Stuff I Liked
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221920/
The short list according to a HN user:
- Optimize diet: minimize simple CHO, minimize inflammation. - Patients given choice of several low glycemic, low inflammatory, low grain diets.
- Enhance autophagy, ketogenesis - Fast 12 hr each night, including 3 hr prior to bedtime.
- Reduce stress - Personalized—yoga or meditation or music, etc.
- Optimize sleep - 8 hr sleep per night; melatonin 0.5mg po qhs; Trp 500mg po 3x/wk if awakening. Exclude sleep apnea.
- Exercise - 30-60′ per day, 4-6 days/wk
- Brain stimulation - Posit or related
- Homocysteine <7 - Me-B12, MTHF, P5P; TMG if necessary
- Serum B12 >500 - Me-B12
- CRP <1.0; A/G >1.5 - Anti-inflammatory diet; curcumin; DHA/EPA; optimize hygiene
- Fasting insulin <7; HgbA1c <5.5 - Diet as above
- Hormone balance - Optimize fT3, fT4, E2, T, progesterone, pregnenolone, cortisol
- GI health - Repair if needed; prebiotics and probiotics
- Reduction of A-beta - Curcumin, Ashwagandha
- Cognitive enhancement - Bacopa monniera, MgT
- 25OH-D3 = 50-100ng/ml - Vitamins D3, K2
- Increase NGF - H. erinaceus or ALCAR
- Provide synaptic structural components - Citicoline, DHA
- Optimize antioxidants - Mixed tocopherols and tocotrienols, Se, blueberries, NAC, ascorbate, α-lipoic acid
- Optimize Zn:fCu ratio - Depends on values obtained
- Ensure nocturnal oxygenation - Exclude or treat sleep apnea
- Optimize mitochondrial function - CoQ or ubiquinol, α-lipoic acid, PQQ, NAC, ALCAR, Se, Zn, resveratrol, ascorbate, thiamine
- Increase focus - Pantothenic acid
- Increase SirT1 function - Resveratrol
- Exclude heavy metal toxicity - Evaluate Hg, Pb, Cd; chelate if indicated
- MCT effects - Coconut oil or Axona
- Optimize diet: minimize simple CHO, minimize inflammation. - Patients given choice of several low glycemic, low inflammatory, low grain diets.
- Enhance autophagy, ketogenesis - Fast 12 hr each night, including 3 hr prior to bedtime.
- Reduce stress - Personalized—yoga or meditation or music, etc.
- Optimize sleep - 8 hr sleep per night; melatonin 0.5mg po qhs; Trp 500mg po 3x/wk if awakening. Exclude sleep apnea.
- Exercise - 30-60′ per day, 4-6 days/wk
- Brain stimulation - Posit or related
- Homocysteine <7 - Me-B12, MTHF, P5P; TMG if necessary
- Serum B12 >500 - Me-B12
- CRP <1.0; A/G >1.5 - Anti-inflammatory diet; curcumin; DHA/EPA; optimize hygiene
- Fasting insulin <7; HgbA1c <5.5 - Diet as above
- Hormone balance - Optimize fT3, fT4, E2, T, progesterone, pregnenolone, cortisol
- GI health - Repair if needed; prebiotics and probiotics
- Reduction of A-beta - Curcumin, Ashwagandha
- Cognitive enhancement - Bacopa monniera, MgT
- 25OH-D3 = 50-100ng/ml - Vitamins D3, K2
- Increase NGF - H. erinaceus or ALCAR
- Provide synaptic structural components - Citicoline, DHA
- Optimize antioxidants - Mixed tocopherols and tocotrienols, Se, blueberries, NAC, ascorbate, α-lipoic acid
- Optimize Zn:fCu ratio - Depends on values obtained
- Ensure nocturnal oxygenation - Exclude or treat sleep apnea
- Optimize mitochondrial function - CoQ or ubiquinol, α-lipoic acid, PQQ, NAC, ALCAR, Se, Zn, resveratrol, ascorbate, thiamine
- Increase focus - Pantothenic acid
- Increase SirT1 function - Resveratrol
- Exclude heavy metal toxicity - Evaluate Hg, Pb, Cd; chelate if indicated
- MCT effects - Coconut oil or Axona