Alterations in glutamate and the experience of ego dissolution with psilocybin
“ higher levels of medial prefrontal cortical glutamate were associated with negatively experienced ego dissolution, lower levels in hippocampal glutamate were associated with positively experienced ego dissolution. Such findings provide further insights into the underlying neurobiological mechanisms of the psychedelic, as well as the baseline, state. Importantly, they may also provide a neurochemical basis for therapeutic effects as witnessed in ongoing clinical trials. “
NatureArticle,
“ higher levels of medial prefrontal cortical glutamate were associated with negatively experienced ego dissolution, lower levels in hippocampal glutamate were associated with positively experienced ego dissolution. Such findings provide further insights into the underlying neurobiological mechanisms of the psychedelic, as well as the baseline, state. Importantly, they may also provide a neurochemical basis for therapeutic effects as witnessed in ongoing clinical trials. “
NatureArticle,
Forwarded from Integral Life +
Why we have so many problems with our teeth
Antiseptic mouthwashes kill the bacteria that cause cavities, but they also kill beneficial strains that have evolved to keep harmful bacteria in check.
Inspired by recent innovations in microbiome therapies, researchers are beginning to focus on remodeling the dental plaque community. Oral probiotics, targeted antimicrobials and microbiota transplants are on the horizon.
Article,
Antiseptic mouthwashes kill the bacteria that cause cavities, but they also kill beneficial strains that have evolved to keep harmful bacteria in check.
Inspired by recent innovations in microbiome therapies, researchers are beginning to focus on remodeling the dental plaque community. Oral probiotics, targeted antimicrobials and microbiota transplants are on the horizon.
Article,
Scientific American
Why We Have So Many Problems with Our Teeth
Our choppers are crowded, crooked and riddled with cavities. It hasn’t always been this way
👍1
How Many People Did It Take to Build the Great Pyramid?
Article
Article
IEEE Spectrum
How Many People Did it Take to Build the Great Pyramid?
Not nearly as many as old estimates would have you believe. Here is a back-of-the-envelope calculation, based on simple physics
Relationship between psychedelics, the brain, well-being, and creativity
Article,
Article,
satori
Mysterious Drugs that (Re)train Your Mind
Remarkable relationship between psychedelics, the brain, well-being, and creativity
1,700-Year-Old Board Game Found in Norwegian Burial Mound
Article
Article
Life in Norway
Archaeologists Find Roman Iron Age Board Game in Norway
Rare elongated dice and board game pieces from the Roman Iron Age have been discovered in western Norway. Last month, Norwegian archaeologists chose to excavate the remains of a small Early Iron Age grave cairn
Forwarded from Corpse World Monologues
An Elder was asked by a solider would God forgive a sinner. He replied to him: If your cloak is torn, will you throw it away? The soldier replied: No. I will mend it and put it back on. The elder replied: If you take care of your cloak, will God not be merciful to His own image?
Blood of recovered Covid-19 patients is becoming a hot commodity
Article
Article
WSJ
Blood of Recovered Covid-19 Patients Is Becoming a Hot Commodity
Companies that make antibody tests that are seen as key to easing lockdowns say high prices for the blood of recovered Covid-19 patients pose a hurdle to developing the tests.
Black Hole Paradoxes Reveal a Fundamental Link Between Energy and Order
Article
Article
Quanta Magazine
Black Hole Paradoxes Reveal a Fundamental Link Between Energy and Order
By chewing on the problems posed by “extremal” black holes, physicists have exposed a surprising and universal connection between energy and entropy.
Humpbacks bounce back from near extinction to help fight climate change
Article
Article
The Sydney Morning Herald
Superheroes of the deep: humpbacks bounce back from near extinction to help fight climate change
Australia's humpback whale population is bouncing back from near extinction with 40,000 expected off the Australian east coast this breeding season, while helping the world fight climate change.