Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism"
—the 1st human to undergo custom genome editing
—outgrowth of decades of NIH funded research.

Paper.

Agents from scratch

This repo covers the basics of building agents:
+ Fundamentals
+ Build an agent
+ Agent eval
+ Agent w/ human-in-the-loop
+ Agent w/ long-term memory
Code (all open source).

Building agents -Combing workflow (router) with agent that can call email tools.
Notebook.
Slides.

Agent evals -Unit tests (Pytest) for triage decision + tools calls (test structured outputs using heuristic eval) and LLM-as-judge to eval email responses
Notebook.
Slides.

Human-in-the-loop -Add human in the loop for approval / editing of specific tool calls.
Notebook.

Memory - Add memory, so the agent learned email response preferences from human feedback
Notebook.

Agent can be hooked into Gmail by swapping out the tools used. Components are also general and can be used w/ various tools / MCP servers.

Qwen introduced Parallel Scaling Law for Language Models

"We introduce the third and more inference-efficient scaling paradigm: increasing the model’s parallel computation during both training and inference time."

"We draw inspiration from classifier-free guidance (CFG)".

"In this paper, we hypothesize that the effectiveness of CFG lies in its double computation."

"We propose a proof-of-concept scaling approach called parallel scaling (PARSCALE) to validate this hypothesis on language models. "

"parallelizing into P streams equates to scaling the model parameters by O(log P)".

"for a 1.6B model, when scaling to P = 8 using PARSCALE, it uses 22× less memory increase and 6× less latency increase compared to parameter scaling that achieves the same model capacity".

GitHub

OpenAI introduced AI agent codex.

it is a software engineering agent that runs in the cloud and does tasks for you, like writing a new feature of fixing a bug.

U can run many tasks in parallel. Starting to roll out today to ChatGPT pro, enterprise, and team users.

Arc is hiring a Chief Scientific Officer!

We think is the most dynamic and ambitious biology research organization in the world.

They want to build the world's first virtual cell + use it to develop cures to complex diseases like Alzheimer's.

IBM has released report the Agentic AI in Financial Services

highlights

1. AI agents enable a paradigm shift from responsive to adaptive technology services, creating more accessible, personalised #banking services & experiences for customers.

2. Organisations must adopt a measured, phased approach balancing #innovation with comprehensive risk management, through thorough assessments, clear governance structures, talent development, & continuous monitoring.

3. Successfully managing agentic AI requires seamless cooperation across business functions, supported by transparent governance structures and communication channels.

4. Understanding where new risks emerge and implementing appropriate controls is essential, recognising agentic AI as a fundamentally different technological paradigm requiring new approaches to #governance & controls.

5. Early integration of #compliance considerations validates use cases before significant investment while ensuring alignment with organisational risk appetite.

6. Organisations must develop holistic AI literacy programs—including philosophy, linguistics, law, and anthropology—to formulate and responsible #AIstrategies and address potential model biases.

The UK tax authority has announced that, starting from January 1, 2026, crypto asset companies operating in the UK must comprehensively report user and transaction data, including user identity, address, tax identification number, and details of each transaction, in compliance with the global Crypto Asset Reporting Framework (CARF) to combat tax evasion and enhance transparency.

Violators will face a maximum fine of £300 per user.

Adobe introduced HUMOTO, 4D dataset for human-object interaction, developed with a combination of wearable motion capture, SOTA 6D pose estimation vision models, LLM, and the professional refining works of multiple animation studios.

HUMOTO features:
1. Over 700 diverse daily activities
2. Interactions with 60+ objects, 70+ articulated parts.
3. Fine-grained text annotations
4. Detailed hand and finger movements.

Microsoft introduced Magentic-UI — an experimental human-centered web agent

It automates your web tasks while keeping you in control —through co-planning, co-tasking, action guards, and plan learning.

Fully open-source.

Google is launching their own coding agent, Jules, at I/O today

It lets you make changes to your GitHub repos with English prompts in a VM using Gemini 2.5 Pro. It's Google’s version of Devin.

Here's the leaked official repo of prompts it can do.

