EMDR + Psychedelics = Match
First I thought -WTF, those are 2 very powerful instruments. why mixng?
Then I remember myself trying to do that with Ketamine long time ago with the idea that it might help me to enter the EMDR season and get rid of the blocks i had, but my experiment was not successful that time.
So how we can mix EMDR with psychedelics?
1. As a preparation session before to get to trauma
2. As a tool to get out from repeating loop happening during psychedelic therapy (research in going on in this area)
3. As a better way to use neuroplasticity window after psychedelic to run even better integration
4. Microdosing to enhance EMDR
What are the combinations
1. EMDR + weed to increase body connection
2. EMDR + MDMA - perfect match
3. EMDR + Ketamine - there is a research that it's actually make sense in low doses (maybe I need to try again)
4. EMDR + Classic Psychedelic - great too to process and integrate all insights clothes to the end of trip
P.S. there was a short conversation on flashbacks and theory that it's actually a Version of PTSD
When part of the trip was not processed properly and then stored in maladaptive part , like traumatic memory. I found this very insightful and wan to dive deeper.
https://podcasts.google.com/feed/aHR0cHM6Ly9wbGFudG1lZGljaW5lcG9kY2FzdC5saWJzeW4uY29tL3Jzcw/episode/ZDY4NmY5MDctMmFiNC00NmNjLWIxNzUtY2RkZjNiYjcxY2M4?ep=14
First I thought -WTF, those are 2 very powerful instruments. why mixng?
Then I remember myself trying to do that with Ketamine long time ago with the idea that it might help me to enter the EMDR season and get rid of the blocks i had, but my experiment was not successful that time.
So how we can mix EMDR with psychedelics?
1. As a preparation session before to get to trauma
2. As a tool to get out from repeating loop happening during psychedelic therapy (research in going on in this area)
3. As a better way to use neuroplasticity window after psychedelic to run even better integration
4. Microdosing to enhance EMDR
What are the combinations
1. EMDR + weed to increase body connection
2. EMDR + MDMA - perfect match
3. EMDR + Ketamine - there is a research that it's actually make sense in low doses (maybe I need to try again)
4. EMDR + Classic Psychedelic - great too to process and integrate all insights clothes to the end of trip
P.S. there was a short conversation on flashbacks and theory that it's actually a Version of PTSD
When part of the trip was not processed properly and then stored in maladaptive part , like traumatic memory. I found this very insightful and wan to dive deeper.
https://podcasts.google.com/feed/aHR0cHM6Ly9wbGFudG1lZGljaW5lcG9kY2FzdC5saWJzeW4uY29tL3Jzcw/episode/ZDY4NmY5MDctMmFiNC00NmNjLWIxNzUtY2RkZjNiYjcxY2M4?ep=14
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Psychedelic digest January 2024
Let's try new format, since I've been out of this reality ( well, I was actually testing a bunch of altered states of consciousness with Psychedelics, Breathwork, Soundhealing, Nidra and others, and still processing it )😊
Here is the digest of most interesting Psychedelic news in Jan 2024 from Business, Clinical and Research areas.
Business & Government
Following the approved psychedelics provision,l and 10m$ in funding the Department of Defense (DoD) must create, within 180 days of the enactment, a process for service members with post-traumatic stress disorder (PTSD) or traumatic brain injury (TBI) to participate in clinical trials with psilocybin, MDMA, ibogaine or 5-MeO-DMT.
https://www.benzinga.com/markets/cannabis/23/12/36386091/president-biden-approves-psychedelics-clinical-trials-for-active-military-members
Development and Clinical trials
1. MindMed, a biotech company specializing in psychedelic-inspired medicines, has revealed promising results from its MM-120 drug candidate in the treatment of Generalized Anxiety Disorder (GAD).
The trial highlight that the drug candidate, particularly at the 100 µg dose, demonstrated effectiveness, significantly reducing anxiety symptoms.
https://www.medicalnewstoday.com/articles/lsd-effective-treating-anxiety-clinical-trial
2. Cybin Announces Positive Topline Data from Phase 1 Studies of Proprietary Deuterated DMT Molecules CYB004 and SPL028
Importantly, these are the first-in-human studies of deuterated DMT in healthy participants. both the IV and IM administrations produced robust psychedelic effects and were safe and well-tolerated
Results support progression to a Phase 2 study in Q1 2024
https://financialpost.com/pmn/business-wire-news-releases-pmn/cybin-announces-positive-topline-data-from-phase-1-studies-of-proprietary-deuterated-dmt-molecules-cyb004-and-spl028
Science and Research
And now, the favorite part. For this month I've picked something less usual as we regularly see. Less common psychedelics (Ibogaine), less common sickness (/brain injury) and my favorite, less common way to search for a new drugs( AI).
