Ukraine is moving to right direction 🔥
Well it's in the government level now, looks very promising.
“Today we have 13 trauma therapists who can work with psychedelic assisted therapy. … We need 300,”
Quote 1:
“We have this catastrophic challenge ahead,” Dmytro Gurin, a Ukrainian MP in President Volodymyr Zelenskyy's Servant of the People party and member of the country’s health committee, told a meeting of MEPs at the European Parliament on Tuesday. “And such challenges, they need bold decisions.”
Quote 2:
"Gurin is pitching that Ukraine's large population of trauma sufferers means the country could become a research center for MDMA-assisted therapies. He'd like EU financial support for Ukraine to develop a nationwide clinical trial to test MDMA-assisted therapy as a first treatment for trauma, rather than as a last resort, as is normally recommended.
Quote 3:
His solution is to set up a training center in the safe city of Uzhhorod, which borders Slovakia. From here, he said, Ukrainian therapists can be trained for Ukrainian cases: understanding the tortures and traumas of war.
https://www.politico.eu/article/ukraine-mp-dmytro-gurin-test-psychedelics-ptsd/
Well it's in the government level now, looks very promising.
“Today we have 13 trauma therapists who can work with psychedelic assisted therapy. … We need 300,”
Quote 1:
“We have this catastrophic challenge ahead,” Dmytro Gurin, a Ukrainian MP in President Volodymyr Zelenskyy's Servant of the People party and member of the country’s health committee, told a meeting of MEPs at the European Parliament on Tuesday. “And such challenges, they need bold decisions.”
Quote 2:
"Gurin is pitching that Ukraine's large population of trauma sufferers means the country could become a research center for MDMA-assisted therapies. He'd like EU financial support for Ukraine to develop a nationwide clinical trial to test MDMA-assisted therapy as a first treatment for trauma, rather than as a last resort, as is normally recommended.
Quote 3:
His solution is to set up a training center in the safe city of Uzhhorod, which borders Slovakia. From here, he said, Ukrainian therapists can be trained for Ukrainian cases: understanding the tortures and traumas of war.
https://www.politico.eu/article/ukraine-mp-dmytro-gurin-test-psychedelics-ptsd/
POLITICO
Ukrainian MP tells MEPs country should be test bed for psychedelics – POLITICO
Dmytro Gurin said that therapies based on drugs such as MDMA could treat soaring rates of post-traumatic stress disorder.
🥰2
Ketamine for heartbreak and Burnout
Sold😁
Shut up and take my money 🤑
"Emotional wounds like rejection and failure can be even more devastating than physical wounds, yet we don't give them the same time and attention,"
"I'm thrilled to combine my techniques for emotional first aid with ketamine therapy, which has been shown to increase neuroplasticity and help build emotional resilience"
Want some K therapy ? 😃
https://www.prnewswire.com/news-releases/mindbloom-launches-expert-led-psychedelic-therapy-for-heartbreak-burnout-and-more-302000235.html
Sold😁
Shut up and take my money 🤑
"Emotional wounds like rejection and failure can be even more devastating than physical wounds, yet we don't give them the same time and attention,"
"I'm thrilled to combine my techniques for emotional first aid with ketamine therapy, which has been shown to increase neuroplasticity and help build emotional resilience"
Want some K therapy ? 😃
https://www.prnewswire.com/news-releases/mindbloom-launches-expert-led-psychedelic-therapy-for-heartbreak-burnout-and-more-302000235.html
PR Newswire
Mindbloom Launches Expert-Led Psychedelic Therapy for Heartbreak, Burnout, and more
/PRNewswire/ -- Mindbloom, the largest provider of psychedelic medicine, today announced the launch of its Mastermind Series – the first expert-led psychedelic...
Podcast on MDMA therapy and more
Very insightful podcast with one of the "OG"'s of psychedelic therapy.
