Research Project:
What I currently do is to apply expansion microscope (EXM)into virology, none have done it before. I want to use an optical microscope to look at a single virus particle.
So far, none can do this. I aim to publish in Nature.
Long story short, EXM is simply to expand your sample to achieve magnification comparable to transmission electron microscope(TEM).
Although it sounds easy, there are some obstacles:
1.The agent to expand your sample (I tackled)
2.How to expand evenly without affecting the relative molecule geometry
3.Signal fades after expansion
For more, plz read this paper
What I currently do is to apply expansion microscope (EXM)into virology, none have done it before. I want to use an optical microscope to look at a single virus particle.
So far, none can do this. I aim to publish in Nature.
Long story short, EXM is simply to expand your sample to achieve magnification comparable to transmission electron microscope(TEM).
Although it sounds easy, there are some obstacles:
1.The agent to expand your sample (I tackled)
2.How to expand evenly without affecting the relative molecule geometry
3.Signal fades after expansion
For more, plz read this paper
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