🔗 Isomorphic Labs — AI-first pharma for real disease cures

56 million people die from illness every year. Isomorphic Labs, a DeepMind spinout backed by Alphabet, is building a drug discovery platform where nearly everything is simulated with AI — and they're now entering human trials.

🔸 AlphaFold 3 models proteins, RNA, DNA, small molecules
🔸 Simulations replace most wet-lab experiments
🔸 Built-from-scratch AI-native pharma company
🔸 Drastically cuts drug development cost and time
🔸 Makes biotech accessible for small teams
🔸 Partnering with big pharma and developing in-house drugs

$600M raised in March. Alphabet backing. Real mission.
This could be the start of the immortality curve Kurzweil talked about.

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🐥 Chickens-as-a-Service: the rise of subnoscription farming

From skyrocketing egg prices to eco-hype and backyard aesthetics — chickens are having a moment.

Rent the Chicken lets anyone try the farming life without commitment. For 4–6 months, you get mobile coops, laying hens, and fresh eggs — then return or adopt.

🔸 Partner network of 45 farmers across the US and Canada
🔸 Ready-to-go coops, no construction needed
🔸 Seasonal rentals with buyout option
🔸 Produces 8–14 eggs per week per package
🔸 $17.6M revenue (last public figure), growing ~20% yearly
🔸 48% sales spike during the pandemic

It’s a demo mode for aspiring homesteaders — and a gentle fix to pet abandonment.

What’s next? Rabbits, goats, micro-pigs?
Would you rent your first herd?

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🗯Build a perfect resume in minutes with Kuse

Kuse is a new AI tool that turns your text, file, or project link into a polished, recruiter-ready portfolio — no design skills needed.

🔸 Upload anything — get a clean, structured resume instantly
🔸 Looks like it was made by a pro designer
🔸 Supports charts, screenshots, and visual case studies
🔸 Export as PDF or live website — ready to send in replies

Try it here

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🪙Send Bitcoin without internet — Jack Dorsey makes it real

Bitchat is a new peer-to-peer chat app that works entirely without internet or mobile signal.

🔸 Uses Bluetooth mesh to relay encrypted messages
🔸 No SIM card, no Wi-Fi, no servers, no login
🔸 Messages are ephemeral and fully private
🔸 Built for protests, outages, or remote areas
🔸 Currently in beta on iOS — Android coming soon

This isn’t a concept.
You can now send Bitcoin without internet.

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🌍 Nigeria wants to be the next India — but AI and visas say otherwise

Nigeria is training 3 million tech workers to become a global outsourcing hub.

But AI is eating entry-level jobs, and Western visa restrictions are blocking access to global markets.

🔸 Over 1.8M applied to the government’s free 3MTT tech program
🔸 Courses cover AI, cybersecurity, software dev — online + 200+ centers
🔸 Startups like AltSchool and Andela link Nigerian talent to global firms
🔸 AI now handles basic coding and customer support tasks once outsourced
🔸 U.S. immigration policies are forcing tech workers to stay home
🔸 Nigeria is building “Talent Cities” and training locals to build its own LLMs

The bet is big — but the game has changed.

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🤖 China just dropped the best open AI model for coding & agents

DeepSeek released Kimi K2, a trillion-parameter model that beats Claude, Gemini, and even GPT-4.1 — and it’s fully open.

Here’s what it can do:

🔸 Matches Claude 4 in reasoning, outperforms DeepSeek v3, Qwen, and GPT-4.1
🔸 Token costs are 5x cheaper than Claude Sonnet or Gemini 2.5 Pro
🔸 Handles 100K-token research with clean visualizations
🔸 Builds full web games — including a Minecraft clone — in one shot
🔸 Plans trips using 17 tools in-browser, from search to booking

And yes — it’s free and open to everyone: kimi.ai

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🧠 Most founders fail to prove product–market fit. This free 9-step template fixes that

Too many pitch decks jump straight to the product. No context, no clarity — just “here’s what we built.”

But if investors don’t understand who it’s for, what’s broken, and why now, they won’t care about your clever solution.

That’s where the PM-Fit Logic framework comes in. Created by startup mentor and researcher Jeroen Coelen, it’s been used by 300+ early-stage teams and VCs to tighten their story and surface real PMF signals.

