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Psychedelic Consciousness ( ex Unstoppable Technologies)
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Brain therapy: Between Science and Businesses

Psychedelic Consciousness research: DMT, LSD, MDMA, 5MEO-DMT, Ketamine, Psilocilybin, Ibogaine...

#Psychedelics #Consciousness #Neuroscience
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Responsible Psilocybin use 101

Recently I wrote a short guideline on how to try shrooms / truffles for the first time when someone asked me. Since I'm getting a number of questions on this topic probably it makes sense to share it here. So let's go.

Well, I should say that it can be ilegal in your country so let's suppose it's a guideline for a trip inside a trip to Amsterdam. Also I should note that it can be dangerous even with all that I will mention in the guideline and it's not recommend for some people at all so first of all check all your conditions.

(Some conditions: Personal or family psychotic disorders including schizophrenia, bipolar disorder. Personality disorders such as borderline, heart conditions, not stable mental state and who use certain types of medications. Better check it in other sources)

It's important to note that it's not an extensive guideline bit rather short checklist to keep in mind to maximize the probability of successful trip and minimize the potential negative effect. But keep in mind that mushrooms are very unpredictable, so trust ,let go and be open 😁


1. Why? (Purpose /Set)

It's essential to carve out a clear mission for why you're embarking on this mushroom journey. Perhaps you're simply driven by curiosity – and that's a fantastic goal as well! Having a clear goal in mind will allow you to sidestep any negative thoughts during unexpected or unpleasant effects, reminding yourself that you have a purpose. Its super simple but so powerful that if I only had a chance to give one advise, here it is.

2. What? (Plan / Setting)

Come up with a simple series of activities – maybe lounging in the park, strolling through a particular neighborhood, or visiting an exhibition. These plans serve as guideposts, but it's crucial not to sweat if things don't go as expected, and everything goes haywire (and it will 😅) Just stay cool.

3. Who? (People.)

Ofcause it's better to do with people you know and trust and great if they already had an experience or ideally have tripsitter experience . But if you want/need to do it alone here is important thing. Social interaction can be intense, especially during the first half of your trip as you're still adjusting to the new state of being. It's best to start somewhere with fewer people and more nature.

4 Where? (Place)

Nature can be ideal but if u are in the city, parks can be a great setting, at least initially. Toward the end, you can venture into more enclosed but fascinating spaces like an art gallery/museum.

5. When? ( Time planning)

The onset usually begins in an hour, but it might take longer. The primary effects last about four hours, followed by a two-hour afterglow. It's best to start no later than midday so that most of the trip is during daylight, making it even more beautiful. Also, don't plan anything else on the day of the trip, and ideally for the next day or at least half of it for processing the experience.

6. How? ( Process)

Avoid eating for three hours beforehand, and stick to light food overall. You'll be ready for a meal afterwards, and you'll instinctively know what to eat. Purchase from a Smart Shop ( if you are in Amsterdam) or from a trusted source and ask for a beginner-friendly strain that prioritizes fun and visual effects over mystical experiences. Desire to disconnect from the internet and your phone as much as possible.

The strains might have a different concentration but usually 1 to 2 gramms could be fine. Over 2.5 you can experience really intense mystical experience and it's not a good idea to do it alone in the city. Decide in the beginning your dose for this trip and stick to the plan, since mushrooms can kick of very unexpectedly the worst you can do is to decide that there is nothing happening and double the dose😅

Good luck and have a safe trip 👌

P.S. Also I'll be happy if you share in comments something that you think is important to add/edit to make this guideline better. Cheers.
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https://www.psypost.org/2023/06/psilocybin-shows-promise-in-ocd-treatment-even-without-the-psychedelic-trip-165645

Why important?

Picture this: you're stuck in a vicious cycle of intrusive thoughts and repetitive behaviors, a nightmarish merry-go-round that's OCD. And then, the knight in shining armor arrives: Psilocybin, with its potential to change the game for OCD treatment, even without making you trip balls

What happened?

Here's the scoop: scientists took mice on a wild ride, tested 'em with a marble-burying task (a stand-in for obsessions, you see). They treated our furry friends with psilocybin and a dose of buspirone to block the psychedelic trip. Guess what? Psilocybin still worked its magic, reducing those frantic marble-burying bebehaviors

How it might be valuable?

