An impressive number of transformations in both compilers and in ordinary programming are special cases of a transformation called “defunctionalization.” This post explains what it is a…

An open letter against Apple's new privacy-invasive client-side content scanning. - nadimkobeissi/appleprivacyletter

AlphaFold2 and related systems use deep learning to predict protein structure from co-evolutionary relationships encoded in multiple sequence alignments (MSAs). Despite dramatic, recent increases in accuracy, three challenges remain: (i) prediction of orphan…

Earlier this week I released sqlite-utils 3.14 with a powerful new command-line tool: sqlite-utils convert, which applies a conversion function to data stored in a SQLite column. Anyone who works …

Browse the latest Computer Science papers in Arxiv, and hear their Abstracts like a podcast.

A big report by the world’s scientists will predict global temperatures could rise beyond 1.5 degrees by early next decade, far earlier than expected.

Academics, activists and amateurs are making imaginative use of powerful tools

The relentlessness of chronic pain wears you down. Beyond being a physical distraction in and of itself, it disrupts sleep, interferes with work and relationships, and can even alter the way we process emotions by causing physiological changes in

A newly formed patent troll is looking for big money from small business websites, just for using free, off-the-shelf login verification tools. Defenders of the American Dream, LLC (DAD ), is sending

Biden’s major bipartisan infrastructure plan struck a rare chord of cooperation between Republicans and Democrats, but changes it proposes to cryptocurrency regulation are tripping up the bill.

Before I launch into the ergonomics and math stuff, imagine that you’re at a movie theater. If you sit in the front section of the theater, it’s hard to see the whole screen without twisting your neck from side to side. These seats are always the last to…

Human evolution favors energy conservation, but has our evolution worked against us since inactivity — sitting — is linked to health risks? A new study of a modern hunter-gatherer society finds that they lack health risks for heart disease and metabolic disease…

Welcome! This is going to be the first of a new sort of post we’ll do from time to time where I answer a number of shorter questions posed by my patrons over at Patreon who are at the Patres …

A very long time ago I had an interesting if flawed idea. The idea was to (optionally) replace instances of expression constructs with equations defining or referring to components of conventional …

A mystery solved by science: a new type of giant clam in the Indian Ocean, unmasked!