1. Psychedelics for acquired brain injury (ABI): a review of molecular mechanisms and therapeutic potential
Paper explores the neurochemical properties of psychedelics as a therapeutic intervention for ABI, with a focus on serotonin receptors, sigma-1 receptors, and neurotrophic signalling associated with neuroprotection, neuroplasticity, and neuroinflammation. The promotion of neuronal growth, cell survival, and anti-inflammatory properties exhibited by psychedelics strongly supports their potential benefit in managing ABI.
https://www.nature.com/articles/s41380-023-02360-0
2. Ibogaine for Traumatic brain injury
TBI is a leading cause of injury-related disability worldwide and is likely to remain so until at least 2030. It is also the signature injury of US veterans from recent military conflicts, most often caused by blast exposure.
The prespecified primary outcome was a change in the World Health Organization Disability Assessment Schedule 2.0 from baseline to posttreatment.
https://www.nature.com/articles/s41591-023-02705-w
3. Alphaphold AI discovered new psychedelics
Researchers have used the protein-structure-prediction tool AlphaFold to identify hundreds of thousands of potential new psychedelic molecules — which could help to develop new kinds of antidepressant.
They then synthesized hundreds of the most promising compounds identified with either the predicted and experimental structures and measured their activity in the lab.
The screens with predicted and experimental structures yielded completely different drug candidates.
But to the team’s surprise, the ‘hit rates’ — the proportion of flagged compounds that actually altered protein activity in a meaningful way — were nearly identical for the two groups. And AlphaFold structures identified the drugs that activated the serotonin receptor most potently.
https://www.nature.com/articles/d41586-024-00130-8
Let's try new format, since I've been out of this reality ( well, I was actually testing a bunch of altered states of consciousness with Psychedelics, Breathwork, Soundhealing, Nidra and others, and still processing it )😊
Here is the digest of most interesting Psychedelic news in Jan 2024 from Business, Clinical and Research areas.
Business & Government
Following the approved psychedelics provision,l and 10m$ in funding the Department of Defense (DoD) must create, within 180 days of the enactment, a process for service members with post-traumatic stress disorder (PTSD) or traumatic brain injury (TBI) to participate in clinical trials with psilocybin, MDMA, ibogaine or 5-MeO-DMT.
https://www.benzinga.com/markets/cannabis/23/12/36386091/president-biden-approves-psychedelics-clinical-trials-for-active-military-members
Development and Clinical trials
1. MindMed, a biotech company specializing in psychedelic-inspired medicines, has revealed promising results from its MM-120 drug candidate in the treatment of Generalized Anxiety Disorder (GAD).
The trial highlight that the drug candidate, particularly at the 100 µg dose, demonstrated effectiveness, significantly reducing anxiety symptoms.
https://www.medicalnewstoday.com/articles/lsd-effective-treating-anxiety-clinical-trial
2. Cybin Announces Positive Topline Data from Phase 1 Studies of Proprietary Deuterated DMT Molecules CYB004 and SPL028
Importantly, these are the first-in-human studies of deuterated DMT in healthy participants. both the IV and IM administrations produced robust psychedelic effects and were safe and well-tolerated
Results support progression to a Phase 2 study in Q1 2024
https://financialpost.com/pmn/business-wire-news-releases-pmn/cybin-announces-positive-topline-data-from-phase-1-studies-of-proprietary-deuterated-dmt-molecules-cyb004-and-spl028
Science and Research
And now, the favorite part. For this month I've picked something less usual as we regularly see. Less common psychedelics (Ibogaine), less common sickness (/brain injury) and my favorite, less common way to search for a new drugs( AI).
