New biocomputing method uses enzymes as catalysts for DNA-based molecular computing
https://phys.org/news/2023-05-biocomputing-method-enzymes-catalysts-dna-based.html

American Medical Association to Issue First New Code for Psychedelic Therapies - MAPS Public Benefit Corporation


This is a major step forward to enabling broad and equitable access to psychedelic therapies,” said Kabir Nath, CEO, COMPASS Pathways. “This collaboration with MAPS PBC to develop a new CPT code aims to ensure that psychedelic therapies, if approved, could be integrated into healthcare systems, reimbursed by payers, and made available to the people who need them.”


https://mapsbcorp.com/press-releases/american-medical-association-to-issue-first-new-code-for-psychedelic-therapies/

Psychedelic medicine is coming—but who’s going to guide your trip?
https://www.nationalgeographic.com/premium/article/psychedelic-medicine-trip-mdma-psilocybin-therapy

Roche bets on organoids to shake up drug discovery, development

“I'm convinced that one can implement human organoids at every step of the way—from target identification and target validation through preclinical safety and efficacy to stratification in clinical trials,” 
Hans Clevers, M.D., Ph.D., a pioneer in organoids research.

https://www.fiercebiotech.com/biotech/roche-creates-organoid-research-institute-shakeup-drug-discovery-and-development

DMT Users Are Using AI to Draw the Strange Beings They Meet While Tripping

Looks like a great plan 👌

I'm inn

https://www.vice.com/en/article/qjv89d/dmt-users-are-using-ai-to-draw-the-strange-beings-they-meet-while-tripping

Very detailed DMT intensity scale and Effect index. 🔥

https://effectindex.com/articles/dmt

A Lucid Death: Sparks of Consciousness Detected in Dying Brains - Neuroscience News
https://neurosciencenews.com/death-nde-consciousness-23161/

Scientists unveil plan to create biocomputers powered by human brain cells + interview with Prof Thomas Hartung (senior author of the paper) - Robohub
https://robohub.org/scientists-unveil-plan-to-create-biocomputers-powered-by-human-brain-cells-interview-with-prof-thomas-hartung-senior-author-of-the-paper/

BEEF series: WTF they ate to have such Psychedelics effect⁉️

SPOILER WARNING

I bet you probably saw this and you maybe have a question, what exactly they ate for those halucenogetic effects.

While I can't say for sure and there is no information on the internet Im almost certain it was a Belladonna

Why?

Well first of all there are not so many psychoactive berries but it's not the main thing.

The second, we see that it's very poisoneus since they were vomiting a lot. Belladonna is also extremely toxic.

But the main thing is that the effect demonstrated in the movie doesn't look like a classical Psychedelics effect from typical serotonin-receptor activation drugs (Psylocibin,LSD, DMT, Mescaline etc..) which perturbs perception system in our brain.

The effect is different and is reminding the effects from trophana alcaloids (Atropine, Scopolamine, etc) which are a main psychoactive components of Belladonna. Those trophanes affect our error detection and synchronization system in the brain which synchronize our internal prediction module with external perception module. That's why she saw a different types of Psychodelics effect in the movie compared to classical hallucinations. like when movie character saw a tree branch instead of a gun. Internal prediction system decided that it's more likely in current environment to see a tree branch and since the error correction system was turned off by trophanes the information form perception that it's actually a gun haven't appeared and as a result a movie character experienced such trip.


"The tropane alkaloids are notable in that they often elicit what are called true hallucinations — these aren’t visions that are recognisable as such, but hallucinations that blend perfectly with the environment. With the classic psychedelics, the user is, more often than not, aware that their eyes-open visuals are distinct from the normal waking world. However, this is not always the case with the tropanes. When consumed orally, the effects are often delayed and can sneak up on the user, who might assume the plant to be inactive, only to realise some time later that they spent the preceding two hours entertaining guests at a party that never happened. In this way, tropane intoxication is often likened more to a waking dream than a psychedelic trip" - from Reality Switch Technologies book.

Now you can share it with friends and pretend to be smart person. 🤪

If you want to see more posts like this, don't be shy drop some emoji 🙊.


https://youtu.be/AFPIMHBzGDs

BeautyMatter | Customized Nootropics Start-Up Thesis Raises $8.4 Million Series A
https://beautymatter.com/articles/nootropics-startup-thesis-raises-8-4-series-a

Study presents large brain-like neural networks for AI
https://techxplore.com/news/2023-05-large-brain-like-neural-networks-ai.html

Psychonauts by Mike Jay review – the drug-takers who changed history | Science and nature books | The Guardian


Ok, I don't want to be on Forbes list anymore, now I want to be in the next release of this book. 🤪


https://www.theguardian.com/books/2023/may/10/psychonauts-by-mike-jay-review-the-drug-takers-who-changed-history

https://youtu.be/eIxVfln02Ss

Skill level #novice

Not all drugs are "good"

But this shit is especially evil

I haven't thought in my entire life that I will hear that there is something that is 100 times more potent and dangerous that heroine and now it's flooded streets worldwide.

https://youtu.be/LxyyvW_fcqw

Next-level CRISPR gene editing: No viruses required

“Basically, what we’ve done is taken this template DNA and damaged it,” said Chris Richardson, corresponding author of the study. “We’ve in fact damaged it in the most severe way I can think of. And the cell doesn’t say, ‘Hey, this is junk; let me throw it away.’ What the cell actually says is, ‘Hey, this looks great; let me stick it into my genome.’”

https://newatlas.com/biology/nonviral-method-increases-gene-editing-efficiency-threefold/

https://youtu.be/ba5pAjM8HZM

Skill level #intermediate

Mushrooms Appear to Have Electrical 'Conversations' After It Rains
https://www.sciencealert.com/mushrooms-appear-to-have-electrical-conversations-after-it-rains

Asimov Unknowingly Pioneered Modern Prompt Engineering | HackerNoon
https://hackernoon.com/asimov-unknowingly-pioneered-modern-prompt-engineering

Psychedelics for Mental Health | Psychedelics Today

Great easy-to-use FAQ for most common Psychedelics with links to corresponding research papers.

Skill level #novice

https://psychedelicstoday.com/psychedelics-for-mental-health/