Some notes:
Trauma's have different effects (and approachesbto cure) at different ages
Ifs, and EMDR are the best psychotherapy methods so far before psychedelics
DSM was just created to somehow test drug research and should not be used as a diagnosis
MDMA therapy also make you less tolerant to what you think other people think of you
MDMA help people to be less identified with trauma. Instead of "I'm a Vietnam veteran" -> "I'm a human being experienced complex event."
MDMA therapy model super promising but practically very expensive( 36 hours of therapist's total) and may be not scalable.
Group therapy with Ketamine might have more potential in reality for broader accessibility
Somatic self awareness ( mind-body connection) in 2 days before therapy can significantly decrease the dose especially for people who have low mind body connection.
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5saWJzeW4uY29tLzgxODk1L3Jzcw/episode/NmU2NzNlNzQtZTZhYy00NWZiLTk3MWQtNWJlYTBhZDNjODg3?ep=14
Very insightful podcast with one of the "OG"'s of psychedelic therapy.
Some notes:
Trauma's have different effects (and approachesbto cure) at different ages
Ifs, and EMDR are the best psychotherapy methods so far before psychedelics
DSM was just created to somehow test drug research and should not be used as a diagnosis
MDMA therapy also make you less tolerant to what you think other people think of you
MDMA help people to be less identified with trauma. Instead of "I'm a Vietnam veteran" -> "I'm a human being experienced complex event."
MDMA therapy model super promising but practically very expensive( 36 hours of therapist's total) and may be not scalable.
Group therapy with Ketamine might have more potential in reality for broader accessibility
Somatic self awareness ( mind-body connection) in 2 days before therapy can significantly decrease the dose especially for people who have low mind body connection.
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5saWJzeW4uY29tLzgxODk1L3Jzcw/episode/NmU2NzNlNzQtZTZhYy00NWZiLTk3MWQtNWJlYTBhZDNjODg3?ep=14
Google Podcasts
Psychedelics Today - PT464 – Bessel van der Kolk, MD – Bodywork, Somatic Literacy, and Understanding Trauma: The Mind and Body…
In this episode, Kyle interviews Bessel van der Kolk, MD: pioneer clinician, researcher, and educator on traumatic stress; Founder of the Trauma Research Foundation; Professor of Psychiatry at Boston University Medical School; Principal Investigator of the…
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Curious to see more research on therapy applications and comparison with MDMA.
https://youtu.be/UAykz73MdsA?si=TBZZhQHr59foAgJS
https://youtu.be/UAykz73MdsA?si=TBZZhQHr59foAgJS
YouTube
3-MMC: The Party Drug Taking Europe by Storm | High Society
Europe is undergoing a synthetic boom, with hundreds of stimulants springing up across the continent. None though are creating quite as much buzz as 3-MMC. Piggybacking into the party scene off its predecessor Mephedrone, 3-MMC (3-methylmethcathinone) offers…
A new type of Psilocybin
So what is Drysdale’s secret weapon to bring even more therapeutic value to psilocybin? It’s a process called deuteration. It focuses on the hydrogen atoms in psilocybin. These atoms are very light and don’t stick very well to carbon, which is another atom in psilocybin. As a result, our bodies can easily breaks down the bonds between the hydrogen and carbon atoms. For many people, that means psilocybin gets cleared from the body too quickly, before it can have a therapeutic benefit.
In deuteration, scientists do something simple but ingenious: they replace the hydrogen atoms with a molecule called deuterium. It’s twice as heavy as hydrogen and forms tighter bonds with the carbon. Because these pairs are so rock-steady, they slow down the rate at which psilocybin is metabolized, so it has more sustained effects on our brains.
https://leaps.org/psilocybin/particle-1
So what is Drysdale’s secret weapon to bring even more therapeutic value to psilocybin? It’s a process called deuteration. It focuses on the hydrogen atoms in psilocybin. These atoms are very light and don’t stick very well to carbon, which is another atom in psilocybin. As a result, our bodies can easily breaks down the bonds between the hydrogen and carbon atoms. For many people, that means psilocybin gets cleared from the body too quickly, before it can have a therapeutic benefit.
