what if moderating corticotropin can help with memory under/after stress?
https://www.jneurosci.org/content/early/2025/05/30/JNEUROSCI.2146-24.2025
https://www.jneurosci.org/content/early/2025/05/30/JNEUROSCI.2146-24.2025
Journal of Neuroscience
Role of Hypothalamic CRH Neurons in Regulating the Impact of Stress on Memory and Sleep
Stress profoundly affects sleep and memory processes. Stress impairs memory consolidation and, similarly, disruptions in sleep compromise memory functions. Yet, the neural circuits underlying stress-induced sleep and memory disturbances are still not fully…
as macos users now often have various juicy stuff like crypto wallets etc, macos viruses are evolving /sigh/
https://www.sentinelone.com/labs/macos-nimdoor-dprk-threat-actors-target-web3-and-crypto-platforms-with-nim-based-malware/
https://www.sentinelone.com/labs/macos-nimdoor-dprk-threat-actors-target-web3-and-crypto-platforms-with-nim-based-malware/
SentinelOne
macOS NimDoor | DPRK Threat Actors Target Web3 and Crypto Platforms with Nim-Based Malware
NimDoor reflects a leap in DPRK’s offensive toolkit, mixing compile-time trickery with native noscripting to complicate and deter analysis.
in Spain, cops think if you use google pixel you must be a drug dealer
https://www.androidauthority.com/google-pixel-organized-crime-preferred-phone-3573578/
https://www.androidauthority.com/google-pixel-organized-crime-preferred-phone-3573578/
Android Authority
Cops in this country think everyone using a Google Pixel must be a drug dealer (Updated)
Pixel phones are criminals' top pick in Spain's Catalonia for their strong security and mod-friendly design.
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you won't hear stories like this from
OpenAI or Anthropic because they are trying to look invincible, but this is how cutting edge AI development looks behind the scenes
https://x.com/bloc97_/status/1942263691421810820
pic: nous research discovering issues in the middle of a huge training run
OpenAI or Anthropic because they are trying to look invincible, but this is how cutting edge AI development looks behind the scenes
https://x.com/bloc97_/status/1942263691421810820
pic: nous research discovering issues in the middle of a huge training run
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2+ billion of eSIM-equipped systems worldwide can be compromised remotely (more details at the link)
https://security-explorations.com/esim-security.html
https://security-explorations.com/esim-security.html
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Do you have a spare fusion reactor?
They can be modded to transmute mercury into gold as well :)
Regular (fission) nuclear reactors won't work, unless you happen to have a fast neutron-producing "breeder" one.
Please share photos of your project when finished!
https://www.marathonfusion.com/alchemy.pdf
They can be modded to transmute mercury into gold as well :)
Regular (fission) nuclear reactors won't work, unless you happen to have a fast neutron-producing "breeder" one.
Please share photos of your project when finished!
https://www.marathonfusion.com/alchemy.pdf
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TIL there are at least eight people born with DNA combined from three parents already.
https://www.nature.com/articles/d41586-025-02276-5
https://www.nature.com/articles/d41586-025-02276-5
Nature
‘Landmark’ study: three-person IVF leads to eight healthy children
Nature - Long-awaited results suggest that mitochondrial donation can prevent babies from inheriting diseases caused by mutant mitochondria.
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another step to the point where the llm self-improvement takeoff becomes possible
an exercise: list the rest of the required parts
https://arxiv.org/abs/2507.18074
an exercise: list the rest of the required parts
https://arxiv.org/abs/2507.18074
arXiv.org
AlphaGo Moment for Model Architecture Discovery
While AI systems demonstrate exponentially improving capabilities, the pace of AI research itself remains linearly bounded by human cognitive capacity, creating an increasingly severe development...
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the starling memories
TLDW: picture -> spectral synthesizer -> the bird remembers the "song" -> the bird sings -> spectral analyzer -> wow
https://www.youtube.com/watch?v=hCQCP-5g5bo&t=1018s
TLDW: picture -> spectral synthesizer -> the bird remembers the "song" -> the bird sings -> spectral analyzer -> wow
https://www.youtube.com/watch?v=hCQCP-5g5bo&t=1018s
YouTube
I Saved a PNG Image To A Bird
I got a bit concerningly obsessed with birds for a few months.
