are still puzzled why.
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Chronic Insomnia May Spark Changes in The Brain That Trigger Dementia
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Staring at the ceiling while the clock blinks 3am doesn't only sap energy for the next day. A large, long-running US study of older adults has now linked chronic insomnia to changes inside the brain that set the stage for dementia.Source: ScienceAlert
The researchers, from the Mayo Clinic in the US, followed 2,750 people aged 50 and over for an average of five and a half years. Every year the volunteers completed detailed memory tests and many also had brain scans that measured two telltale markers of future cognitive trouble: the buildup of amyloid plaques, and tiny spots of damage in the brain's white matter – known as white-matter hyperintensities.
Participants were classed as having chronic insomnia if their medical records contained at least two insomnia diagnoses a month apart – a definition that captured 16 percent of the sample.
Compared with people who slept soundly, those with chronic insomnia experienced a faster slide in memory and thinking and were 40 percent more likely to develop mild cognitive impairment or dementia over the study period.
When the team looked more closely, they saw that insomnia paired with shorter-than-usual sleep was especially harmful. These poor sleepers already performed as if they were four years older at the first assessment and showed higher levels of both amyloid plaques and white-matter damage.
By contrast, insomniacs who said they were sleeping more than usual, perhaps because their sleep problems had eased, had less white-matter damage than average.
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ScienceAlert
Chronic Insomnia May Spark Changes in The Brain That Trigger Dementia
The pattern is clear.
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Giant Stars With Black Holes Inside Them May Have Been Detected For The First Time
Source: ScienceAlert
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Some of the mysterious pinpricks of light at the dawn of the Universe could be a type of object we've never seen before.
According to a new analysis of a "little red dot" (LRD) nicknamed The Cliff, these unexplained objects could be supermassive black holes wrapped in huge, dense clouds of gas, like an atmosphere surrounding a stellar core.
It's a very tidy explanation that solves a problem astronomers are struggling to reconcile: a 'break' in the LRDs' light that makes galaxies in the early Universe seem older than possible.
"We … conclude that the rest-optical and near-infrared continuum of The Cliff cannot originate from a massive, evolved stellar population with an extremely high stellar density," writes a team led by astrophysicist Anna de Graaff of the Max Planck Institute for Astronomy in Germany.
"Instead, we argue that the most plausible model is that of a luminous ionising source reddened by dense, absorbing gas in its close vicinity. Currently, the only model capable of producing both the strength and shape of the observed Balmer break is that of a black hole star."
A Balmer break is a sharp change in the spectrum of an object in space occurring in the ultraviolet part of the spectrum, where shorter-wavelength light on one side of the line is much lower in intensity than the higher-wavelength light on the other side of the line. This feature is created by the absorption of shorter-wavelength light by hydrogen atoms.
A strong Balmer break is associated with galaxies that have a dominant population of A-type stars, which are just the right temperature to absorb light at the requisite wavelength.
Here's the kicker: to display that strong Balmer break, those galaxies have to be old enough for the earliest dominant population of O and B stars to have largely died off, leaving the A-type stars responsible for most of the galaxy's light, with little to no new star formation.
Many LRDs exhibit a strong Balmer break, at an epoch starting just 600 million years after the Big Bang, 13.8 billion years ago. Scientists believe this is too early in the lifespan of the Universe for a galaxy to have reached the stage of a dominant type-A population.
In turn, this has led to some investigation into what these small red lights at the dawn of spacetime might be – from primordial black holes to the seeds of supermassive stars.
Source: ScienceAlert
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ScienceAlert
Giant Stars With Black Holes Inside Them May Have Been Detected For The First Time
What ARE these things?
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In a World-First, Scientists Directly Observe Elusive “Dark Excitons”
Source: SciTechDaily
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For the first time, scientists in the Femtosecond Spectroscopy Unit at the Okinawa Institute of Science and Technology (OIST) have directly tracked how dark excitons evolve in atomically thin materials. This achievement paves the way for advances in both classical and quantum information technologies. The study was published in Nature Communications.
Professor Keshav Dani, who leads the unit, emphasized the importance of the work: “Dark excitons have great potential as information carriers, because they are inherently less likely to interact with light, and hence less prone to degradation of their quantum properties. However, this invisibility also makes them very challenging to study and manipulate. Building on a previous breakthrough at OIST in 2020, we have opened a route to the creation, observation, and manipulation of dark excitons.”