In deuteration, scientists do something simple but ingenious: they replace the hydrogen atoms with a molecule called deuterium. It’s twice as heavy as hydrogen and forms tighter bonds with the carbon. Because these pairs are so rock-steady, they slow down the rate at which psilocybin is metabolized, so it has more sustained effects on our brains.
https://leaps.org/psilocybin/particle-1
leaps.org
Stronger psychedelics that rewire the brain, with Doug Drysdale
A promising development in science in recent years has been the use technology to optimize something natural. One-upping nature's wisdom isn't easy. In many cases, we haven't - and maybe we can't - figure it out. But today's episode features a fascinating…
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Beta-carbolines - WTF?
You always leaning... I thought I Know at least most of the classes of Psychedelic compounds but here we are, another category that was new for me - beta-carbolines. I knew that it's a part of original Ayahuasca but haven't paid much attention yet.
For me the most important is that they have effects exactly what I was looking for! Something that can help you to change your state into more calm and meditative but just a little bit. Weed and Ketamine are capable of doing it but still have other side effects for this particular task .
I wish that beta-carbolines are exactly what i was looking for. Will try 😁
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5saWJzeW4uY29tLzgxODk1L3Jzcw/episode/ZDliNjZlNjUtMTg2Yi00NTQxLWEzOTItMDg3NTk2YTkyYzM2?ep=14
You always leaning... I thought I Know at least most of the classes of Psychedelic compounds but here we are, another category that was new for me - beta-carbolines. I knew that it's a part of original Ayahuasca but haven't paid much attention yet.
For me the most important is that they have effects exactly what I was looking for! Something that can help you to change your state into more calm and meditative but just a little bit. Weed and Ketamine are capable of doing it but still have other side effects for this particular task .
I wish that beta-carbolines are exactly what i was looking for. Will try 😁
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5saWJzeW4uY29tLzgxODk1L3Jzcw/episode/ZDliNjZlNjUtMTg2Yi00NTQxLWEzOTItMDg3NTk2YTkyYzM2?ep=14
Google Podcasts
Psychedelics Today - PT465 – Shauheen Etminan, Ph.D. & Jonathan Lu – Beta-carbolines, Haoma, and Syrian Rue: Rediscovering Ancestral…
In this episode, David interviews Shauheen Etminan, Ph.D. and Jonathan Lu: Co-Founders of Magi Ancestral Supplements.
Through studying ancient Zoroastrian writings and 2,000 year-old Chinese texts in search of compounds and formulations forgotten by history…
Through studying ancient Zoroastrian writings and 2,000 year-old Chinese texts in search of compounds and formulations forgotten by history…
👍1
Woooot😁
If all goes well, it’s possible that FDA approval for the prenoscription use of MDMA-assisted therapy for PTSD could take place around August 2024, with DEA rescheduling legally required to take place within 90 days after FDA approval
https://microdose.buzz/news/breaking-news-maps-files-new-drug-application-with-fda-for-mdma-assisted-therapy/
If all goes well, it’s possible that FDA approval for the prenoscription use of MDMA-assisted therapy for PTSD could take place around August 2024, with DEA rescheduling legally required to take place within 90 days after FDA approval
https://microdose.buzz/news/breaking-news-maps-files-new-drug-application-with-fda-for-mdma-assisted-therapy/
Microdose
Breaking News: MAPS Files New Drug Application With FDA for MDMA-Assisted Therapy
Historic filing marks first New Drug Application submission for any psychedelic-assisted therapy
Hey fellow founders we have a "prenoscription"
"Investor Eddy Vaisberg, 33, told Business Insider ayahuasca could help founders gain better insights into themselves and others — and boost their creativity.
Thank you, mister investor, we know 😂, it can also help founders to quit this rat race ;) be careful.
https://www.businessinsider.com/psychedelic-tea-ayahuasca-effects-founders-experiment-better-leaders-1heart-2023-12
"Investor Eddy Vaisberg, 33, told Business Insider ayahuasca could help founders gain better insights into themselves and others — and boost their creativity.
