2019 first breakthrough endogenous DMT research. Usually it takes about 5 years from first studies to pivotal moment, public attention and exponential growth of interest ( Transformers paper in 2017 -> ChatGPT in 2022 etc...)

I predict in 2024 we will have a huge breakthrough event such as publicly accepted and popularized study/event which will lead to huge spike in finding and commercialization.



https://youtu.be/My95s6ZryPg

Ok, let's dive into more practical things. You've made it, now what ?

Integration = connection ( of your Psychedelics experience to your day to day life)

Research paper in the comments

80 years 🤓

Let's celebrate it this pivotal moment.


"Bicycle Day", the first recorded LSD "trip" by Albert Hofmann, April 19, 1943. This is celebrated on April 19 annually, generally through the use of LSD.

UK university launches postgraduate course in clinical use of psychedelics | Drugs | The Guardian

Wanna be a student again

https://www.theguardian.com/society/2023/apr/21/uk-university-launches-postgraduate-course-in-clinical-use-of-psychedelics-exeter

New and quite motivainal intro and Great review of the latest research activities in psylocibin in the end.

For those who are microdosing, I also ecourage you to join this biggest study and contribute in the most exciting research.



https://youtu.be/qry8K7KPHIQ

A researcher called Tim Landgraf even created a robot honey bee that entered a hive and was able to communicate with the other bees.

It was said to be able to tell the other bees to stop and even where to fly.

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Although Bakker presents the research as a good thing, she does note that it raises "a lot of philosophical and ethical questions."

Scientists won't be stopping with bats and bees and lots of other animals could be communicated with.

There are even said to be plans for scientists to try and talk to plants.https://www-thesun-co-uk.cdn.ampproject.org/c/s/www.thesun.co.uk/tech/21306708/ai-scientists-talk-to-animals-artificial-intelligence/amp/

Organoid Intelligence: Computing on the Brain - IEEE Spectrum

“We’ve recapitulated the key features of the pathology. We can see the loss of dopaminergic neurons, we see the appearance of protein aggregates that are relevant to the disease,” said Schwamborn, whose lab has developed an organoid model of Parkinson’s. These platforms allow them to study, on a small scale, Parkinson’s development in a cellular network context that monolayer cultures cannot: “That’s the major advantage. We can see features of the disease that we know are happening in patients but so far have been unable to recapitulate in the lab. Now, finally, we can do that.”

https://spectrum.ieee.org/organoid-intelligence-computing-on-brain

Sam Altman, chief executive of OpenAI, is chairman of a start-up that aims to tap into the promise that psychedelic drugs have shown in clinical trials — and make them broadly available for people who suffer from mental health and drug-use disorders. The firm, Journey Colab, is partnering with a luxury rehab clinic, All Points North, to shepherd drugs like MDMA and psilocybin through late-stage trials and design a model for administering them to patients.

https://www.washingtonpost.com/business/2023/04/22/sam-altman-psychedelics-mental-health/

Dropbox is laying off 500 people and pivoting to AI - The Verge

Hahaha, stage 1 is launched. 🔥

“In an ideal world, we’d simply shift people from one team to another. And we’ve done that wherever possible,” Houston writes. “However, our next stage of growth requires a different mix of skill sets, particularly in AI and early-stage product development. We’ve been bringing in great talent in these areas over the last couple years and we’ll need even more.”


1. In order to survive you need to learn AI
2. After you learned AI you use AI
3. More you use AI more it lerns to be better than you.



https://www.theverge.com/2023/4/27/23700629/dropbox-laying-off-500-people-pivoting-ai

New biocomputing method uses enzymes as catalysts for DNA-based molecular computing
https://phys.org/news/2023-05-biocomputing-method-enzymes-catalysts-dna-based.html

American Medical Association to Issue First New Code for Psychedelic Therapies - MAPS Public Benefit Corporation