Here’s how it works:

🔸 You start with the customer — one real segment, not a persona soup
🔸 Define their Job to Be Done — what they’re trying to achieve (not what you want)
🔸 Frame the real problem — the blocker stopping them from reaching that goal
🔸 Map the current alternatives — what they’re using today instead of you
🔸 Point out why those fall short — based on interviews, not assumptions
🔸 Explain the consequence of doing nothing — real stakes, not fluff
🔸 Only then do you pitch your product — framed as the natural solution
🔸 Link your features to the problems and gaps above — with clarity
🔸 Repeat this logic for each segment if needed — buyer ≠ user ≠ approver

You can use the framework in three ways:

🗄A pre-built Google Sheet (color-coded, structured)
🗄A custom GPT tool that scores your PMF logic (0–100)
🗄A whiteboard version for team workshops and accelerators

The end result: a logical, evidence-based story that shows why your product must exist — not just that it does.

No more vague pain points. No more investor confusion. Just clean, customer-first logic that actually holds up.

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💰 China is spending billions to win the AI race

Beijing is using full-scale industrial policy to close the AI gap with the U.S., pouring billions into chips, data centers, and open-source models to make China an AI superpower.

🔸 Government has spent nearly $100B on chip development since 2014
🔸 $8.5B more allocated in April for early-stage AI startups
🔸 Local subsidies cover up to 15% of startup R&D costs
🔸 Entire tech zones like Dream Town in Hangzhou built to incubate AI talent
🔸 DeepSeek, Alibaba, and ByteDance now publish world-class open-source models
🔸 China trains models on curated government datasets aligned with state controls
🔸 Huawei and SMIC racing to produce Nvidia alternatives under U.S. chip bans

While U.S. firms guard closed models, China is betting on open-source to gain influence — and it’s already working.

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🛠 Cool tools for AI agents, coding, and automation

A fresh batch of tools for building smarter workflows, AI agents, content pipelines, and marketing hacks — all tested and useful.

Coding & marketing stack
🔸Firecrawl – scrape the web, make LLM.txt for GEO
🔸Exa – find the unfindable
🔸Hunter – lead enrichment
🔸DataforSEO – search demand & keyword intel
🔸Perplexity MCP – research API
🔸Manus – deep research
🔸Genspark – decks, agents, and pitch prep
🔸VAPI – voice agents (use Livekit if you’re a dev)
🔸Resend – programmatic emails (with new.email)
🔸Docker MCP – agent infra
🔸Supabase – friendly backend and auth
🔸Vercel – hosting

For browsing the web
🔸Browserbase – lets agents browse the web
🔸Playwright MCP – for testing and automation with web data

Automations
🔸Zapier – simple daily workflows
🔸n8n – self-hosted, flexible agent logic
🔸Lindy – best for field mapping automations
🔸Grumloop – browser-based triggers
🔸String.com – PipeDream-style text agent flows
🔸Manychat – IG short-form automation

Content generation
🔸Reel Farm – short-form repurposing
🔸Post Bridge – X-to-everything
🔸GenViral – idea prompts and hooks
🔸Banner Bear – dynamic image content
🔸Arcads – UGC-style AI ad builder

Design
🔸Aurachat – AI-powered design assistant

Building & prototyping
🔸Bolt, Replit, VO, Webflow, Framer – fast landing page tools
🔸Webflow CMS MCP – for programmatic blog creation
🔸Cursor – agentic IDE
🔸Warp – agentic terminal for builders
🔸Claude Code – best coding helper for non-devs

Save this list — it covers 80% of what you need to build fast with AI.

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👆 This simple automation change saves $500+/mo.

Vibe marketing is the new marketing.

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🧪Varda: Making drugs in space

What if the biggest breakthrough in pharma isn't on Earth?

Varda is betting that microgravity can unlock new ways to manufacture complex drugs — and they’re already proving it in orbit.

The startup has raised $329M and completed three missions, becoming the first private lab to operate outside the ISS.

Rethinking pharma through microgravity
🔸 Produces medicines in space to enable unique molecular structures
🔸 Successfully returns drugs to Earth via hypersonic capsules (Mach 25)
🔸 First private lab operating beyond the ISS
🔸 Opened a ground lab in California to prep and analyze payloads
🔸 Already working with major government clients like the Pentagon
🔸 Focused on next-gen monoclonal antibody therapeutics

If they can scale this, the economics will take care of themselves.

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🚕 Taxi drivers are hacking the system — with helper apps

As Uber and Lyft squeeze driver margins, a new class of “driver aid” apps is emerging to fight back quietly, but effectively.

Apps like Mystro, GigU, and Maxymo intercept incoming ride requests and enhance them with real-time info: estimated hourly earnings, mileage, tax impact, and a color-coded profitability score. Green means go — red means decline.

🔸 Drivers can set filters and let the app auto-decline bad rides
🔸 Monthly subnoscriptions cost up to $20, but net earnings rise
🔸 Apps now bypass detection by using Android accessibility services — originally designed for disabled users
🔸 This lets them read screen data and “click” buttons invisibly
🔸 Uber sued GigU in Brazil, but lost on appeal — even regulators backed GigU

Drivers are using tech to fight back — not strikes. It's automation from the bottom up. A shadow market for worker tooling is growing, one ride at a time.