“In the general field of electronics, one manipulates electron charge to process information,” explains Xing Zhu, co-first author and PhD student in the unit. “In the field of spintronics, we exploit the spin of electrons to carry information. Going further, in valleytronics, the crystal structure of unique materials enables us to encode information into distinct momentum states of the electrons, known as valleys.”
The ability to use the valley dimension of dark excitons to carry information positions them as promising candidates for quantum technologies. Dark excitons are by nature more resistant to environmental factors like thermal background than the current generation of qubits, potentially requiring less extreme cooling and making them less prone to decoherence, where the unique quantum state breaks down.
Source: SciTechDaily
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SciTechDaily
In a World-First, Scientists Directly Observe Elusive “Dark Excitons”
Using one of the world’s most advanced spectroscopy systems, researchers have developed a framework to guide studies in next-generation quantum information technologies. For the first time, scientists in the Femtosecond Spectroscopy Unit at the Okinawa Institute…
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"Major Anomaly" As Interstellar Object 3I/Atlas Measured To Be Over 33 Billion Tons
Source: IFLScience
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A new study has attempted to pin down the properties of interstellar comet 3I/Atlas, finding it is "anomalously massive" at around 33 billion tons.
On July 1, 2025, astronomers spotted an object moving through the Solar System at nearly twice the velocity of previous interstellar visitors ‘Oumuamua and Comet Borisov. The object, which was confirmed to be an interstellar comet with its own dusty coma, and suspected to be far larger than the previous two, with a then-estimated nucleus (the rocky part of the comet, excluding its coma) of around 5.6 kilometers (3.5 miles).
Sizing comets is a tricky business, primarily because to do so, you need to distinguish the comet from its coma. As comets approach the Sun in their orbit and heat up, they outgas, losing gas and later (when they are even closer to the Sun) dust, which forms their distinctive trail or coma. This outgassing acts like a thruster, slightly altering the trajectory, rotation, and speed of the comet.
That can complicate measurements, but it can also provide key clues. In a new paper, which has not yet been peer reviewed, from Harvard's Richard Cloete, Avi Loeb, and Peter Vereš, the team looked at data compiled by the Minor Planet Center between May 15 and September 23, 2025, from 227 observatories around the world, and compared the object's trajectory to what we would expect from gravitational acceleration alone (i.e. acceleration caused by the Sun's mass as it approaches closer).
The team's paper found that the non-gravitational acceleration was pretty small, at below 15 meters per day squared. That's pretty tiny, considering that we have already seen significant outgassing by the comet, including using the JWST, with a mass loss rate of around 150 kilograms (330 pounds) per second. To this team crunching the numbers, that suggests that the object's nucleus is massive, resisting change to acceleration as the Sun-facing side outgasses.
The team estimates that the object weighs over 33 billion tons – or 33 trillion kilograms – with a nucleus diameter of 5 kilometers (3.1 miles). This is large for a comet, yes, but at 500 trillion tons, or 5×1017 kilograms (500 quadrillion kilograms), C/2014 UN271 (Bernardinelli-Bernstein) still has it beat. But then again, it has the largest comet nucleus ever seen at 128 kilometers (80 miles) across.
So, where is the anomaly? According to Loeb, the mystery is why we haven't spotted many more interstellar objects before we spotted one of this size.
"3I/ATLAS is more massive than the other two interstellar objects, 1I/Oumuamua and 2I/Borisov by 3–5 orders of magnitude, constituting a major anomaly," Loeb said in a blog post. "Given the limited reservoir of heavy elements, we should have discovered on the order of a hundred thousand interstellar objects on the 0.1-kilometer scale of 1I/Oumuamua before finding 3I/ATLAS, yet we only detected two interstellar objects previously."
Source: IFLScience
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IFLScience
"Major Anomaly" As Interstellar Object 3I/ATLAS Measured To Be Over 33 Billion Tons
Measuring the object's non-gravitational acceleration, the team believes they found something "anomalous".
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This Natural Compound Could Protect the Brain Against Stroke
Source: SciTechDaily
@EverythingScience
DMT, short for dimethyltryptamine, is a naturally occurring psychoactive compound that exists in a variety of plants and animals.
A recent study published in Science Advances by researchers at the HUN-REN BRC Institute of Biophysics and the Semmelweis University Heart and Vascular Centre reports that DMT can lessen the damaging impact of stroke in both laboratory cell cultures and animal models.
