Science – Telegram
Researchers identify a previously unknown mechanism by which melanoma cancer cells paralyze immune cells through extracellular vesicle secretion, revealing a key strategy of immune evasion and offering new insights into potential immunotherapeutic targets for the deadliest form of skin cancer.
https://www.cell.com/cell/fulltext/S0092-8674(25)01316-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867425013169%3Fshowall%3Dtrue

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A drug once designed for dengue virus, then quietly abandoned by industry, is suddenly back in the spotlight. Study suggests that this antiviral didn’t just slow the dengue virus, it blocked viral replication and significantly reduced infection rates at high doses.
https://www.nejm.org/doi/full/10.1056/NEJMoa2500179

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When users swipe through profiles on dating apps, their brains make split-second decisions based on 2 cognitive processes: one assesses facial beauty and another interprets “vibe” or social context of photo. A beautiful face is an asset, but combined with displays of wealth or status can backfire.
https://www.sciencedirect.com/science/article/abs/pii/S0747563225002390

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Oral bacterium tied to disability severity in multiple sclerosis (MS). Findings connect Fusobacterium nucleatum with MS disease severity. Increasing evidence suggests that the severe gum disease, periodontitis, may contribute to central nervous system disorders through chronic inflammation.
https://www.hiroshima-u.ac.jp/en/news/94860

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Analysis of income, capital gains, and borrowing of Americans finds 40% of the income of "1% wealth holders" is unrealized capital gains not subject to taxation and 1%-2% is borrowing, suggesting that the "Buy, Borrow, Die" is not a dominant tax avoidance strategy among the rich
https://www.sciencedirect.com/science/article/abs/pii/S0047272725002178

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Doubting your doubts may increase commitment to goals: when people who were worried about achieving an identity goal were induced to experience a meta-cognitive doubt, they became more committed to achieving their goal
https://news.osu.edu/how-doubting-your-doubts-may-increase-commitment-to-goals/

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Mass shootings are associated with increased local voter turnout but do not change presidential vote choices, showing that exposure to gun violence mobilizes voters locally without producing broader shifts in national electoral outcomes.
https://www.science.org/doi/10.1126/sciadv.adx5418

https://redd.it/1pzrpxu
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Injectable antibodies in nanoparticles could replace hour-long infusions: A much faster, simpler treatment without an IV bag and an hour of getting needled. Just a single 2-ml shot of a solution containing solid nanoparticles packed with highly concentrated antibodies.
https://newatlas.com/medical-tech/injectable-antibodies-nanoparticles/

https://redd.it/1pzvxje
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Updated Comprehensive Review finds that methylphenidate may reduce ADHD symptoms (inattention, hyperactivity) in children/adolescents, but evidence certainty is low. Non-serious side effects (sleep loss, appetite suppression) are common and long-term effects remain unclear.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD009885.pub4/full

https://redd.it/1q076t0
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Children exposed to high levels of screen time before age two showed changes in brain development that were linked to slower decision-making and increased anxiety by their teenage years
https://www.sgpc.gov.sg/detail?url=/media_releases/astar/press_release/P-20251230-2

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