Day of Immunology, 29 April
DOI 2019

"Cancer Checkpoint Blockade"

https://www.dayofimmunology.org

🆔@niima_usern
🆔@usern_net

Happy Professor Day🌹

@niima_usern

The Immune System for Public: Interview with the National TV3

سیستم ایمنی بدن و بیماریهای آن به زبان ساده برای عموم مردم در مصاحبه با شبکه سه سیما

@niima_usern
@cip_usern
@usern_net

🎉بیش از پانصد مقاله با افیلیشن یوسرن در اسکوپوس به ثبت رسید.

@usern_net

Physiology and Pathology of Immunology

Edited by Nima Rezaei

The "Physiology and Pathology of Immunology" book covers a spectrum of high-impact knowledge on the complex interplay between the environment, genes, and immunity that culminates in a generation of notorious processes of immune-related disorders. From evolution of regulatory T-cell function, gigantic cytokine networks within the human body to host-pathogen interactions of Chagas disease and Parkinson's disease, the Physiology and Pathology of Immunology goes further to decipher new codes from the immunity enigma, making it essential for experienced and new learners who wish to join the galaxy of modern immunology.

To free download the chapters:
https://www.intechopen.com/books/physiology-and-pathology-of-immunology

#book

@niima_usern
@cip_usern
@usern_net

عده ای از محققین ایرانی با راه اندازی وبسایتی به بررسی مطالعات مهم و چالش برانگیز پزشکی می‌پردازند و آنها را از نظر سوگیری های مهم ارزیابی می کنند که نتایج آن در وبسایت قابل مشاهده است.
ظاهرا بعد از افزایش تعداد همکاران در این وبسایت، تعداد مقالات مورد بررسی نیز افزایش می باید. بر اساس اطلاعات ذکر شده، این پایگاه، اولین وبسایتی است که روش شناسی مطالعات را می سنجد

unravelmedicine.com

🌐EAACI Junior Membership for FREE!

European Academy of Allergy and Clinical Immunology

🔹EAACI Junior Membership shall be available to all those who are aged 35 years or less at the time of renewal of their subnoscription.
🔹The benefits of Junior Membership shall be determined by the Executive Committee and publicised at Congresses, Joint Symposia, and other EAACI events, as well as on forms for enrolment and membership renewal.

https://www.eaaci.org/40-organisation/bylaws/2378-junior-membership

https://registration.eaaci.org/EAACIMemberRegistration.aspx

#Membership

@niima_usern
@cip_usern

🏵4th USERN Congress
Budapest, Hungary
November 2019

🌐Call for Abstracts and Early Registration.
Deadline: July 1st, 2019
https://bit.ly/2HfC6xo

🔖Travel grants and scholarships are available for top accepted abstracts

⁉️For more information:
http://userncongress.com

@usern_net
@USERNCongress

State of the Art in Immunotherapy of Neuroblastoma

New paper by NIIMA USERN interest group

Neuroblastoma (NB) is a common and deadly malignancy mostly observed in children. Evolution of therapeutic options for NB led to the addition of immunotherapeutic modalities to the previously recruited chemotherapeutic options. Molecular studies of the NB cells resulted in the discovery of many tumor-associated genes and antigens such as MYCN gene and GD2. MYCN gene and GD2 surface antigen are two of the most practical discoveries regarding immunotherapy of neuroblastoma...

To read the full paper:
https://www.futuremedicine.com/doi/full/10.2217/imt-2019-0018

#Paper

@niima_usern
@cip_usern
@usern_net

Integrative analyses of triple negative dysregulated trannoscripts compared with non‐triple negative tumors and their functional and molecular interactions

New paper by NIIMA USERN interest group

Triple‐negative (TN) tumors are a subtype of breast cancer with aggressive behaviors and limited targeted therapies. We aimed to conduct integrative strategy to analyze gene and miRNA available microarray data as well as bioinformatic analyses to catch a more inclusive picture of pivotal dysregulated trannoscripts and their interactions in TN tumors. 
This study suggests that dysregulated TFs and miRNAs have pivotal roles in regulation of TN oncotrannoscriptomic profile and might become both biomarkers and therapeutic targets...

To read the full paper:
https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.28804

#Paper

@niima_usern
@cip_usern
@usern_net

Novel Methods to Improve the Efficiency of Radioimmunotherapy for Non-Hodgkin Lymphoma

New paper by NIIMA and CIP USERN interest groups

Radioimmunotherapy (RIT) is a novel strategy for treating non-Hodgkin lymphoma (NHL).
Several studies have shown the promising results of using RIT in NHL, which have led to FDA approval for two RIT agents in treating low grade NHL.
In this paper, novel methods that improve the efficiency of RIT and reduce its toxicity through various mechanisms are reviewed...

To read the full paper:
https://www.tandfonline.com/doi/abs/10.1080/08830185.2019.1588266?journalCode=iiri20

#Paper

@niima_usern
@cip_usern
@usern_net

Cancer Immunotherapy: The way to the Nobel Prize in Medicine

To read the full paper:
http://acta.tums.ac.ir/index.php/acta/article/view/7535

#Paper

@niima_usern
@cip_usern
@usern_net

Roles of Myeloid-Derived Suppressor Cells in Cancer Metastasis: Immunosuppression and Beyond

New paper by NIIMA, CIP, and BrCA USERN interest groups

Metastasis is the direst face of cancer, and it is not a feature solely dependent on cancer cells; however, a complex interaction between cancer cells and host causes this process.
Myeloid-derived suppressor cells (MDSCs) are key components of tumor microenvironment that favor cancer progression...