Follow Sarah and The Mouth! https://linktr.ee/inkydragon
Older bat vid: https://www.youtube.com/watch?v=X4eqkaHkTAI
💗 Support this channel and join an amazing community: http://www.patreon.com/bennjordan…
Follow Sarah and The Mouth! https://linktr.ee/inkydragon
Older bat vid: https://www.youtube.com/watch?v=X4eqkaHkTAI
💗 Support this channel and join an amazing community: http://www.patreon.com/bennjordan…
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anything programmable can be a software defined radio transmitter, if you're persistent enough :)
https://arxiv.org/abs/2506.21069
https://arxiv.org/abs/2506.21069
arXiv.org
TEMPEST-LoRa: Cross-Technology Covert Communication
Electromagnetic (EM) covert channels pose significant threats to computer and communications security in air-gapped networks. Previous works exploit EM radiation from various components (e.g.,...
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augmentations save lives
https://osf.io/preprints/psyarxiv/5c3ba_v1
https://osf.io/preprints/psyarxiv/5c3ba_v1
OSF
Personalized Adaptive Cortical Electro-stimulation (PACE) in Treatment-Resistant Depression
Treatment-resistant depression (TRD) is a leading cause of premature death. For decades investigators have assessed the clinical efficacy of direct brain stimulation for TRD. Outcomes have been inconsistent due to imprecise brain targeting. Minimally invasive…
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medium is not the message, but certainly is an attractor of the messages of a certain kind
https://open.substack.com/pub/reinventscience/p/revive-the-republic-of-letters
https://open.substack.com/pub/reinventscience/p/revive-the-republic-of-letters
www.reinvent.science
Science has a Breaking-in Problem
Let's revive the Republic of Letters
avoid excess complexity and noise at all costs. mvp is not "all features of shitty quality" but "minimum features still decent quality".
or "hypothesis validation code and the commitment to rewrite"
https://minds.md/zakirullin/cognitive
or "hypothesis validation code and the commitment to rewrite"
https://minds.md/zakirullin/cognitive
minds.md
Cognitive load is what matters
There are so many buzzwords and best practices out there, but let's focus on something more fundamental. What matters is the amount of confusion developers feel when going through the code.
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TLDR: to exercise agency you need to understand what's around you and the rules of the game, both explicit and implicit ones
https://arxiv.org/abs/2506.01622
https://arxiv.org/abs/2506.01622
arXiv.org
General agents contain world models
Are world models a necessary ingredient for flexible, goal-directed behaviour, or is model-free learning sufficient? We provide a formal answer to this question, showing that any agent capable of...
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for something completely different:
first 2178 books of the Ritman Library are now digitized & online, safe from the natural disasters
https://embassyofthefreemind.com/en/library/online-catalogue/?mode=gallery&view=horizontal&sort=random%7B1517048201764%7D%20asc&page=1&fq%5B%5D=search_s_digitized_publication:%22Ja%22&reverse=0
first 2178 books of the Ritman Library are now digitized & online, safe from the natural disasters
https://embassyofthefreemind.com/en/library/online-catalogue/?mode=gallery&view=horizontal&sort=random%7B1517048201764%7D%20asc&page=1&fq%5B%5D=search_s_digitized_publication:%22Ja%22&reverse=0
❤3
chat apps will become history
your artificial limbs and senses should feel real
https://www.nature.com/articles/s44287-025-00218-x.epdf
your artificial limbs and senses should feel real
https://www.nature.com/articles/s44287-025-00218-x.epdf
Nature
Cortical somatosensory feedback for brain-controlled bionic hands
Nature Reviews Electrical Engineering - Somatosensory feedback is an essential feature of neural prostheses that aim to restore natural hand dexterity after neurological injuries. This Comment...
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Physical labs are the next frontier and the ultimate data source for the future AIs.
Grounded in real experiments and observations, not interpretations from the web and the books but genuinely /new/ data.
Watch this space.
https://x.com/liamfedus/status/1973055380193431965?s=46
Grounded in real experiments and observations, not interpretations from the web and the books but genuinely /new/ data.
Watch this space.
https://x.com/liamfedus/status/1973055380193431965?s=46
X (formerly Twitter)
William Fedus (@LiamFedus) on X
Today, @ekindogus and I are excited to introduce @periodiclabs.
Our goal is to create an AI scientist.
Science works by conjecturing how the world might be, running experiments, and learning from the results.
Intelligence is necessary, but not sufficient.…
Our goal is to create an AI scientist.
Science works by conjecturing how the world might be, running experiments, and learning from the results.
Intelligence is necessary, but not sufficient.…
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very interesting!
i wonder if the approach used by the TRM/HRM models can be adapted from ARC-AGI back to other reasoning benchmarks usually done on LMs
https://alexiajm.github.io/2025/09/29/tiny_recursive_models.html
i wonder if the approach used by the TRM/HRM models can be adapted from ARC-AGI back to other reasoning benchmarks usually done on LMs
https://alexiajm.github.io/2025/09/29/tiny_recursive_models.html
alexiajm.github.io
Less is More
Recursive Reasoning with Tiny Networks