1. Psychedelics for acquired brain injury (ABI): a review of molecular mechanisms and therapeutic potential
Paper explores the neurochemical properties of psychedelics as a therapeutic intervention for ABI, with a focus on serotonin receptors, sigma-1 receptors, and neurotrophic signalling associated with neuroprotection, neuroplasticity, and neuroinflammation. The promotion of neuronal growth, cell survival, and anti-inflammatory properties exhibited by psychedelics strongly supports their potential benefit in managing ABI.
https://www.nature.com/articles/s41380-023-02360-0
2. Ibogaine for Traumatic brain injury
TBI is a leading cause of injury-related disability worldwide and is likely to remain so until at least 2030. It is also the signature injury of US veterans from recent military conflicts, most often caused by blast exposure.
The prespecified primary outcome was a change in the World Health Organization Disability Assessment Schedule 2.0 from baseline to posttreatment.
https://www.nature.com/articles/s41591-023-02705-w
3. Alphaphold AI discovered new psychedelics
Researchers have used the protein-structure-prediction tool AlphaFold to identify hundreds of thousands of potential new psychedelic molecules — which could help to develop new kinds of antidepressant.
They then synthesized hundreds of the most promising compounds identified with either the predicted and experimental structures and measured their activity in the lab.
The screens with predicted and experimental structures yielded completely different drug candidates.
But to the team’s surprise, the ‘hit rates’ — the proportion of flagged compounds that actually altered protein activity in a meaningful way — were nearly identical for the two groups. And AlphaFold structures identified the drugs that activated the serotonin receptor most potently.
https://www.nature.com/articles/d41586-024-00130-8
Benzinga
In A Historic Move, U.S. Servicemembers Will Legally Access The Groundbreaking Therapies
President Biden officially signed into law the 2024 National Defense Authorization Act (NDAA), large-scale legislation that also contains a mandate to fund clinical trials with psychedelics for active service members.
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HPPD or hallucinogen persisting perception disorder.
Just recently though if there are any good studies on this "flashbacks" phenomenon and here they are:
"One of the most notable findings was the correlation between first-time psychedelic use and an increase in unusual visual experiences. Participants who had never before used psychedelics but did so during the study period reported a greater increase in these experiences than individuals who had used psychedelics previously. This suggests that naivety to psychedelics may predispose individuals to more pronounced visual disturbances, highlighting a potential area of concern for first-time users
https://www.psypost.org/2024/02/psychedelic-use-linked-to-increased-risk-of-unusual-visual-experiences-221224
Just recently though if there are any good studies on this "flashbacks" phenomenon and here they are:
"One of the most notable findings was the correlation between first-time psychedelic use and an increase in unusual visual experiences. Participants who had never before used psychedelics but did so during the study period reported a greater increase in these experiences than individuals who had used psychedelics previously. This suggests that naivety to psychedelics may predispose individuals to more pronounced visual disturbances, highlighting a potential area of concern for first-time users
https://www.psypost.org/2024/02/psychedelic-use-linked-to-increased-risk-of-unusual-visual-experiences-221224
PsyPost
Psychedelic use linked to increased risk of unusual visual experiences
New research suggests that psychedelics like LSD and psilocybin increase unusual visual phenomena, such as seeing with open eyes patterns or objects that are not actually present.
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Brain organoids breakthrough 😊
"Scientists have created brain “organoids” for years, but there are limitations to the tiny, lab-grown cultures. One of the most frustrating issues is a lack of control over their design, which often limits an organoid’s functionality and use. Although researchers long suspected 3D-printing could offer a solution, the workaround has so far proven difficult and ineffective. A new production breakthrough, however, could solve the longstanding barrier, and one day offer new ways of exploring treatment for diseases such as Parkinson’s and Alzeheimer’s."
And we will be finally able to test psychedelics on organoids 😊
https://www.popsci.com/science/3d-printed-brain-tissue/
"Scientists have created brain “organoids” for years, but there are limitations to the tiny, lab-grown cultures. One of the most frustrating issues is a lack of control over their design, which often limits an organoid’s functionality and use. Although researchers long suspected 3D-printing could offer a solution, the workaround has so far proven difficult and ineffective. A new production breakthrough, however, could solve the longstanding barrier, and one day offer new ways of exploring treatment for diseases such as Parkinson’s and Alzeheimer’s."
And we will be finally able to test psychedelics on organoids 😊
https://www.popsci.com/science/3d-printed-brain-tissue/
Popular Science
Scientists have 3D bioprinted functioning human brain tissue
A new method for assembling neuron cultures horizontally instead of vertically helps solve for a longstanding issue.