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🔗One site to replace 100 browser tabs

Someone built the Swiss army knife of online tools — and it’s completely free, unlimited, and ad-free.

Here’s what it can do:

🔸 Calculate mortgages, calories, interest, travel time
🔸 Help devs with JSON, RegEx, JWT, and more
🔸 Generate passwords, QR codes, even horoscopes
🔸 Transfer playlists between music platforms
🔸 Convert images, text, time zones, units
🔸 Yes — it can even build your Elden Ring setup

Bookmark it now: 4me.tools

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🎵 ChatGPT promised a feature — so the founder built it

The music app Soundslice never supported ASCII tablature. But ChatGPT kept telling users it did — until the founder gave in and made the hallucination real.

🔸 Soundslice helps musicians practice by syncing notation with video
🔸 It also has an AI sheet scanner that turns photos of standard sheet music into interactive scores
🔸 Users began uploading ASCII guitar tabs — text-based notation like —3—5—7—
🔸 ChatGPT had confidently told people these would work on Soundslice
🔸 Founder Adrian Holovaty discovered the bug after spotting strange uploads in error logs
🔸 He faced a choice: publish disclaimers everywhere — or make it real
🔸 In the end, he built the feature, calling it a “weird case of being forced by misinformation”

It’s likely the first time an AI hallucination turned into an actual product feature. But in a world where LLMs drive user behavior at scale, this might become the new normal.

Sometimes reality bends to fit the prompt.

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🎯 10 phrases that instantly raise red flags for investors

These aren’t always mistakes — but they can signal the wrong things if not framed carefully.

🔸 “We’re targeting a $20–100M exit.”
Sounds like you’re building a quick flip, not a long-term company.

🔸 “We’re a bit burned out.”
Honest, but makes me question whether the team can go the distance.

🔸 “We need money to start sales and marketing.”
Do you already know what works? Having proof of early traction builds trust.

🔸 “Our CTO is leaving.”
That happens. Just have a plan and communicate it clearly.

🔸 “Our burn rate is high, so we need more capital.”
Show that you’re in control. It’s not about the spend — it’s about the strategy behind it.

🔸 “We haven’t really looked into competitors.”
If the market exists, you need a clear position within it.

🔸 “Sales are flat, but we’re confident they’ll grow.”
Optimism is great — but show a go-to-market strategy, not just hope.

🔸 “The market is still small.”
Fine — if you can clearly explain how it gets big.

🔸 “We’re cheaper than competitors.”
That’s not a moat. Focus on value, not discounts.

🔸 “They’re not paying customers, just trials.”
Free users aren’t revenue. Be precise. Real traction beats inflated metrics.

Small things kill trust. Investors don’t just back the idea — they back the team.

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🧠 Real-time AI avatars just got a serious upgrade

While Musk experiments with Grok-powered characters like Ayna and Rudy, Hedra has quietly launched a real-time avatar engine — and it might change the game.

🔸 Costs just $0.05/min — 15x cheaper than HeyGen or Character.ai
🔸 Built on LiveKit infra with sub-100ms latency
🔸 Compatible with any LLM or TTS model — not tied to one stack
🔸 Lets you create avatars from a single image in any style: photorealistic, animated, or stylized

Live demo now available 👈

If this holds up, we’re looking at the future of interactive AI interfaces — cheap, low-latency, and model-agnostic.

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🧪 Latent Labs brings push-button protein design to the browser

Latent Labs has launched Latent-X — a web-based AI model that lets anyone generate novel protein structures with a click.

Built by ex-DeepMind researchers, it aims to democratize protein engineering with atomic-level precision.

🔸 No-code platform generates protein binders and macrocycles from a simple target
🔸 Lab tests show 91–100% hit rates for macrocycles and 10–64% for mini-binders
🔸 Delivers picomolar to micromolar binding affinities, not just predictions like AlphaFold
🔸 Free access for academia and startups; licensing for commercial use

With traditional wet-lab work costing millions and taking months, Latent-X offers a software-like approach to biotech — fast, cheap, and accessible from any browser.

This could mark the start of programmable biology for real.

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🧠 Turn ChatGPT into anyone — from therapist to web developer

A new site just dropped with hundreds of prompts that instantly turn ChatGPT into any expert you want.

🔸 Become a tutor, lawyer, coder, coach — pick a role
🔸 One click and you’ve got an AI investor or language teacher
🔸 Just copy the prompt and paste it into ChatGPT
🔸 Works with the free version too

Try it here 👉 Agentic Workers 👈

Tried any good ones? Drop your favorites.

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