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Hacker News
Use of Bayesian methodology in clinical trials of drug and biological products [pdf]
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How I learned everything I know about programming
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Hacker News
OpenBSD-current now runs as guest under Apple Hypervisor
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U.S. carbon pollution rose in 2025, a reversal from prior years
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NBC News
U.S. carbon pollution rose last year. Experts blame a cold winter, natural gas prices and data centers.
Whereas U.S. emissions fell in prior years, the country spewed 2.4% more heat-trapping gases from fossil fuels in 2025 than in the year before, according to new research.
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Show HN: Gambit, an open-source agent harness for building reliable AI agents
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GitHub
GitHub - bolt-foundry/gambit: Agent harness framework for building, running, and verifying LLM workflows
Agent harness framework for building, running, and verifying LLM workflows - bolt-foundry/gambit
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SETI Home Flags 100 Signals After Sorting 12B Others
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Berkeley News
For 21 years, enthusiasts used their home computers to search for ET. UC Berkeley scientists are homing in on 100 signals they…
UC Berkeley’s SETI@home, one of the most popular crowd-sourced research projects ever, turned up some 12 billion signals of interest. A lengthy analysis found 100 worth another look.
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My Gripes with Prolog
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Buttondown
My Gripes with Prolog
It's not my favorite language
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Hacker News
Americans Overwhelmingly Support Science, but Some Think the U.S. Is Lagging
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Scientific American
Americans Overwhelmingly Support Science, but Some Think the U.S. Is Lagging Behind: Pew
A new report finds that a majority of Americans think the U.S. should be a world leader in science, but Democrats increasingly believe other countries are catching up
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Boeing knew of flaw in part linked to UPS plane crash
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Bbc
Boeing knew of flaw in part linked to UPS plane crash, US safety board report says
An aircraft that crashed in November had a structural flaw that had been identified by Boeing 15 years ago, investigators say.
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All 23-Bit Still Lifes Are Glider Constructible
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Mitchell Is Typing
All 23-Bit Still Lifes Are Glider Constructible
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What a Programmer Does (1967) [pdf]
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San Francisco to offer free childcare to people making up to $230k
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the Guardian
San Francisco to make childcare free for families earning up to $230,000
Officials to offer 50% subsidy up to $310,000 in effort to make one of world’s most expensive cities more affordable
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List of individual trees
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Cloudflare threatens Italy exit over €14M fine
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IO+
Cloudflare threatens Italy exit over €14M fine
A €14 million fine has sparked a showdown, with Cloudflare threatening to exit Italy—revealing Europe’s fragile digital infrastructure.
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I Built a 1 Petabyte Server from Scratch [video]
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YouTube
I Built a 1 Petabyte Server From Scratch
I build a petabyte / 45 disk capable NAS / JBOD from the ground up starting with custom sheet metal, 3d printed parts, and custom electronics. If you’ve seen another petabyte build on the internet, then this video will show you more of the low level internals…
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Ask HN: What are your best purchases under $100?
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Show HN: Reversing YouTube’s “Most Replayed” Graph
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Priyavrat Misra
Reversing YouTube's "Most Replayed" Graph
An interactive exploration of the engineering behind YouTube's 'Most Replayed' graph.
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Hacker News
On Being a Human Being in the Time of Collapse (2022) [pdf]
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AI Destroys Institutions
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Ssrn
How AI Destroys Institutions
Civic institutions—the rule of law, universities, and a free press—are the backbone of democratic life. They are the mechanisms through which complex societies
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Interactive eBPF
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Hacker News
Just the Browser
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Just the Browser
Just the Browser - Just the Browser
Remove AI features, telemetry data reporting, sponsored content, product integrations, and other annoyances from web browsers.
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