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Psychedelics and Sex ❤️
14th February is close, plan your plans accordingly 😘
These are the findings of the first known scientific investigation into the effects of psychedelics on sex by Imperial College London. questionnaire responses from almost 300 people before and after a psychedelic experience.
By combining responses from two groups – people taking psychedelics for recreational or wellness/ceremonial purposes, as well as a small group from a clinical trial assessing psylocibin (the compound found in magic mushrooms) for depression – they were able to investigate how the experience influenced a range of aspects relating to sexual functioning.
The analysis reveals that on average, people reported improvements across a range of areas of sexual function up to six months after their psychedelic experience, including their enjoyment of sex, sexual arousal, satisfaction with sex, attraction to partner, their own physical appearance, communication, and their sense of connection.
https://www.imperial.ac.uk/news/251313/psychedelic-experiences-linked-with-improved-sexual/
14th February is close, plan your plans accordingly 😘
These are the findings of the first known scientific investigation into the effects of psychedelics on sex by Imperial College London. questionnaire responses from almost 300 people before and after a psychedelic experience.
By combining responses from two groups – people taking psychedelics for recreational or wellness/ceremonial purposes, as well as a small group from a clinical trial assessing psylocibin (the compound found in magic mushrooms) for depression – they were able to investigate how the experience influenced a range of aspects relating to sexual functioning.
The analysis reveals that on average, people reported improvements across a range of areas of sexual function up to six months after their psychedelic experience, including their enjoyment of sex, sexual arousal, satisfaction with sex, attraction to partner, their own physical appearance, communication, and their sense of connection.
https://www.imperial.ac.uk/news/251313/psychedelic-experiences-linked-with-improved-sexual/
Imperial College London
Psychedelic experiences linked with improved sexual function
Magic mushrooms, LSD and other psychoactive compounds may help to improve sexual function for months after the psychedelic experience.
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Introducing Unlimited Science
One more psychedelic research entity to follow in addition to QRI, John Hopkins and Imperial College of London.
https://unlimitedsciences.org/blog/
One more psychedelic research entity to follow in addition to QRI, John Hopkins and Imperial College of London.
https://unlimitedsciences.org/blog/
Unlimited Sciences
Blog - Unlimited Sciences
Read the Unlimited Sciences blog for updates, FAQs, insights, and stories on psychedelic science, culture, and community.
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Sovereign funds looking to invest in Psychedelics 🥳
January was the second-highest month on record for funding of the psychedelics sector
Groups seeking to harness mind-altering substances including MDMA, psilocybin mushrooms, pictured at right, and 5-MeO-DMT raised at least $163mn across five deals in January
Sovereign wealth funds Temasek and Mubadala in talks to fund biotech groups harnessing mind-altering substances!
This is huge 😎
https://www.ft.com/content/4a2e856c-4736-4b8b-9323-583bb1dbe8f4
January was the second-highest month on record for funding of the psychedelics sector
Groups seeking to harness mind-altering substances including MDMA, psilocybin mushrooms, pictured at right, and 5-MeO-DMT raised at least $163mn across five deals in January
Sovereign wealth funds Temasek and Mubadala in talks to fund biotech groups harnessing mind-altering substances!
This is huge 😎
https://www.ft.com/content/4a2e856c-4736-4b8b-9323-583bb1dbe8f4
Ft
Investors pile into psychedelic drug start-ups tackling mental health
Sovereign wealth funds Temasek and Mubadala in talks to fund biotech groups harnessing mind-altering substances
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DMT research must be legal 👊
"The reality that we experience, waking reality is marely a fraction of consciousness states that exist and if we prevent ourselves from studying those altered states of consciousness we will never have a complete understanding of the universe."
https://youtu.be/LFnCwXPjSCk?si=sqchEfYs4p1B1Omn
"The reality that we experience, waking reality is marely a fraction of consciousness states that exist and if we prevent ourselves from studying those altered states of consciousness we will never have a complete understanding of the universe."
https://youtu.be/LFnCwXPjSCk?si=sqchEfYs4p1B1Omn
YouTube
DMT and the Psychedelic Renaissance | Nick Glynos | TEDxUofM
NOTE FROM TED: Research around psychedelics remains an emerging field of study. TEDx events are independently organized by volunteers. The guidelines we give organizers are described in more detail here: http://storage.ted.com/tedx/manuals/tedx_content_guidelines.pdf…
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LSD, Homosexuality, WW2, Mk ultra, Weekend's history reading
"Tripping on Utopia: Margaret Mead, the Cold War, and the Troubled Birth of Psychedelic Science"
Looks like a new amazing book about psychedelics.😀
Margaret Mead was among the most famous scientists of the 20th century. Despite this, however, her role in the early history of psychedelic research has gone strangely unnoticed.
