The Crispr Baby Scientist Is Back. Here’s What He’s Doing Next | WIRED

So what do you think about him? Is it ok to fund his new startup to cure Muscular Distrtophy?

https://www.wired.com/story/the-crispr-baby-scientist-is-back-heres-what-hes-doing-next/

Neuroscientists have created a mood decoder that can measure depression | MIT Technology Review

Finally!!! You have no idea how angry I am because of current issues with clear identification of depression without those ancient tests. I'm happy that there is at least some progress in it


https://www.technologyreview.com/2022/12/14/1064906/mood-decoder-measure-depression/

Fun fact, I have a dysgraphia ( lol, you know it already). And ChatGPT understand me very well. What's more important, it can translate my gibberish into something that people can understand well. Im just telling him, make this sound awesome.

But since I have ADHD, I'm too lazy to do it 😁

Scientists identify a brain pathway for overcoming fear - Big Think

TLDR

It's 5-HT2C. And guess what?

Psylocybin,LSD and MDMA affect 5-HT2C

https://bigthink.com/neuropsych/fear-brain-pathway/

3 Years ago I spent 28 hours on the bus and then 16 on a boat through the Amazon ( there was an airplane option actually, but I never chose easy way 😁 ) to talk to shamans and ask them what do they think about all the tech innovation happening now from genetic modifications to AI and ofcause their experience with Auhuasca. It was fun to watch it again, thanks to Google memories. Just wanted share his face when I've asked him about his first time 😍

Experts debate the risks of made-to-order DNA – Ars Technica
https://arstechnica.com/science/2022/12/experts-debate-the-risks-of-made-to-order-dna/amp/

SBF was prescribed for Adderall (Stimulant) and Emsam Patch (MAOI) And am not a super expert, but this is a fucking bad combo its at least dangerous and sometimes deadly according to Psychonautwiki and a few other sources, I don't know how long he used it he literally destroyed his dopamine system and now everything is more clear to me ;) https://slate.com/technology/2022/12/sam-bankman-fried-ftx-emsam-patch-testimony-arrested.html

Human Brain Organoids Implanted Into Mouse Cortex Respond to Visual Stimuli for First Time - Neuroscience News

So, it seem that we have a great tool now to perform tests 😁

" This experimental setup opens up unprecedented opportunities for investigations of human neural network-level dysfunctions underlying developmental brain diseases,” said Kuzum. "

https://neurosciencenews.com/organoid-transplant-visual-stimuli-22149/

The death of SynthBio companies and my other predictions for Biotech in 2023

Josiah knows this shit like no one else.

https://amateurgods.substack.com/p/the-death-of-synthbio-companies-and

ChatGPT and AI language tools banned by AI conference for writing papers - The Verge

"The conferences who will enforce such rules will be the biggest losers for 2023."

https://www.theverge.com/2023/1/5/23540291/chatgpt-ai-writing-tool-banned-writing-academic-icml-paper

Psychodelics in on of the top 5 topics for 2023 by Economist.

MDMA, Psylocybin and Ketamine Will most likely be approved for medical use in US and UK

https://www.youtube.com/watch?v=nv3iOH_XYdo

Kids' Incredible Learning May All Be Down to 1 Chemical in The Brain : ScienceAlert

TLDR:GABA

https://www.sciencealert.com/kids-incredible-learning-may-all-be-down-to-1-chemical-in-the-brain

Company Using ChatGPT for Mental Health Support Raises Ethical Issues


If there is a chance that someone fill finally define what is Ethical ?

https://www.businessinsider.com/company-using-chatgpt-mental-health-support-ethical-issues-2023-1

Scientists create new category of non-alcoholic ‘spirit’ - The Spirits Business

Because during alcohol in 2023 is like riding a horse to get to the office ( first of all I'm joking at myself 😂)

Let's drink GABA and be fast learners as kids ( I mean an article 2 publications ago )

https://www.thespiritsbusiness.com/2023/01/scientists-create-new-category-of-non-alcoholic-spirit/

Usually we see examples of either optical illusions. (you name it) or textual ( Like if you can still read words when symbols in deffirnet order ). This image is a nice example of one type of input affect how we process the other one. (At least for some people). More in the comments.

TLDR:

Pince Harry took Ayahuasca

He said: “After taking ayahuasca with the proper people... I suddenly realised – wow! – it’s not about the crying. She [Diana] wants me to be happy. So this weight off my chest was not the need to cry, it was the acceptance and realisation that she has gone, but that she wants me to be happy and that she’s very much present in my life".

( Quote from the other sources)

https://www.nytimes.com/2023/01/10/well/psychedelics-grief-mental-health.html

(relatively) New book and seems to be super exciting.


Reality Switch Technologies: Psychedelics as Tools for the Discovery and Exploration of New Worlds


" In 2015, he collaborated with DMT pioneer Dr. Rick Strassman to develop a model for the repurposing of the target-controlled intravenous infusion technology used in anaesthesiology to allow the DMT state to be safely and stably extended for an indefinite period of time. It is hoped that this technology will be used to allow extended sojourns in the DMT space for detailed exploration and mapping of the space, as well as for performing experiments and establishing communication with contacted intelligences."

Holyfuckigshit tht's exactly what I'm planning.

https://www.amazon.com/dp/1739110102

Humans are overvalued 😆😆😆

Meet the podcast with ChatGPT.

It's not just a podcast it's a podcast led by Reid Hoffman (PayPal/LinkedIn/Greylock)

https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5zb3VuZGNsb3VkLmNvbS91c2Vycy9zb3VuZGNsb3VkOnVzZXJzOjIwNTMyMzI1NC9zb3VuZHMucnNz/episode/dGFnOnNvdW5kY2xvdWQsMjAxMDp0cmFja3MvMTQyMTc4NTkyNA?ep=14

The changes in the way we work will be massive. The only way people will be able to outperform AI is through imagination. The use of Psychedelics will probably be the only option to compete. There is no way we will be able to do it without it. It's not the question of IF anymore. It's When. I just realized that Proposal 122 ( decriminalization of multiple Psychedelics including DMT ) and the release of ChatGPT both happened almost at the same time in late November 2022. Remember this date. This is fucking huge.

DMTx

it's going to be massive

"The DMTx extended peak would be five times stronger than Ayahuasca and can theoretically last many hours.  The acceleration of the entry, the intensity of the peak, and the duration of the DMT experience can literally be programed, or “dialed-in,” even adjusted during the experience, for different therapeutic, advanced problem solving, and consciousness explorations experiences. It can be quickly “turned off” if any safety concerns become apparent, therefore it is unlike any psychedelic experience previously possible."

https://www.dmtx.org/

3D Organoid Models Show Brain Mechanisms of Tourette Syndrome - Neuroscience News

I want to play with brain organoids, just curious how complex is is for a home-lab in a "backyard/kitchen" 😆

https://neurosciencenews.com/tourette-brain-organoid-22281/