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Noooo Theresa Tam Noooo!
“The Delta variant is a formidable beast. It’s .. it’s a virus that is very highly transmissible. F̶o̶r̶t̶u̶n̶a̶t̶e̶l̶y̶ ̶t̶h̶e̶ ̶v̶a̶c̶c̶i̶n̶e̶ ̶i̶s̶ ̶s̶t̶i̶l̶l̶ ̶v̶e̶r̶y̶ ̶e̶f̶f̶e̶c̶t̶i̶v̶e̶ ̶a̶g̶a̶i̶n̶s̶t̶ ̶t̶h̶e̶ ̶D̶e̶l̶t̶a̶ ̶v̶a̶r̶i̶a̶n̶t̶,̶ ̶i̶n̶c̶l̶u̶d̶i̶n̶g̶,̶ ̶e̶h̶h̶ ̶.̶.̶ ̶m̶o̶s̶t̶l̶y̶,̶ ̶p̶a̶r̶t̶i̶c̶u̶l̶a̶r̶l̶y̶ ̶a̶g̶a̶i̶n̶s̶t̶ ̶t̶h̶e̶ ̶s̶e̶v̶e̶r̶e̶ ̶o̶u̶t̶c̶o̶m̶e̶s̶ ̶s̶u̶c̶h̶ ̶a̶s̶ ̶h̶o̶s̶p̶i̶t̶a̶l̶i̶z̶a̶t̶i̶o̶n̶ ̶a̶n̶d̶ ̶d̶e̶a̶t̶h̶,̶ ̶w̶h̶i̶c̶h̶ ̶i̶s̶ ̶g̶r̶e̶a̶t̶ ̶n̶e̶w̶s̶.̶ But we’ve also have learned that the vaccines are not perfect in terms of reducing infections, and whether it’s mild or asymptomatic infections, and that vaccinated individuals, although they’re at reduced risk of getting infection, could get infected and when they do get infected they actually could have, uhmm .. similar viral loads to those who are unvaccinated. [.]"
“The Delta variant is a formidable beast. It’s .. it’s a virus that is very highly transmissible. F̶o̶r̶t̶u̶n̶a̶t̶e̶l̶y̶ ̶t̶h̶e̶ ̶v̶a̶c̶c̶i̶n̶e̶ ̶i̶s̶ ̶s̶t̶i̶l̶l̶ ̶v̶e̶r̶y̶ ̶e̶f̶f̶e̶c̶t̶i̶v̶e̶ ̶a̶g̶a̶i̶n̶s̶t̶ ̶t̶h̶e̶ ̶D̶e̶l̶t̶a̶ ̶v̶a̶r̶i̶a̶n̶t̶,̶ ̶i̶n̶c̶l̶u̶d̶i̶n̶g̶,̶ ̶e̶h̶h̶ ̶.̶.̶ ̶m̶o̶s̶t̶l̶y̶,̶ ̶p̶a̶r̶t̶i̶c̶u̶l̶a̶r̶l̶y̶ ̶a̶g̶a̶i̶n̶s̶t̶ ̶t̶h̶e̶ ̶s̶e̶v̶e̶r̶e̶ ̶o̶u̶t̶c̶o̶m̶e̶s̶ ̶s̶u̶c̶h̶ ̶a̶s̶ ̶h̶o̶s̶p̶i̶t̶a̶l̶i̶z̶a̶t̶i̶o̶n̶ ̶a̶n̶d̶ ̶d̶e̶a̶t̶h̶,̶ ̶w̶h̶i̶c̶h̶ ̶i̶s̶ ̶g̶r̶e̶a̶t̶ ̶n̶e̶w̶s̶.̶ But we’ve also have learned that the vaccines are not perfect in terms of reducing infections, and whether it’s mild or asymptomatic infections, and that vaccinated individuals, although they’re at reduced risk of getting infection, could get infected and when they do get infected they actually could have, uhmm .. similar viral loads to those who are unvaccinated. [.]"