This research is like the first step on the moon for OCD treatment! Just imagine, in a world of tomorrow, swallowing a pill of psilocybin, and your obsessive thoughts and behaviors start to fade away, all without you having to take a psychedelic journey.
https://www.nutraingredients-usa.com/Article/2023/06/09/Alkemist-Labs-advances-psychoactive-testing-as-interest-in-psychedelics-grows

Why important?

Well, ever heard of Alkemist Labs? They're like the CSI of dietary supplements, and now they've set their sights on the wild world of psychedelics. Because apparently, we're all getting bored of multivitamins and fish oil, so why not dive into the rabbit hole of mind-altering substances?​

What was done?
In the true spirit of Californian innovation, Alkemist Labs has developed a way to quantify the psychoactive components in plants and fungi. So, basically, they're the equivalent of that friend who claims they can tell exactly how drunk you are just by looking at your eyes, but with, you know, actual science and less slurring.

How it can influence our future?

Picture this: you're at your next house party, taking a shot of your 'special tea' when someone asks, "Hey, how much magic is in this?" Thanks to Alkemist, you'll be able to answer with a precise measurement rather than a vague, "Two scoops of happiness and a pinch of existential dread." Ah, the future: controlled substances and controlled fun, just what we've always dreamed of😁
https://www.psypost.org/2023/06/extensive-study-reveals-new-insights-into-real-world-psychedelic-drug-use-165892


Why?

Pull up a stool, a bunch of researchers decided to take a deep dive into the world of psychedelic drug use in Canada. Their ambition? To understand why people are suddenly so interested in tripping.

What?

They came up with a ridiculously long survey—655 questions—and unleashed it on over 2,000 brave souls who've dabbled in the psychedelic arts. From "Why do you do it?" to "What happened when you did it?", every aspect of the trip was explored, and what they found was that for most, the journey was more about personal growth and exploration than just a wild night out.

How it can help?

That's a biggest Survey so far and can be definitely used for many insights and as with any new niche data you can train an LLM on it and probably find even more exciting outcomes 🤪
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https://www.fda.gov/news-events/press-announcements/fda-issues-first-draft-guidance-clinical-trials-psychedelic-drugs


Why?

Pull up a chair, my friend, because it turns out that psychedelic drugs are now being eyed by the FDA at a new level for their potential to treat conditions like depression and substance use disorders.

What happened?

The FDA, in all its wisdom, has published a draft guidance to provide researchers with the do's and don'ts of designing clinical trials for these psychedelic susubstances. So, instead of "Hey dude, let's try this", it's more like "Please ensure your trial design takes into account the unique characteristics of substances like psilocybin, LSD, and MDMA, and oh, don't forget about potential safety issues and misuse prevention measures"​

How it can change everything?

We could be heading into an era where "trip clinics" are as common as yoga studios, and "serotonin system tweaking" becomes a normal part of wellness routines, all thanks to the FDA opening the door to serious research into these substances.
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https://www.ndtv.com/world-news/in-a-worlds-first-australia-legalises-ecstasy-magic-mushrooms-for-mental-health-4168002

Alright, gather everyone! yesterday we had a very important event.


"Why?" you ask. Well, the folks in Australia have gone bonkers - in a good way. They've legalized ecstasy and magic mushrooms to treat certain mental health disorders​. So, the next time you're feeling a bit down under the weather, you might want to book a flight to Sydney. The Aussies might be onto something here, people!

"What?" Starting from July 1, your friendly neighborhood psychiatrist can now prescribe you some good old MDMA for that PTSD you've been grappling with, or magic mushrooms if you're dealing with some stubborn depression

How you wonder, will this change the future?

Well, brace yourselves for the psychedelic revolution!

​I see a future where mental health treatments are as much a journey of self-discovery as they are about healing. So, here's to Australia, leading us into a future where we embrace the magic in the mushrooms and the ecstasy in MDMA!
https://thedalesreport.com/psychedelics/billionaire-mets-owner-steve-cohen-donates-5m-for-psychedelics-research/


"Why?"

Here's the thing, friends, we've got a billionaire Mets owner, and founder of P72 Ventures ( just recently met some folks form there 😅) Steve Cohen, throwing a hefty $5 million at the psychedelic studies because apparently, just buying a sports team wasn't exciting enough for him.