In this excerpt from my new book Tripping on Utopia, Margaret Mead, recently returned from months of anthropological fieldwork studying an apocalyptic religious movement known as the Noise on the remote island of Manus, becomes involved in the early LSD experiments of Harold Alexander Abramson—and begins planning to take the drug herself.
Mead’s most important source for information about psychedelics at this time was Dr. Harold Abramson, an allergist and expert in “psychosomatic” illnesses. Among other things, Abramson had shared with her the results of an LSD trial that resulted in what he called “loss of fear of homosexuality”: a woman racked by anxiety over her suspicion that she might be a lesbian had, under the drug, resolved her fears. Mead, who was in a committed, yearslong relationship with fellow anthropologist Rhoda Métraux by this time, absorbed this information with great interest. Perhaps LSD could speed up the rate at which global culture adapted to rapid change. Perhaps, as she wrote to herself in June 1954, the drug could be a “short cut” for pulling society “away from mysticism and escape.”
https://slate.com/news-and-politics/2024/02/tripping-on-utopia-book-lsd-psychedelics-history.html
"Tripping on Utopia: Margaret Mead, the Cold War, and the Troubled Birth of Psychedelic Science"
Looks like a new amazing book about psychedelics.😀
Margaret Mead was among the most famous scientists of the 20th century. Despite this, however, her role in the early history of psychedelic research has gone strangely unnoticed.
In this excerpt from my new book Tripping on Utopia, Margaret Mead, recently returned from months of anthropological fieldwork studying an apocalyptic religious movement known as the Noise on the remote island of Manus, becomes involved in the early LSD experiments of Harold Alexander Abramson—and begins planning to take the drug herself.
Mead’s most important source for information about psychedelics at this time was Dr. Harold Abramson, an allergist and expert in “psychosomatic” illnesses. Among other things, Abramson had shared with her the results of an LSD trial that resulted in what he called “loss of fear of homosexuality”: a woman racked by anxiety over her suspicion that she might be a lesbian had, under the drug, resolved her fears. Mead, who was in a committed, yearslong relationship with fellow anthropologist Rhoda Métraux by this time, absorbed this information with great interest. Perhaps LSD could speed up the rate at which global culture adapted to rapid change. Perhaps, as she wrote to herself in June 1954, the drug could be a “short cut” for pulling society “away from mysticism and escape.”
https://slate.com/news-and-politics/2024/02/tripping-on-utopia-book-lsd-psychedelics-history.html
Slate Magazine
One of Our Most Respected 20th-Century Scientists Was LSD-Curious. What Happened?
A document in her papers in the Library of Congress sheds new light on postwar research on psychedelics.
Psychedelic facilitator requirements 😎
In the wake of psychedelic legalization in Colorado, a state board is outlining proposed training requirements for psychedelic "facilitators."
36 pages PDF is attached
https://www.9news.com/article/news/health/colorado-releases-proposed-rules-for-psychedelic-therapy-guides/73-4febfab5-e298-46fb-9f28-bd6768eb86c9
In the wake of psychedelic legalization in Colorado, a state board is outlining proposed training requirements for psychedelic "facilitators."
36 pages PDF is attached
https://www.9news.com/article/news/health/colorado-releases-proposed-rules-for-psychedelic-therapy-guides/73-4febfab5-e298-46fb-9f28-bd6768eb86c9
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MAPS-Integration-Workbook.pdf
1.2 MB
Psychedelic integration guide 🔥
MAPS just released a new Psychedelics Integration guide. So far it's probably the best document in this area.
MAPS just released a new Psychedelics Integration guide. So far it's probably the best document in this area.