A solution from nature in the spotlight
This compound is also produced in the human brain, where it is now being investigated in clinical trials as a potential aid for restoring brain function following stroke. Until recently, the way DMT worked in this context remained unclear. “It is amazing how we can always turn to nature to find ingenious solutions for health problems,” says co-lead author Mária Deli from the HUN-REN BRC.
The blood-brain barrier as a therapeutic target
“We found that DMT significantly reduced infarct volume and edema formation in a rat stroke model,” explains co-first author Marcell László. In both animal experiments and cell culture models, the authors showed that DMT treatment restored the structure and function of the damaged blood-brain barrier and improved the function of astroglial cells.
This psychoactive compound also inhibited the production of inflammatory cytokines in brain endothelial cells and peripheral immune cells, while reducing the activation of brain microglia cells through Sigma-1 receptors.
DMT could serve as therapeutic adjuvant to existing stroke treatments
“The therapeutic options currently available for stroke are very limited. The dual action of DMT, protecting the blood-brain barrier while reducing brain inflammation, offers a novel, complex approach that could complement existing treatments,” says Judit Vigh, co-first author of the work.
Since current stroke therapies do not always result in full recovery, a DMT-based treatment may represent a promising new alternative, mainly in combination with existing methods. The recent findings from researchers in Szeged and Budapest, Hungary, support the development of a therapy that goes beyond the limitations of conventional stroke treatment. Clinical trials on the use of DMT and investigations on its long-term effects are currently ongoing.
Source: SciTechDaily
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SciTechDaily
This Natural Compound Could Protect the Brain Against Stroke
A natural compound present in the brain shows promise in reducing stroke damage by protecting the blood-brain barrier and lowering inflammation. DMT, short for dimethyltryptamine, is a naturally occurring psychoactive compound that exists in a variety of…
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30,000-year-old 'personal toolkit' found in the Czech Republic provides 'very rare' glimpse into the life of a Stone Age hunter-gatherer
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Around 30,000 years ago, a hunter-gatherer left behind what may be a "personal toolkit" in what is now the Czech Republic, a new study finds.Source: Live Science
Researchers uncovered the extraordinary cluster of artifacts in 2021 during an excavation at the Paleolithic site of Milovice IV. The "kit" contains 29 stone blades and bladelets that were found clumped together. The nature of the find indicates that the tools were bundled when deposited, likely in a container or case made from a perishable material, according to the study, which was published Aug. 13 in the Journal of Paleolithic Archaeology.
The find provides a remarkable glimpse into the life of a hunter-gatherer from the Paleolithic, which spans roughly 3.3 million years ago to just over 10,000 years ago.
The artifacts likely highlight an episode in the life of one person — which is "very rare" for the Paleolithic, study first author Dominik Chlachula, a researcher at the Institute of Archaeology of the Czech Academy of Sciences, told Live Science in an email.
Moreover, the discovery may shed light on the behavior of prehistoric people during migrations or hunting trips, which did not tend to leave behind many traces in the landscape and are therefore practically invisible to archaeologists, he said.
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Live Science
30,000-year-old 'personal toolkit' found in the Czech Republic provides 'very rare' glimpse into the life of a Stone Age hunter…
Archaeologists have found an extraordinary cluster of Stone Age artifacts that may have been the personal gear of a single prehistoric individual.
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'Groundbreaking' gene therapy is first treatment for Huntington's disease to slow the condition
Source: Live Science
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In a groundbreaking first, a gene therapy in clinical trials has slowed the progression of Huntington's disease, a rare genetic disorder in which toxic bits of protein cause brain cells to malfunction and die.
To date, approved treatments for Huntington's disease aim to manage its symptoms, which most often emerge in a person's 30s or 40s. The progressive condition injures and kills key neurons involved in controlling mood, cognition and motor control. Various drugs can help to offset the depression, hallucinations and poorly coordinated movements that arise from that destruction.
Now, in trial results shared Wednesday (Sept. 24), scientists announced that a new gene therapy called AMT-130 appears to slow the disease's progression — marking a first for the field.
"These groundbreaking data are the most convincing evidence in the field to date and underscore the disease-modifying effect in Huntington's disease, where an urgent need persists," Dr. Sarah Tabrizi, the lead scientific advisor on the trial and the director of the University College London (UCL) Huntington's Disease Centre, said in a statement. "For patients, AMT-130 has the potential to preserve daily function, keep them in work longer, and meaningfully slow disease progression."
