Clinical trials typically evaluate psychedelics through short-term before-and-after measures to assess treatment efficacy, but longer-term and lifelong

While clinical trials investigate psychedelics for addiction treatment, new population-level research indicates that LSD is associated with reduced alcohol use disorder in naturalistic settings.

In this episode Hamilton sits down with Dr. Casey Paleos to discuss his psychiatric and medical training, his path to involvement in the MAPS MDMA clinical trial, and his impressions of the 2024 FDA rejection of MDMA for therapeutic use in the treatment of…

Domnauer discusses a mushroom that reliably produces fairy-tale-like visions.

In today's dispatch, we're unpacking what we actually know about the pineal gland.

Same blotter. Very different chemistry. NBOMes aren’t acid — and the margin for error is razor-thin.