Thank you, mister investor, we know 😂, it can also help founders to quit this rat race ;) be careful.
https://www.businessinsider.com/psychedelic-tea-ayahuasca-effects-founders-experiment-better-leaders-1heart-2023-12
Business Insider
Why one investor thinks founders looking to boost creativity should try this controversial method
A VC thinks founders should consider using a psychedelic drink. The idea of mind-altering substances is controversial. Just ask Elon Musk.
😁4❤3
79% success in Psilocybin for MDD
Cybin published results of phase 2 for curing Major Depressive Disorder with its own Psilocybin derivative CYB003.
"Next on the list for Cybin is submitting it to the FDA and requesting the federal agency an end-of-Phase 2 meeting for Q1 2024. With additional 12-week durability data from the Phase 2 study expected by next Q1 as well, Cybin anticipates -approval pending- to start recruiting for the Phase 3 study by the end of Q1 2024."
Seems like MDMA will be finally prescribed in 2024 and Psilocybin more likely will hit the market in 2025.
https://www.benzinga.com/markets/cannabis/23/12/36055625/cybins-novel-psilocybin-topline-data-79-remission-in-major-depression-symptoms-whats-next
Cybin published results of phase 2 for curing Major Depressive Disorder with its own Psilocybin derivative CYB003.
"Next on the list for Cybin is submitting it to the FDA and requesting the federal agency an end-of-Phase 2 meeting for Q1 2024. With additional 12-week durability data from the Phase 2 study expected by next Q1 as well, Cybin anticipates -approval pending- to start recruiting for the Phase 3 study by the end of Q1 2024."
Seems like MDMA will be finally prescribed in 2024 and Psilocybin more likely will hit the market in 2025.
https://www.benzinga.com/markets/cannabis/23/12/36055625/cybins-novel-psilocybin-topline-data-79-remission-in-major-depression-symptoms-whats-next
Benzinga
Cybin's Novel Psilocybin Topline Data: 79% Remission In Major Depression Symptoms, What's Next? - Cybin (AMEX:CYBN)
Next-generation psychedelics biotech Cybin Inc. (NYSE: CYBN) released the full Phase 2 trial results of its deuterated psilocybin derivative CYB003 for Major Depressive Disorder (MDD.) Although a relatively small trial, outcomes for the novel psychedelic…
🥰2
Psychedelic Apps market
I know what you will do during Christmass holidays. 🤣
List of Prominent Players in the Mental Health Psychedelic Apps Market:
• Field Trip Health
• Mindleap,
• Homecoming
• Mindbloom,
• Microdose.me,
• Polyfauna, PsycheDev
• Wavepaths
• TripApp
• Hypnoglyph
• Fraksl ,
• Lumenate
• Last Voyage
• PsyStation
https://www.openpr.com/news/3313112/mental-health-psychedelic-apps-market-latest-trends-and-future
I know what you will do during Christmass holidays. 🤣
List of Prominent Players in the Mental Health Psychedelic Apps Market:
• Field Trip Health
• Mindleap,
• Homecoming
• Mindbloom,
• Microdose.me,
• Polyfauna, PsycheDev
• Wavepaths
• TripApp
• Hypnoglyph
• Fraksl ,
• Lumenate
• Last Voyage
• PsyStation
https://www.openpr.com/news/3313112/mental-health-psychedelic-apps-market-latest-trends-and-future
openPR
Mental Health Psychedelic Apps Market Latest Trends and Future Opportunities Analysis to 2031
InsightAce Analytic Pvt Ltd announces the release of a market assessment report on the Global Mental Health Psychedelic Apps Market By Therapy Type Music Creative Artistic Visual Patterns Puzzle Guidance Lifestyle By O S Type Android iOS iOS Trends Industry…
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Neural Geometrodynamics
This research delves into a novel concept called "neural geometrodynamics," drawing parallels with general relativity in understanding the brain's functioning, particularly under the influence of psychedelics.
It focuses on three key timescales in the brain:
Fast Time Dynamics: These are immediate neural activities governed by differential equations and connectivity parameters. Think of this as the brain's immediate response to stimuli.