"What?"

Steve and his better half, Alexandra, are backing MAPS to legitimize the use of MDMA as a therapy for PTSD.

"How?"

This generous donation is aimed at making sure everyone has access to these potentially life-changing therapies, regardless of their financial situation. We might be heading into a brave new world where no one is denied a shot at getting better because they can't afford it. So, cheers to the Cohens for possibly turning the "high" society into a "healed" society!​
Two persons who unsubscribed recently and now it's 98 people instead of 100. You don't understand what you are missing 😈 How Dare you are !!!

For the rest of the amazing creatures, I've prepared a great post about Quarter Flip. Wtf is that you will learn on the weekend 💥

Stay tuned
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Responsible music festivals trip 101

Quarter flip - ideal boost for music festivals. Wtf is that?


Well, I guess most of you heard about LSD and MDMA. So if you mix them together people call it Candy Flip. The effect of this combination is awesome, it's like you are not only mentally in some other beautiful reality if you just have LSD but you also physically feel that you are fully in this reality and you are enjoying it by every cell of your body. Unfortunately there are a number of issues with this combination. First of all it's quite overwhelming mentally and after such an exciting day you may feel really hard "hangover". Secondly in this mood you are extremely subject to bond a very close relationship with a stranger and even fall in love. And finally, well we are not a teenagers ( well, at least I I'm not ), we can't do such experiments even monthly, even quarterly , it's too fucking intense 😅

Also, Candy Flip is actually quite close in it's effect to Mescaline which is somwere between LSD and MDMA but not that intense. That's why it's actually one of the greatest psychedelics for a group gathering. Known and used for ages. But Mescaline is not something that you can find everywhere and it tastes like.... Well bit uncomfortable.

So, why this big into? Well, when you know all disadvantages of a Candy Flip , Mescaline and every other alternative to boost yourself during big rave you know what to search for and how to compare.

Compare with what? With a quarter flip 🤪 my own patented combination ( joking) hmm.... But why not,... Anyway:

Quarter Flip it nothing more than a 1/4 of a candy flip, but! Despite it's super simple idea it turned out to be an amazing combination.

Technically it's a mix of 50mkg of LSD and 50mg of MDMA. Both are low doses according to Psychonautwiki but are at least 2 times abowe the treshhold

Ok long story short, here are the Advantages specifically comparing to any other options you will use to have fun during 6-8 hours festival where you want to get maximum of it.


Advantages:

- haven't had a single thought about alcohol or weed ( usually you need a lot of it to stay 8 hours alive and few extra redbuls )
- almost no uncomfortable physical side effects like you either want to drink or pee every 30 min ( comparing to any regular dose of any party drug )
- Don't have deep exidistential thoughts or unexpected breakthrough experience in the middle of the dancefloor ( comparing to full dose LSD or Shrooms)
- can experience full emotional release by dancing as hell and being in the moment by just laying on the ground to relax between dj sets
- can experience absolute calm and relaxation and meditative state of mind when you are enjoying this absolute nothing.
- everything is a bit more interesting but not completely wired comparing to regulate psychedelic dose
- feel more comfortable with police/guard comparing to full dose of Psychedelics
- can want and have sex ( comparing to full dose LSD when you don't care about those "stupid carnal pleasures" )
- and more importantly can finish it (comparing to regular MDMA dose 😅)
- less chance to fall into deeper connection with unexpected person and ruine few months of your life
- and finally you almost don't have any side effects z downs, hangovers and so on.

Well it was really quite hard to find some disadvantages but here they are:


- A bit harder to react to the fast music changes and feel it fully comparing to alco/MDMA/weed

- You are still not really feel to hangout with new people so of it's your goal you can maybe add but more MDMA but you are absolutely comfortable to be surrounded by people while if you just have quarter of LSD sometimes you just want to leave the festival and hug trees 😅

- Finally the biggest issue is that this experience can give you a feeling that WTF am I not doing this every week , so if you will try it try responsibly and always have at least 1 Month pause.

Well, I hope you enjoyed and if you want to read more "research" like this, put some emoji 🙊

Have a great weekend 👌
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https://psychedelicspotlight.com/inside-ibogaine-the-overlooked-yet-promising-psychedelic-for-addiction-recovery/


Why important?