To read the full paper:
https://link.springer.com/article/10.1007%2Fs00005-018-0531-9

#Paper

@niima_usern
@cip_usern
@usern_net

🌐 CIMT Membership for FREE!

Association for Cancer Immunotherapy

🔹CIMT accepts applications of individuals active in the discovery and translation of cancer immunology and immunotherapy.

🔹Membership in the association is free and gives you the opportunity to:

🌀connect with a network of scientists, physicians, organizations, and institutes that actively work in the field of cancer immunotherapies
🌀participate in our working groups
🌀be eligible to serve on CIMT committees and in leadership roles

https://www.cimt.eu/membership

#Membership

@niima_usern
@cip_usern
@usern_net

PhD position in Homburg, Germany
Saarland University - Physiology Institute

PhD position (E13/2) in cellular & molecular immunology

🔹A young and motivated departrnent which focusses on deciphering immune cell function, particularly interested in investigating the effector function of Cytotoxic T lymphocytes which are an important part of the adaptive immune system and in the long term in immunotherapy for Cancer.

🔹You are a highly motivated student with a masters degree in biolory or related field, chemistry or pharmacy and someone who enjoys working in an intemational interdisciplinary team.
The position is available immediately and will be funded by the DFG.

🔹If you are interested in such a PhD position, contact:
Dr. Varsha Pattu 
Saarland University
Centre for Integrative Physiolory und Molecular Medicine Department
Cellular Neurophysiolory
e-mail: varsha.pattu@uks.eu

#PhD_position

@cip_usern
@niima_usern

Cancer Research Institute Postdoctoral Fellowships

✅The Cancer Research Institute (CRI) provides funding to ensure that the most promising postdoctoral scientists receive the critical financial support and continued career training needed to pursue their lifesaving work.

✅CRI invites postdoctoral fellows working in both fundamental immunology and tumor immunology to apply for funding.

✅Fellows receive up to $175,500 over three years to cover the cost of salary, insurance, and other research-related expenses, such as travel to conferences and meetings.

✅For more information:
http://www.cancerresearch.org/scientists/fellowships-grants/post-doctoral-fellows/application-guidelines

#Postdoc

@niima_usern
@cip_usern
@usern_net

Clinic and Laboratory Integration Program

✅The Cancer Research Institute funds research aimed at furthering the development of immunological approaches to the diagnosis, treatment, and prevention of cancer. The Institute's mission is to bring effective immune system-based therapies to cancer patients sooner.

✅The Clinic and Laboratory Integration Program (CLIP) grants provide catalytic support for translational laboratory studies designed to answer new specific scientific questions that arise in the clinic, with special focus on improving immunotherapy for cancer patients.

✅CLIP grants provide up to $200,000 over a two-year period.

✅For more information:
http://www.cancerresearch.org/scientists/fellowships-grants/translational-research-grants/clip-application-guidelines

#Grant

@niima_usern
@cip_usern

iATLAS
CRI Awards Grant to Develop Powerful Genomic Data Resource for Cancer Immunotherapy Researchers

✅The CRI iAtlas database is the first comprehensive effort in immuno-oncology to address the recent National Cancer Moonshot Blue Ribbon Panel recommendation to establish a pan-cancer immune atlas that would help catalyze new research in cancer immunotherapy.

✅The CRI iAtlas will serve as a central knowledge base to capture data on the tumor microenvironment and its impact on anti-cancer immune responses. Data generated by the working group, which includes molecular profiling of over 10,000 tumors across 33 tumor types as well as a series of results on immune-tumor interaction and response mechanisms, will provide rich characterizations of the relationship between tumors and the immune microenvironment and its impact on patient outcomes:
https://www.cri-iatlas.org

✅For more information:
http://cancerresearch.org/news/2017/cri-awards-grant-to-develop-powerful-genomic-data

#Grant

@niima_usern
@cip_usern

Comparison of the effects of adipose tissue mesenchymal stromal cell-derived exosomes with conditioned media on neutrophil function and apoptosis

New paper by USERN interest groups

🌀Mesenchymal stromal cells (MSCs)-derived exosomes and conditioned media (CM) increased neutrophil phagocytosis capacity.

🌀The MSC-CM augmented neutrophil reactive oxygen species (ROS) production, but it couldn’t decrease neutrophil apoptosis.

🌀MSC-xosomes could decrease neutrophil apoptosis.

🌀MSC-exosomes and CM may be useful for increasing immunity by improving neutrophil function and survival.

To read the full paper:
https://www.sciencedirect.com/science/article/pii/S1567576919306964?via%3Dihub

#Paper

@niima_usern
@cip_usern
@usern_net

IL-17 and colorectal cancer: From carcinogenesis to treatment

New paper by USERN interest groups

🌀Interleukin-17 can promote colorectal cancer tumorigenesis by several pathways.

🌀Interleukin-17 is associated with metastasis and poor prognosis in colorectal cancer.

🌀Interleukin-17 is a protective cytokineagainst colorectal cancer.

🌀Interleukin-17 can be used as a diagnostic marker in colorectal cancer.

🌀Interleukin-17 has been a new target in treatment of colorectal cancer patients.

To read the full paper:
https://www.sciencedirect.com/science/article/abs/pii/S1043466619300092?via%3Dihub

#Paper

@niima_usern
@cip_usern
@usern_net

USERN RESEARCH WEEK

🔹USERN SUMMER EVENT
🔹August 2019
🔹For more information and register:
https://docs.google.com/forms/d/e/1FAIpQLSfRTbSIU15Lb9tkyPSacghOW_85EiWj0UHiU-sYeyfxHdzy7w/viewform

#Workshop

@niima_usern
@usern_net