Slow Time Dynamics: Over this longer period, the brain's connectivity changes due to plasticity mechanisms. This is akin to the brain learning or adapting based on experiences.
Ultraslow Time Dynamics: This is where metaplasticity occurs - the brain's ability to change how it changes. It's a higher level of adaptation and learning.
Psychedelics, interestingly, flatten the brain's neural landscape. This flattening leads to a more chaotic and complex state of neural dynamics, as evidenced by neuroimaging studies.
https://www.biorxiv.org/content/10.1101/2023.08.14.553258v2
This research delves into a novel concept called "neural geometrodynamics," drawing parallels with general relativity in understanding the brain's functioning, particularly under the influence of psychedelics.
It focuses on three key timescales in the brain:
Fast Time Dynamics: These are immediate neural activities governed by differential equations and connectivity parameters. Think of this as the brain's immediate response to stimuli.
Slow Time Dynamics: Over this longer period, the brain's connectivity changes due to plasticity mechanisms. This is akin to the brain learning or adapting based on experiences.
Ultraslow Time Dynamics: This is where metaplasticity occurs - the brain's ability to change how it changes. It's a higher level of adaptation and learning.
Psychedelics, interestingly, flatten the brain's neural landscape. This flattening leads to a more chaotic and complex state of neural dynamics, as evidenced by neuroimaging studies.
https://www.biorxiv.org/content/10.1101/2023.08.14.553258v2
bioRxiv
Neural geometrodynamics, complexity, and plasticity: a psychedelics perspective
We explore the intersection of neural dynamics and the effects of psychedelics in light of distinct timescales in a framework integrating concepts from dynamics, complexity, and plasticity. We call this framework neural geometrodynamics for its parallels…
Psychedelics as a Possible Cure for Color Blindness
Psilocybin may have temporarily modified the way color-blind patients perceive color. The data comes from a case report and the 2017 Global Drug Survey, although both studies have their flaws.
This phenomenon needs further investigation to determine its potential.
The subject had taken the Ishihara test, which consists of 21 plates with colored dots arranged in patterns to form numbers, before taking his initial dose. He scored 14 out of 21, indicating mild color blindness. He proceeded to retest himself 12 and 14 hours after consuming 5 grams of mushrooms scoring 15 the first time and 18 the second time.
A score above 17 indicates normal vision, suggesting that he recovered his ability to distinguish colors.
He retested himself eight days after his trip, scoring 19, and four months later, bumping down to 18 again.
https://psychedelicspotlight.com/why-do-we-feel-like-we-can-score-40-20-in-visual-acuity-on-low-doses-of-psychedelics/
Psilocybin may have temporarily modified the way color-blind patients perceive color. The data comes from a case report and the 2017 Global Drug Survey, although both studies have their flaws.
This phenomenon needs further investigation to determine its potential.
The subject had taken the Ishihara test, which consists of 21 plates with colored dots arranged in patterns to form numbers, before taking his initial dose. He scored 14 out of 21, indicating mild color blindness. He proceeded to retest himself 12 and 14 hours after consuming 5 grams of mushrooms scoring 15 the first time and 18 the second time.
A score above 17 indicates normal vision, suggesting that he recovered his ability to distinguish colors.
He retested himself eight days after his trip, scoring 19, and four months later, bumping down to 18 again.
https://psychedelicspotlight.com/why-do-we-feel-like-we-can-score-40-20-in-visual-acuity-on-low-doses-of-psychedelics/
Psychedelic Spotlight
Why Do We Feel Like We Can Score 40/20 in Visual Acuity on Low Doses of Psychedelics?
One possible reason for this phenomenon is psilocybin’s interaction with the thalamus, the section of our brain that receives sensory information an
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Breaking: Ukraine legalized medical Cannabis
I believe MDMA will be the next step very soon
https://www.bloomberg.com/news/articles/2023-12-21/ukraine-moves-to-legalize-medical-marijuana-to-treat-veterans
I believe MDMA will be the next step very soon
https://www.bloomberg.com/news/articles/2023-12-21/ukraine-moves-to-legalize-medical-marijuana-to-treat-veterans
Bloomberg.com
Ukraine Moves to Legalize Medical Marijuana to Treat Veterans
Ukraine’s parliament approved the legalization of medical cannabis as the nation responds to the growing ranks of war veterans requiring treatment for injuries and post-traumatic stress disorder.