Well, my dear friends, in our world where addiction is as common as a Kardashian on Instagram, ibogaine is a psychedelic that's been overlooked for far too long. It's like the nerdy kid at school who turns out to be a genius - it has the potential to revolutionize addiction treatment, but it's been sitting quietly in the corner while the cool kids like LSD and psilocybin get all the attention.

What was done?

They're not just throwing chemicals around willy-nilly, they're conducting rigorous studies, showing that ibogaine can reduce withdrawal symptoms and cravings, and even reset the brain's addiction pathways. It's like hitting the reset button on your computer when it starts acting up, but for your brain.

How it can change the future?

Picture this: a world where addiction isn't a life sentence, but something you can hit the reset button on. Now, isn't that a future worth toasting to?
Scientists found where brain triggers out-of-body experiences


https://www.wsiu.org/2023-07-06/scientists-have-found-part-of-the-brain-that-triggers-out-of-body-experiences



Why important?

Well, my dear friends, it seems that scientists have finally pinpointed a part of the brain that triggers out-of-body experiences, a phenomenon that has baffled us for centuries. This discovery could potentially revolutionize our unders tanding of consciousness and self-perception.

What was done? In a nutshell, Dr. Josef Parvizi and his team at Stanford stimulated a sausage-shaped part of the brain called the anterior precuneus in eight patients. Lo and behold, each patient experienced changes in their sense of physical self, feeling as though they were floating or freefalling.

How it can change the future? Picture this: we could potentially manipulate our sense of self and consciousness, maybe even create virtual reality experiences without the need for those clunky headsets. Or perhaps, we could develop new treatments for mental health disorders, providing relief for those suffering from severe depression or anxiety.
Psychedelic Consciousness ( ex Unstoppable Technologies) pinned «Responsible music festivals trip 101 Quarter flip - ideal boost for music festivals. Wtf is that? Well, I guess most of you heard about LSD and MDMA. So if you mix them together people call it Candy Flip. The effect of this combination is awesome, it's like…»
Invest in Psychedelics or die trying ;)

Investors are now giddy like schoolchildren at the thought of magic mushrooms being used in therapy. Big names in the business world are taking notice, and the psychedelic industry is poised to become a billion-dollar market. So, what was once an excuse to listen to The Grateful Dead and eat pizza is now a therapy option for mental health. Who knew, right?

Now, some folks are even bold enough to say that psychedelic-assisted therapy is the future of mental health treatment. So, you might be getting your stock tips from someone who just got out of a session with a psychedelic toad. A word of caution, though: while psychedelic stocks might look like the golden ticket, remember, it's still a fledgling market, and not everyone's going to be the next Steve Jobs of psychedelics.

So there you have it. The lowdown on the upswing of psychedelic investments. If you ever wanted to invest in Alice's trip down the rabbit hole, now might be your chance.

Well I've actually done it already and invested few years ago in the world first psychedelic IPO of Compass Pathways and made 3x in one day 😅

https://seekingalpha.com/article/4615975-psychedelics-gaining-acceptance-what-does-it-mean-for-investors?source=feed_all_articles
$100m in Psychedelics research, suck it, AI 😅

Alright, folks, Blake Mycoskie, the Toms Shoes guy, is now investing $100 million into psychedelic research. Yes, you heard right, the shoe philanthropist is now a psychedelic philanthropist.

Apparently, he had a personal crisis, tried ayahuasca, and it worked wonders for him. Now he's hoping his donation will bring these alternative treatments into the mainstream. Who's is next ;)?

https://www.newsweek.com/donating-psychedelics-research-philanthropy-1811505
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One more lab joining DMTX project with $1.5m donation.

UC San Diego research team will implement continuous intravenous DMT infusion protocols to capture what is known as the “extended state” of visions long associated with DMT.

"Our goals are to employ multi-modal approaches to study extended state consciousness elucidated by DMT to further appreciate the nature of reality as well as the role of endogenous DMT in the human body. Reliable methods for measuring DMT directly in the human brain and bodily fluids do not exist, so the intriguing possibilities that endogenous DMT may play a role in consciousness, dreaming and protecting the brain from trauma are still scientific speculation,” said Dean


https://today.ucsd.edu/story/1.5-million-donation-supports-research-on-effects-of-psychedelic-dmt-on-the-brain
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