Weight-loss drugs like Ozempic and Mounjaro can affect libido, causing it to decrease. Doctors attribute this to hormonal changes, side effects like nausea and fatigue, and a general decrease in energy. Although not everyone experiences this, patients are increasingly complaining of a loss of interest in sex.

Some experts note that sudden weight loss and changes in the body can temporarily disrupt hormonal balance. However, these effects usually go away after stopping the drugs.