ByteDance presents the Pre-trained Model Averaging strategy, a novel framework for model merging during LLM pre-training.

Found that merging checkpoints trained with constant learning rates not only achieves significant performance improvements but also enables accurate prediction of annealing behavior.

Code might be posted there

Claude 4 is here ! Anthropic Prepares to Launch Claude 4

The lineup will reportedly include 2 versions:

1. Claude Sonnet 4 - a faster version for everyday tasks.

2. Claude Opus 4 - a powerful model for complex problems and creative work.

Based on leaked information, these models are currently in a closed testing environment marked "not intended for production use" and subject to strict rate limitations.

Several intriguing features have been discovered in the configuration files:

"show_raw_thinking" / "show_raw_thinking_mechanism" - functionality that potentially allows users to observe the AI's thought formation process.

The models appear to operate in an environment based on a popular web framework.

A sophisticated "feature gates" system is being employed to precisely control which capabilities are available to different users.

Configuration includes specific parameters for various interaction methods and model performance metrics.

The technical JSON contains numerous rule sets and session parameters suggesting enhanced personalization capabilities.

Google DeepMind introduced Gemma 3n, a model that runs on as little as 2GB of RAM

It shares the same architecture as Gemini Nano, and is engineered for incredible performance. Researchers added audio understanding, so now it’s multimodal, fast and lean, and runs on-device (no cloud connection required!).

Coming soon: AI avatars in Google Vids

Just write a noscript and choose an avatar to deliver your message. It’s a fast, consistent way to create polished video content — for onboarding, announcements, product explainers, and more.

Agents at home. Mistral released Devstral, a SOTA open model designed specifically for coding agents and developed with All hands AI.

P-1 A shared the first paper: "On the Evaluation of Engineering AGI"

A paradigm shift has occurred in the AI field over the past year - the focus shifted from algorithms to ever more complex and diverse evals and RL environments

Together with domain experts researchers've developed in-house an "equivalent" of SWE-Bench but for design engineers who work at industrial oems of the world.

They informally call it the "Archie IQ" eval.

They developed a rich taxonomy of evaluation questions spanning from methodological knowledge to real-world design problems and est Archie on very complex design workflows, that encompass design synthesis, evaluation, etc.

Apple introduced EgoDex the largest and most diverse dataset of dexterous human manipulation to date — 829 hours of egocentric video + paired 3D hand poses across 194 tasks.

Unlike teleoperation, egocentric video is passively scalable - like text and images on the Internet.

Researchers use Apple Vision Pro to collect video + precise pose annotations (unlike Ego4D, which lacks native pose data). This unlocks 5x the scale of existing large datasets like DROID.

Also propose new benchmarks and train imitation learning policies for dexterous trajectory prediction. Below are 30 Hz wrist and fingertip trajectories on the test set, where blue = ground truth, red = model predictions, and points get lighter up to 2 seconds in the future.

The full dataset is now publicly available to the community, access details are in the paper. Sample code for data loading is coming soon.

Anthropic is hosting an event tomorrow at 9:30 am PT.

Elon Musk's xAI announced Live Search in the API

The new beta (free for a limited time) feature allows apps leveraging Grok models to search real-time info from X and the internet, including news.

Here's how easy it is to try out Grok 3's new live search:

1/ Grab a key from xAI
2/ Remix our template
3/ Add your API key to Secrets
4/ Click Run and start chatting with Grok.

Since it's built with Agent, you can remix and keep editing with Agent.

Here's the template to get started.

Tencent presented Hunyuan-TurboS

- Hybrid Transformer-Mamba MoE (56B active params) trained on 16T tokens
- Dynamically switching between rapid responses and deep ”thinking” modes
- Overall top 7 on LMSYS Chatbot Arena.

VanEck will launch a private digital assets fund in June 2025 focused on the Avalanche ecosystem.

The fund will invest in projects with long-term token utility around the TGE stage across sectors such as gaming, financial services, payments, and AI, while allocating idle capital to Avalanche-native RWA products to maintain onchain liquidity.