Trevor Bedford (Nextstrain, GISAID, Gates Foundation Peasant) has written a Damage-Control-Nonsense-Thread pseudo-investigating the question whether "Non Sterilizing (Leaky) Transfections" are creating more Variants within the Transfected Group:
As expected, due to his massive Conflicts of Interests his conclusion in that crap-thread is: "Noooo Muuuh Nooo!" - Nothing else was to be expected from one of the "High Priests of Immunomythology with a Blue Check Mark".
Prior to that embarassing thread, he had debunked himself with his own data, clearly showing how the introduction of the "Non Sterilizing Transfection" initiated rapid phylogenetic branching at exactly the RBD domain of the Spike Protein (S1 Subunit).
Now Bedford has been thoroughly debunked by Jonathan J. Couey in his Twitch (starts at Minute 37:00):
https://www.twitch.tv/videos/1215043422
Bedford's Nonsense-Thread:
https://twitter.com/trvrb/status/1462816217794695170
Bedford debunks himself:
https://www.youtube.com/watch?v=VErVD_H1BZ0
As expected, due to his massive Conflicts of Interests his conclusion in that crap-thread is: "Noooo Muuuh Nooo!" - Nothing else was to be expected from one of the "High Priests of Immunomythology with a Blue Check Mark".
Prior to that embarassing thread, he had debunked himself with his own data, clearly showing how the introduction of the "Non Sterilizing Transfection" initiated rapid phylogenetic branching at exactly the RBD domain of the Spike Protein (S1 Subunit).
Now Bedford has been thoroughly debunked by Jonathan J. Couey in his Twitch (starts at Minute 37:00):
https://www.twitch.tv/videos/1215043422
Bedford's Nonsense-Thread:
https://twitter.com/trvrb/status/1462816217794695170
Bedford debunks himself:
https://www.youtube.com/watch?v=VErVD_H1BZ0
Japan:
⇢ Low hospitalisations, low mortality, high vax rate (70%, more options, not only mRNA), high IVM uptake ( statistically not known yet), very low PCR testing-rate (dropped to minus -80%)
⇢ SARS CoV-2 has become fully endemic, low evolutionary pressure on S1, especially at the Receptor Binding Domain (RBD)
⇢ Indicates holistic treatment approach
⇢ Tokyo Medical Association Chairman Haruo Ozaki recommends IVM to all C19 Patients: https://archive.ph/GDJr0 (August 2021)
⇢ Japan Data: https://toyokeizai.net/sp/visual/tko/covid19/en.html
⇢ Treatment:
https://perma.cc/79V3-J8UU
⇢ Japan doesn't throw MDs in jail or strips licences for prescribing, like in Pfizer-bribed Western nations. If MDs prescribe it or patients want it as prophylactic, they are allowed to; IVM included in the clinical study:
http://jja-contents.wdc-jp.com/pdf/JJA74/74-1-open/74-1_44-95.pdf
⇢ Japan = host country of IVM discovery - avermectin in japanese soil:
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3043740/
⇢ Low hospitalisations, low mortality, high vax rate (70%, more options, not only mRNA), high IVM uptake ( statistically not known yet), very low PCR testing-rate (dropped to minus -80%)
⇢ SARS CoV-2 has become fully endemic, low evolutionary pressure on S1, especially at the Receptor Binding Domain (RBD)
⇢ Indicates holistic treatment approach
⇢ Tokyo Medical Association Chairman Haruo Ozaki recommends IVM to all C19 Patients: https://archive.ph/GDJr0 (August 2021)
⇢ Japan Data: https://toyokeizai.net/sp/visual/tko/covid19/en.html
⇢ Treatment:
https://perma.cc/79V3-J8UU
⇢ Japan doesn't throw MDs in jail or strips licences for prescribing, like in Pfizer-bribed Western nations. If MDs prescribe it or patients want it as prophylactic, they are allowed to; IVM included in the clinical study:
http://jja-contents.wdc-jp.com/pdf/JJA74/74-1-open/74-1_44-95.pdf
⇢ Japan = host country of IVM discovery - avermectin in japanese soil:
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3043740/
The Austrian Minister for Health - Wolfgang Mückstein - is turning into Frankenstein by the day. Is it the outdated 2020 Spike in the 3rd "Booster"?