This is a major step forward to enabling broad and equitable access to psychedelic therapies,” said Kabir Nath, CEO, COMPASS Pathways. “This collaboration with MAPS PBC to develop a new CPT code aims to ensure that psychedelic therapies, if approved, could be integrated into healthcare systems, reimbursed by payers, and made available to the people who need them.”


https://mapsbcorp.com/press-releases/american-medical-association-to-issue-first-new-code-for-psychedelic-therapies/

Psychedelic medicine is coming—but who’s going to guide your trip?
https://www.nationalgeographic.com/premium/article/psychedelic-medicine-trip-mdma-psilocybin-therapy

Roche bets on organoids to shake up drug discovery, development

“I'm convinced that one can implement human organoids at every step of the way—from target identification and target validation through preclinical safety and efficacy to stratification in clinical trials,” 
Hans Clevers, M.D., Ph.D., a pioneer in organoids research.

https://www.fiercebiotech.com/biotech/roche-creates-organoid-research-institute-shakeup-drug-discovery-and-development

DMT Users Are Using AI to Draw the Strange Beings They Meet While Tripping

Looks like a great plan 👌

I'm inn

https://www.vice.com/en/article/qjv89d/dmt-users-are-using-ai-to-draw-the-strange-beings-they-meet-while-tripping

Very detailed DMT intensity scale and Effect index. 🔥

https://effectindex.com/articles/dmt

A Lucid Death: Sparks of Consciousness Detected in Dying Brains - Neuroscience News
https://neurosciencenews.com/death-nde-consciousness-23161/

Scientists unveil plan to create biocomputers powered by human brain cells + interview with Prof Thomas Hartung (senior author of the paper) - Robohub
https://robohub.org/scientists-unveil-plan-to-create-biocomputers-powered-by-human-brain-cells-interview-with-prof-thomas-hartung-senior-author-of-the-paper/

BEEF series: WTF they ate to have such Psychedelics effect⁉️

SPOILER WARNING

I bet you probably saw this and you maybe have a question, what exactly they ate for those halucenogetic effects.

While I can't say for sure and there is no information on the internet Im almost certain it was a Belladonna

Why?

Well first of all there are not so many psychoactive berries but it's not the main thing.

The second, we see that it's very poisoneus since they were vomiting a lot. Belladonna is also extremely toxic.

But the main thing is that the effect demonstrated in the movie doesn't look like a classical Psychedelics effect from typical serotonin-receptor activation drugs (Psylocibin,LSD, DMT, Mescaline etc..) which perturbs perception system in our brain.

The effect is different and is reminding the effects from trophana alcaloids (Atropine, Scopolamine, etc) which are a main psychoactive components of Belladonna. Those trophanes affect our error detection and synchronization system in the brain which synchronize our internal prediction module with external perception module. That's why she saw a different types of Psychodelics effect in the movie compared to classical hallucinations. like when movie character saw a tree branch instead of a gun. Internal prediction system decided that it's more likely in current environment to see a tree branch and since the error correction system was turned off by trophanes the information form perception that it's actually a gun haven't appeared and as a result a movie character experienced such trip.


"The tropane alkaloids are notable in that they often elicit what are called true hallucinations — these aren’t visions that are recognisable as such, but hallucinations that blend perfectly with the environment. With the classic psychedelics, the user is, more often than not, aware that their eyes-open visuals are distinct from the normal waking world. However, this is not always the case with the tropanes. When consumed orally, the effects are often delayed and can sneak up on the user, who might assume the plant to be inactive, only to realise some time later that they spent the preceding two hours entertaining guests at a party that never happened. In this way, tropane intoxication is often likened more to a waking dream than a psychedelic trip" - from Reality Switch Technologies book.

Now you can share it with friends and pretend to be smart person. 🤪

If you want to see more posts like this, don't be shy drop some emoji 🙊.


https://youtu.be/AFPIMHBzGDs

BeautyMatter | Customized Nootropics Start-Up Thesis Raises $8.4 Million Series A
https://beautymatter.com/articles/nootropics-startup-thesis-raises-8-4-series-a