🔥3👍1
New Psychedelic Chatbot
Woooot, one more Chatbot for Psychonauts just released by Josie Kins. Great move towards harm reduction.
It can help to get proper information on substance usage. Examples in the comments, please share yours.
https://www.psyai.chat/
Woooot, one more Chatbot for Psychonauts just released by Josie Kins. Great move towards harm reduction.
It can help to get proper information on substance usage. Examples in the comments, please share yours.
https://www.psyai.chat/
psyai.chat
PsyAIᵃˡᵖʰᵃ - Harm Reduction Chat
Educational substance harm reduction information using AI.
❤2
Maybe Stop milking toads ?
We have a synthetic version of 5 MEO-DMT. Why are we still torturing those beautiful spicies?
https://www.vice.com/en/article/pkawev/mexican-cartels-dmt-psychedelic-bufo-alvarius-toad-hunters
We have a synthetic version of 5 MEO-DMT. Why are we still torturing those beautiful spicies?
https://www.vice.com/en/article/pkawev/mexican-cartels-dmt-psychedelic-bufo-alvarius-toad-hunters
VICE
Psychedelic Toad Hunters Are Under Attack by Mexican Cartels
Those making a living off harvesting the potent venom of the Sonoran desert toad are getting caught in the crossfire of narco traffickers.
🔥1
Psychedelic Consciousness ( ex Unstoppable Technologies) pinned «Responsible mind altering 101 1. Chose the state of mind you want to achieve An excellent source to understand it at a high level is this chart: https://www.zazzle.com/psycotropic_drug_chart-228428078473759284 2. Understand the dosage, effects, after…»
Happy new year 😊
"Using MDMA therapy, she broke through the feeling that she needed to be perfect to deserve to exist. "
We all deserve it without struggle 🥰
https://www.businessinsider.com/mdma-therapy-helped-oil-heir-koch-overcome-buried-pain-2023-11
"Using MDMA therapy, she broke through the feeling that she needed to be perfect to deserve to exist. "
We all deserve it without struggle 🥰
https://www.businessinsider.com/mdma-therapy-helped-oil-heir-koch-overcome-buried-pain-2023-11
Business Insider
The daughter of multi-millionaire oil tycoon Charles Koch thought she had to be liked to deserve to exist, until MDMA therapy
Elizabeth Koch, who's tied to conservative causes through her fathers conglomerate, invests in MDMA therapy. Rachel Nuwer tells why in her new book.
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Responsible Kratom usage 101
Why Kratom?
I'm constantly looking for substances that can be used instead of alcohol that can bring more energy and make social interactions easier and Kratom looks promising and getting quite popular in the US.
What is Kratom?
Yet another leaves from Coffe family, popular in Southeast Asia, especially in Thailand.
Subjective effects include sedation, stimulation, pain relief, anxiety suppression, muscle relaxation, and euphoria.
Kratom have a lot of strains that either can be more energetic or more relaxing. Usually lover doses work like caffeine-like stimulant , higher dosed more like opioid pain relief and euphoria.
Particular strains:
Red Vein: sedating and relaxing, better suited for managing insomnia or pain.
Gold/Yellow Vein: have a variety of effects depending on the vendor
Green Vein: Green vein effects are a mix between white and red.
White Vein: Leaves with a white vein are reported to be energetic and stimulating, promoting alertness, motivation, and wakefulness in low to moderate doses
How does it work?
In more details it works in at least 3 directions:
1. Mitragynine and 7-hydroxymitragynine bind as partial agonists to the μ-opioid receptors and antagonistic to the κ- and δ-opioid receptors.