https://twitter.com/Bobby_Network/status/1463933101848018955
https://twitter.com/Bobby_Network/status/1463933101848018955
ezgif-7-7a224705e641.gif
13.4 MB
Austrian Future Visions 2022 in GIF Format (Uncensored):
The Austrian executive implements Wolfgang Mueckstein's (Minister of "Health"["Security"]) & Alexander Schallenberg's (unelected Prime Minister) strict orders, tries to force-'booster' so-called transfection hesitant (or mRNA-Transfection-SpikeOnlyFocusShitShow-Sceptics).
Full (Unredacted) BigFail Collection:
https://bit.ly/30WbEWm
https://bit.ly/3nxr1Nl
The Austrian executive implements Wolfgang Mueckstein's (Minister of "Health"["Security"]) & Alexander Schallenberg's (unelected Prime Minister) strict orders, tries to force-'booster' so-called transfection hesitant (or mRNA-Transfection-SpikeOnlyFocusShitShow-Sceptics).
Full (Unredacted) BigFail Collection:
https://bit.ly/30WbEWm
https://bit.ly/3nxr1Nl
Preperations are being made for winter.
Github-"Issue" #343:
"B.1.1 decendant associated with Southern Africa with high number of Spike mutations #343" (B.1.1.529)
Countries circulating: Botswana (3 genomes), Hong Kong ex S. Africa (1 genome, partial)
Denoscription:
Conserved Spike mutations - A67V, Δ69-70, T95I, G142D/Δ143-145, Δ211/L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493K, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F
Conserved non-Spike mutations - NSP3 – K38R, V1069I, Δ1265/L1266I, A1892T; NSP4 – T492I; NSP5 – P132H; NSP6 – Δ105-107, A189V; NSP12 – P323L; NSP14 – I42V; E – T9I; M – D3G, Q19E, A63T; N – P13L, Δ31-33, R203K, G204R
Have an insider view into a bioinformatician's world, feat. FearPr0n Modelers like Georg Roemer (Nextstrain, CoVariant), Rambout:
https://github.com/cov-lineages/pango-designation/issues/343
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspic
Github-"Issue" #343:
"B.1.1 decendant associated with Southern Africa with high number of Spike mutations #343" (B.1.1.529)
Countries circulating: Botswana (3 genomes), Hong Kong ex S. Africa (1 genome, partial)
Denoscription:
Conserved Spike mutations - A67V, Δ69-70, T95I, G142D/Δ143-145, Δ211/L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493K, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F
Conserved non-Spike mutations - NSP3 – K38R, V1069I, Δ1265/L1266I, A1892T; NSP4 – T492I; NSP5 – P132H; NSP6 – Δ105-107, A189V; NSP12 – P323L; NSP14 – I42V; E – T9I; M – D3G, Q19E, A63T; N – P13L, Δ31-33, R203K, G204R
Have an insider view into a bioinformatician's world, feat. FearPr0n Modelers like Georg Roemer (Nextstrain, CoVariant), Rambout:
https://github.com/cov-lineages/pango-designation/issues/343
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspic
"Differences in Vaccine and SARS-CoV-2 Replication Derived mRNA: Implications for Cell Biology and Future Disease
Kevin McKernan, Anthony M. Kyriakopoulos, Peter McCullough
Codon optimization describes the process used to increase protein production by use of alternative but synonymous codon changes. In SARS-CoV-2 mRNA vaccines codon optimizations can result in differential secondary conformations that inevitably affect a protein’s function with significant consequences to the cell. Importantly, when codon optimization increases the GC content of synthetic mRNAs, there can be an inevitable enrichment of G-quartets which potentially form G-quadruplex structures. The emerging G-quadruplexes are favorable binding sites of RNA binding proteins like helicases that inevitably affect epigenetic reprogramming of the cell by altering trannoscription, translation and replication. In this study, we performed a RNA fold analysis to investigate alterations in secondary structures of mRNAs inSARS-CoV-2 vaccines due to codon optimization. We show a significant increase in the GC content of mRNAs in vaccines as compared to native SARS-CoV-2 RNA sequences encoding the spike protein. As the GC enrichment leads to more G-quadruplex structure formations, these may contribute to potential pathological processes initiated by SARS-CoV-2 molecular vaccination."