Source: Live Science
@EverythingScience
Live Science
'Groundbreaking' gene therapy is first treatment for Huntington's disease to slow the condition
Results from a three-year trial suggest an experimental gene therapy for Huntington's disease can slow the progression of the deadly condition by 75%.
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Don't rule out the grasshopper mouse. These rodents are equipped with special venom-blocking proteins that are especially useful when battling a potentially paralyzing foe—like the giant hairy scorpion.
Source: @NatGeo
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The first animals on Earth may have been sea sponges, chemical fossils suggest
Source: Phys.org
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A team of MIT geochemists has unearthed new evidence in very old rocks suggesting that some of the first animals on Earth were likely ancestors of the modern sea sponge.
In a study appearing in the Proceedings of the National Academy of Sciences, the researchers report that they have identified "chemical fossils" that may have been left by ancient sponges in rocks that are more than 541 million years old. A chemical fossil is a remnant of a biomolecule that originated from a living organism that has since been buried, transformed, and preserved in sediment, sometimes for hundreds of millions of years.
The newly identified chemical fossils are special types of steranes, which are the geologically stable form of sterols, such as cholesterol, that are found in the cell membranes of complex organisms. The researchers traced these special steranes to a class of sea sponges known as demosponges. Today, demosponges come in a huge variety of sizes and colors, and live throughout the oceans as soft and squishy filter feeders. Their ancient counterparts may have shared similar characteristics.
"We don't know exactly what these organisms would have looked like back then, but they absolutely would have lived in the ocean, they would have been soft-bodied, and we presume they didn't have a silica skeleton," says Roger Summons, the Schlumberger Professor of Geobiology Emeritus in MIT's Department of Earth, Atmospheric and Planetary Sciences (EAPS).
The group's discovery of sponge-specific chemical fossils offers strong evidence that the ancestors of demosponges were among the first animals to evolve, and that they likely did so much earlier than the rest of Earth's major animal groups.
Source: Phys.org
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phys.org
The first animals on Earth may have been sea sponges, chemical fossils suggest
A team of MIT geochemists has unearthed new evidence in very old rocks suggesting that some of the first animals on Earth were likely ancestors of the modern sea sponge.
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It may look like these comets are racing, but they are not. Comets C/2025 K1 ATLAS (left) and C/2025 R2 SWAN (right) appeared near each other by chance last week in the featured image taken from France's Reunion Island in the southern Indian Ocean.
Fainter Comet ATLAS is approaching our Sun and will reach its closest approach in early October when it is also expected to be its brightest -- although still only likely visible with long exposures on a camera. The brighter comet, nicknamed SWAN25B, is now headed away from our Sun, although its closest approach to Earth is expected in mid-October, when optimistic estimates have it becoming bright enough to see with the unaided eye. Each comet has a greenish coma of expelled gas and an ion tail pointing away from the Sun.
Image Credit & Copyright: Luc Perrot (TWAN)
Source: @apod
@EverythingScience
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Whenever you see the ISS from Earth, WE aboard the ISS cannot see you!
When ISS is exposed in sunlight, our window reflectivity blinds us! We can only see you when you cannot see us!
Same effect as how you cannot see through your kitchen window at night when the lights are on!
Source: RT @astro_Pettit
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Scientists Found a Major Problem With Vitamin B12 Guidelines, and Your Brain Might Be at Risk
Source: SciTechDaily
@EverythingScience
Meeting the standard daily requirement for vitamin B12, which is essential for making DNA, red blood cells, and nerve tissue, may not provide enough protection for the brain, particularly in older adults. In fact, falling within the “normal” range could still increase the risk of cognitive problems.
Researchers at UC San Francisco studied healthy older adults and discovered that participants with lower B12 levels, even though still considered normal, showed neurological and cognitive weaknesses. These individuals had more damage in the brain’s white matter (the network of nerve fibers that allows different regions of the brain to communicate) and scored lower on tests measuring cognitive speed and visual processing compared with those who had higher B12 levels. The study was published in Annals of Neurology.
Rethinking Vitamin B12 Guidelines
According to senior author Ari J. Green, MD, of UCSF’s Departments of Neurology and Ophthalmology and the Weill Institute for Neurosciences, the results raise concerns about whether current B12 recommendations are sufficient and suggest that guidelines may need to be revised.
“Previous studies that defined healthy amounts of B12 may have missed subtle functional manifestations of high or low levels that can affect people without causing overt symptoms,” said Green, noting that clear deficiencies of the vitamin are commonly associated with a type of anemia. “Revisiting the definition of B12 deficiency to incorporate functional biomarkers could lead to earlier intervention and prevention of cognitive decline.”