2. Agonist to norepinephrine and serotonin receptor systems where it functions as an agonist.
3.Kratom contains the alkaloid rhynchophylline, which functions as an NMDA receptor antagonist.This may be responsible for the mild dissociating effects which occur at heavy doses.
So, how much is not too much?
Well it depends 😅
Usually it looks like this:
Pain Relief - starting with 2-4 grams and up to 5 grams or more produce the most effective relief.
Energy & Focus - Most people don't need more than 2-4 grams.
Opiate Withdrawal - most people require a higher-than-average dose—5 grams or more
Anxiety - When treating anxiety, higher doses are typically preferred 3-4 grams
Depression - The most typical dose for mild depression is 1-2 grams.
But who da hell knows how much is in your drink😅
There is a hipster version in some weed shops in Thailand with 3 types of bottles, strong, medium, light. If you take one of them, even strong it's totally ok for energy/focus
If you can only find some local mix usually sold in 1.5l bottle, it's ok to take not more than 500ml(man) 300-400ml(woman).
More on dosage:
https://kratom.org/guides/dosage/
Kratom Mixing
Unfortunately most of the drug mixing tables don't have Kratom so here is my personal take:
You can mix it with alcohol, just like a a red bull. But only with a small dosage of Kratom
If you mix it with weed the effects can be quite nice, however Avoid mixing with Weed in high doses!
More on mixing:
https://www.apotheca.org/blog/mixing-kratom-and-marijuana
Kratom side effects !!!
There is one thing very important to note.Dosage
More than 580 people in Florida have died from kratom-related overdoses during the past decade.
Kratom can come with very brutal side effects if:
1.High doses
2.Mixed with weed
3.You are a woman (sorry 😅)
4.Any combination of above
You can experience nausea and in worst case it can last for 2 days
If you have nausea, and you are in Thailand u can use "flying white rabbit" mix or any other medication.
In order to avoid side effects its better to prepare before:
https://www.zamnesia.com/blog-how-to-prevent-kratom-nausea-n1056
Summary:
I'm not promoting it, but if taken in low doses it might be quite fun and interesting, but in medium/high the side effects can be more than those from traditional stimulants and euphoretics but with less actual positive effects.
Read more about psychedelics: @unstoppable_technologies
Other sources
1. Kratom for pain https://www.novusfumus.nl/en/smartshop/herbs-and-supplements/kratom/karatom-nausea/
2. Kratom legislation
https://www.tampabay.com/investigations/2023/12/30/5-ways-make-kratom-marketplace-safer/
3. Great podcast
https://www.plantmedicine.org/podcast/kratom-research-and-use-dr-oliver-grundmann
Why Kratom?
I'm constantly looking for substances that can be used instead of alcohol that can bring more energy and make social interactions easier and Kratom looks promising and getting quite popular in the US.
What is Kratom?
Yet another leaves from Coffe family, popular in Southeast Asia, especially in Thailand.
Subjective effects include sedation, stimulation, pain relief, anxiety suppression, muscle relaxation, and euphoria.
Kratom have a lot of strains that either can be more energetic or more relaxing. Usually lover doses work like caffeine-like stimulant , higher dosed more like opioid pain relief and euphoria.
Particular strains:
Red Vein: sedating and relaxing, better suited for managing insomnia or pain.
Gold/Yellow Vein: have a variety of effects depending on the vendor
Green Vein: Green vein effects are a mix between white and red.
White Vein: Leaves with a white vein are reported to be energetic and stimulating, promoting alertness, motivation, and wakefulness in low to moderate doses
How does it work?
In more details it works in at least 3 directions:
1. Mitragynine and 7-hydroxymitragynine bind as partial agonists to the μ-opioid receptors and antagonistic to the κ- and δ-opioid receptors.
2. Agonist to norepinephrine and serotonin receptor systems where it functions as an agonist.
3.Kratom contains the alkaloid rhynchophylline, which functions as an NMDA receptor antagonist.This may be responsible for the mild dissociating effects which occur at heavy doses.
So, how much is not too much?
Well it depends 😅
Usually it looks like this:
Pain Relief - starting with 2-4 grams and up to 5 grams or more produce the most effective relief.