https://osf.io/bcsa6/
https://anandamide.substack.com/p/differences-in-vaccine-and-sars-cov
Kevin McKernan, Anthony M. Kyriakopoulos, Peter McCullough
Codon optimization describes the process used to increase protein production by use of alternative but synonymous codon changes. In SARS-CoV-2 mRNA vaccines codon optimizations can result in differential secondary conformations that inevitably affect a protein’s function with significant consequences to the cell. Importantly, when codon optimization increases the GC content of synthetic mRNAs, there can be an inevitable enrichment of G-quartets which potentially form G-quadruplex structures. The emerging G-quadruplexes are favorable binding sites of RNA binding proteins like helicases that inevitably affect epigenetic reprogramming of the cell by altering trannoscription, translation and replication. In this study, we performed a RNA fold analysis to investigate alterations in secondary structures of mRNAs inSARS-CoV-2 vaccines due to codon optimization. We show a significant increase in the GC content of mRNAs in vaccines as compared to native SARS-CoV-2 RNA sequences encoding the spike protein. As the GC enrichment leads to more G-quadruplex structure formations, these may contribute to potential pathological processes initiated by SARS-CoV-2 molecular vaccination."
https://osf.io/bcsa6/
https://anandamide.substack.com/p/differences-in-vaccine-and-sars-cov
Differences in Vaccine and SARS-CoV-2 Replication Derived mRNA: Implications for Cell Biology and Future Disease
Kevin McKernan, Anthony M. Kyriakopoulos, Peter McCullough
In a nutshell:
⇢"muuh, Codon Optimization is N1-Methylpseudouridine (abbreviated m1Ψ), not Pseudouridine (Ψ) muuh"
⇢in silico analysis: it also alters mRNA secondary structures in vaccines, result: quadruplex formation
"The use of N1-methylpseudouridine in these mRNAs will further complicate the folding predictions as N1-methylpseudouridine (m1Ψ) has promiscuousbase pairing with G and A and is known to create errors in translation. These m1Ψ replacements are excellent for evading host RNAses but they are also implicated in Toll Like Receptor biology and this is something unique to mRNA vaccines.
[.] This has been described as 'reprogramming the innate immune and adaptive immune response'. [.]"
https://osf.io/bcsa6/
https://anandamide.substack.com/p/differences-in-vaccine-and-sars-cov
Kevin McKernan, Anthony M. Kyriakopoulos, Peter McCullough
In a nutshell:
⇢"muuh, Codon Optimization is N1-Methylpseudouridine (abbreviated m1Ψ), not Pseudouridine (Ψ) muuh"
⇢in silico analysis: it also alters mRNA secondary structures in vaccines, result: quadruplex formation
"The use of N1-methylpseudouridine in these mRNAs will further complicate the folding predictions as N1-methylpseudouridine (m1Ψ) has promiscuousbase pairing with G and A and is known to create errors in translation. These m1Ψ replacements are excellent for evading host RNAses but they are also implicated in Toll Like Receptor biology and this is something unique to mRNA vaccines.
[.] This has been described as 'reprogramming the innate immune and adaptive immune response'. [.]"
https://osf.io/bcsa6/
https://anandamide.substack.com/p/differences-in-vaccine-and-sars-cov