Source: SciTechDaily
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SciTechDaily
Scientists Found a Major Problem With Vitamin B12 Guidelines, and Your Brain Might Be at Risk
Low-normal B12 in older adults was tied to slower processing, cognitive decline, and brain damage. Scientists warn current requirements may be too low.
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“Very Strange” – Saturn’s Moon Titan Is Behaving Unusually
Source: SciTechDaily
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Researchers at the University of Bristol have uncovered unusual behavior in Titan’s atmosphere for the first time.
Using data from the Cassini-Huygens mission, a collaboration between NASA, the European Space Agency (ESA), and the Italian Space Agency, the team found that Saturn’s largest moon has a dense, hazy atmosphere that does not rotate in step with the surface. Instead, it oscillates like a gyroscope, shifting position with the change of seasons.
Titan stands out as the only moon in the Solar System with a substantial atmosphere, a feature that has fascinated planetary scientists for decades. After analyzing 13 years of thermal infrared measurements collected by Cassini, the researchers were able to chart how Titan’s atmosphere leans and drifts over time.
A gyroscopic wobble
“The behavior of Titan’s atmospheric tilt is very strange!” said Lucy Wright, lead author and postdoctoral researcher at Bristol’s School of Earth Sciences. “Titan’s atmosphere appears to be acting like a gyroscope, stabilizing itself in space.
“We think some event in the past may have knocked the atmosphere off its spin axis, causing it to wobble.
“Even more intriguingly, we’ve found that the size of this tilt changes with Titan’s seasons.”
Source: SciTechDaily
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SciTechDaily
“Very Strange” – Saturn’s Moon Titan Is Behaving Unusually
Titan’s atmosphere tilts and shifts seasonally. The discovery shapes future exploration. Researchers at the University of Bristol have uncovered unusual behavior in Titan’s atmosphere for the first time. Using data from the Cassini-Huygens mission, a collaboration…
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New Research Identifies Moonquake Dangers That Could Threaten Future Lunar Missions
Source: SciTechDaily
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A recent study found that ground shaking caused by moonquakes, not meteorite impacts, was responsible for altering the terrain in the Taurus-Littrow valley, the site of the Apollo 17 landing in 1972. The research also identified a likely source of these surface changes and evaluated the potential hazards by applying new seismic models, with results that carry important implications for both future lunar exploration and the development of permanent bases on the Moon.
Geological evidence from Apollo 17 site
The research team examined data from the Apollo 17 site, where astronauts had gathered rock samples from boulder falls and landslides believed to have been triggered by moonquakes. By analyzing these geological traces, they were able to estimate the intensity of past moonquakes and determine their most likely origin.
“We don’t have the sort of strong motion instruments that can measure seismic activity on the moon like we do on Earth, so we had to look for other ways to evaluate how much ground motion there may have been, like boulder falls and landslides that get mobilized by these seismic events,” Schmerr said.
Source: SciTechDaily
@EverythingScience
SciTechDaily
New Research Identifies Moonquake Dangers That Could Threaten Future Lunar Missions
A new study reveals that seismic activity on the Moon may threaten the stability of future long-term infrastructure. A recent study found that ground shaking caused by moonquakes, not meteorite impacts, was responsible for altering the terrain in the Taurus…
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Gaia telescope discovers our galaxy's great wave
@EverythingScience
Our Milky Way galaxy never sits still: it rotates and wobbles. And now, data from the European Space Agency's Gaia space telescope reveal that our galaxy also has a giant wave rippling outwards from its center.Source: Phys.org
We've known for about a hundred years that the galaxy's stars rotate around its center, and Gaia has measured their speeds and motions. Since the 1950s, we've known that the Milky Way's disk is warped. Then, in 2020, Gaia discovered that this disk wobbles over time, similarly to the motion of a spinning top.
And now it has become clear that a great wave stirs the motion of stars in our galaxy over distances of tens of thousands of light-years from the sun. Like a rock thrown into a pond, making waves ripple outwards, this galactic wave of stars spans a large portion of the Milky Way's outer disk.
@EverythingScience
phys.org
Gaia telescope discovers our galaxy's great wave
Our Milky Way galaxy never sits still: it rotates and wobbles. And now, data from the European Space Agency's Gaia space telescope reveal that our galaxy also has a giant wave rippling outwards from its ...
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