Energy & Focus - Most people don't need more than 2-4 grams.
Opiate Withdrawal - most people require a higher-than-average dose—5 grams or more
Anxiety - When treating anxiety, higher doses are typically preferred 3-4 grams
Depression - The most typical dose for mild depression is 1-2 grams.
But who da hell knows how much is in your drink😅
There is a hipster version in some weed shops in Thailand with 3 types of bottles, strong, medium, light. If you take one of them, even strong it's totally ok for energy/focus
If you can only find some local mix usually sold in 1.5l bottle, it's ok to take not more than 500ml(man) 300-400ml(woman).
More on dosage:
https://kratom.org/guides/dosage/
Kratom Mixing
Unfortunately most of the drug mixing tables don't have Kratom so here is my personal take:
You can mix it with alcohol, just like a a red bull. But only with a small dosage of Kratom
If you mix it with weed the effects can be quite nice, however Avoid mixing with Weed in high doses!
More on mixing:
https://www.apotheca.org/blog/mixing-kratom-and-marijuana
Kratom side effects !!!
There is one thing very important to note.
More than 580 people in Florida have died from kratom-related overdoses during the past decade.
Kratom can come with very brutal side effects if:
1.High doses
2.Mixed with weed
3.You are a woman (sorry 😅)
4.Any combination of above
You can experience nausea and in worst case it can last for 2 days
If you have nausea, and you are in Thailand u can use "flying white rabbit" mix or any other medication.
In order to avoid side effects its better to prepare before:
https://www.zamnesia.com/blog-how-to-prevent-kratom-nausea-n1056
Summary:
I'm not promoting it, but if taken in low doses it might be quite fun and interesting, but in medium/high the side effects can be more than those from traditional stimulants and euphoretics but with less actual positive effects.
Read more about psychedelics: @unstoppable_technologies
Other sources
1. Kratom for pain https://www.novusfumus.nl/en/smartshop/herbs-and-supplements/kratom/karatom-nausea/
2. Kratom legislation
https://www.tampabay.com/investigations/2023/12/30/5-ways-make-kratom-marketplace-safer/
3. Great podcast
https://www.plantmedicine.org/podcast/kratom-research-and-use-dr-oliver-grundmann
Kratom.org
Kratom Dosage Guide — How Much Kratom Should I Take? - Kratom.org
The standard dosage range for kratom is 2 to 8 grams. Low doses are stimulating; higher doses are sedative. But there's more you should know.
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MAPS now Lykos Therapeutics
MAPS looking more and more like OpenAI with its nonprofit/for profit structure and now the recent 100m$ series A round😱
https://maps.org/2024/01/05/maps-welcomes-new-investors-name-change-for-maps-public-benefit-corporation/?utm_source=pardot&utm_medium=email&utm_campaign=2024-bau&utm_content=Lykos%20announcement
MAPS looking more and more like OpenAI with its nonprofit/for profit structure and now the recent 100m$ series A round😱
https://maps.org/2024/01/05/maps-welcomes-new-investors-name-change-for-maps-public-benefit-corporation/?utm_source=pardot&utm_medium=email&utm_campaign=2024-bau&utm_content=Lykos%20announcement
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Elon Musk Has Used Illegal Drugs, Worrying Leaders at Tesla and SpaceX - WSJ
Not surprised. But jokes aside, this can be a very important moment for psychedelics future depending on how the world ( shareholders mainly) will react on it.
https://www.wsj.com/business/elon-musk-illegal-drugs-e826a9e1
Not surprised. But jokes aside, this can be a very important moment for psychedelics future depending on how the world ( shareholders mainly) will react on it.
https://www.wsj.com/business/elon-musk-illegal-drugs-e826a9e1
The Wall Street Journal
Elon Musk Has Used Illegal Drugs, Worrying Leaders at Tesla and SpaceX
Some executives and board members fear the billionaire’s use of drugs—including LSD, cocaine, ecstasy, mushrooms and ketamine—could harm his companies.