Capital efficiency for pros, leverage for bettors, rich yields for market makers, and a dangerous failure mode.

Yue, Luo, and colleagues discovered that adenosine signalling is the common underlying mechanism of rapid acting antidepressant therapies, unifying the effects of ketamine, ECT and acute intermittent hypoxia. They use genetically encoded sensors, along with…

YouTube is now using AI to alter people's videos without permission. (There are threads about this at https://mastodon.content.town/@operationpuppet/115640694705318541 & https://mastodon.nzoss.nz/@strypey/115598837629003478 etc)

This is really disturbing…

A minimal pastebin for code snippets

For every cloud service I use, I want to have a local copy of my data for backup purposes and independence. Unfortunately, the gphotos-sync tool stopped working in March 2025 when Google restricted the OAuth scopes, so I needed an alternative for my existing…

This article explores three data models for strings with few distinct values: a simple string, a lookup table or an enum type.

reverse engineering a $200 commercial protection system, only to discover they protected the installer instead of the software. the crack is copying files.

The Simpsons Search Engine - Create Memes and GIFs

The missing standard library for multithreading in JavaScript (Works in the browser, Node.js, Deno, Bun) - W4G1/multithreading

Check if your license plate has been searched in the Flock mass surveillance database. Search public audit logs from police departments across the country.

Fast, focused, and open — a modern WebKit browser for Mac.

Google is 'looking into' a devastating Gmail attack that locks users out of their accounts with no way to recover.

Let’s continue our marvelous trip into GUI Wonderland, where we’ll learn 80s computing alongside our trusty Apple Lisa, the first personal computer with a GUI!

Dmitry.GR: PalmOS on new hardware!

Watch now: History of The Graphical User Interface (GUI): A Wonderful Curse https://youtu.be/fHMPGhezj0s?si=DuBg3tOL_hiEG7sY

This video is a TV show made about the software Ivan Sutherland developed in his 1963 thesis at MIT's Lincoln Labs, "Sketchpad, A…

The European Commission has accused X of misleadingly authenticating user accounts with blue ticks, withholding data from researchers and not transparently signposting advertisements.

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Merch - https://jellyfishmachine.myspreadshop.com/
Let's make ourselves a tiny little model airplane engine! The engine is 0.1cc (.006 ci) displacement and we will explore two different types of fuel.
Thanks to Richard Gordon for the designing the engine…

Wolfram releases the Wolfram Compute Services system--a fully programmable, streamlined way to scale up Wolfram Language computations. For large volumes of data, extensive iterations, large-scale parallelism and more.

Low-res camera fun.

We have finally finished the Chinese release which we started 2 years ago. We look at all the work involved.