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Indigenous Psilocilybin history 🍄
Weekend reading:
The most comprehensive research on indigenous Psilocilybin use
An annotated bibliography in: Journal of Psychedelic Studies
https://akjournals.com/view/journals/2054/aop/article-10.1556-2054.2023.00297/article-10.1556-2054.2023.00297.xml
Weekend reading:
The most comprehensive research on indigenous Psilocilybin use
An annotated bibliography in: Journal of Psychedelic Studies
https://akjournals.com/view/journals/2054/aop/article-10.1556-2054.2023.00297/article-10.1556-2054.2023.00297.xml
AKJournals
Indigenous psilocybin mushroom practices: An annotated bibliography
Abstract This annotated bibliography comprises 49 texts concerning psilocybin mushroom practices developed by Indigenous peoples. The books and articles have been selected for their academic rigor, relevance, and historical significance, and to foreground…
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Have Anxiety? Take LSD🤪
LSD now officially and efficiently can help with anxiety with only 100ug dose. What do I think? Hmmm. Yes, god damn it, we already know it 😂.
Some history facts:
2013 breakthrough FDA for Ketamine
2017 breakthrough FDA for MDMA
2018 breakthrough FDA for Psilocybin
2024 breakthrough FDA for LSD 😎<- we are here
"breakthrough designation is a recognition that a drug has demonstrated evidence of clinical efficacy in meeting an unmet medical need with morbidity and mortality associated with it,”
MindMed plans to hold an End-of-Phase 2 meeting with the U.S. Food & Drug Administration (FDA) in the first half of 2024 and initiate its Phase 3 clinical program in the second half of 2024
https://www.businesswire.com/news/home/20240307733599/en/
LSD now officially and efficiently can help with anxiety with only 100ug dose. What do I think? Hmmm. Yes, god damn it, we already know it 😂.
Some history facts:
2013 breakthrough FDA for Ketamine
2017 breakthrough FDA for MDMA
2018 breakthrough FDA for Psilocybin
2024 breakthrough FDA for LSD 😎<- we are here
"breakthrough designation is a recognition that a drug has demonstrated evidence of clinical efficacy in meeting an unmet medical need with morbidity and mortality associated with it,”
MindMed plans to hold an End-of-Phase 2 meeting with the U.S. Food & Drug Administration (FDA) in the first half of 2024 and initiate its Phase 3 clinical program in the second half of 2024
https://www.businesswire.com/news/home/20240307733599/en/
BusinessWire
MindMed Receives FDA Breakthrough Therapy Designation and Announces Positive 12-Week Durability Data From Phase 2B Study of MM120…
Mind Medicine (MindMed) Inc. (NASDAQ: MNMD), (Cboe Canada MMED), (the “Company” or “MindMed”), a clinical stage biopharmaceutical company developing n
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New research on LSD Microdosing
Let it be the week of LSD 🤪
It was found that 26 micrograms of LSD increased brain complexity by about 12 percent compared to a placebo, without altering consciousness.
The trials were repeated in two further groups, one with moderate (7.5 mg) and high (15 mg) doses of tetrahydrocannabinol (THC) from cannabis and one with medical methamphetamine at doses of 10 mg and 20 mg. In these experiments, THC, but not methamphetamine, affected consciousness at high doses.
The team's analysis of all the trials found only the 26-microgram dose of LSD had a significant effect on neural complexity, increasing it by approximately 12 percent on average when compared to the placebo"
I've personally found 50 micrigram dose very effective for a variety of things from self-healing and meditation to sex and learning new skills. However i tried this microdosing size of approximately 20 mcg just few times and it's definitely a big room for exploring the best application for such dose.
Will soon write some guides on LSD mini-dosing 😁
https://www.sciencealert.com/tiny-doses-of-lsd-boost-unique-signals-in-the-human-brain
Let it be the week of LSD 🤪
It was found that 26 micrograms of LSD increased brain complexity by about 12 percent compared to a placebo, without altering consciousness.
The trials were repeated in two further groups, one with moderate (7.5 mg) and high (15 mg) doses of tetrahydrocannabinol (THC) from cannabis and one with medical methamphetamine at doses of 10 mg and 20 mg. In these experiments, THC, but not methamphetamine, affected consciousness at high doses.
The team's analysis of all the trials found only the 26-microgram dose of LSD had a significant effect on neural complexity, increasing it by approximately 12 percent on average when compared to the placebo"
I've personally found 50 micrigram dose very effective for a variety of things from self-healing and meditation to sex and learning new skills. However i tried this microdosing size of approximately 20 mcg just few times and it's definitely a big room for exploring the best application for such dose.
Will soon write some guides on LSD mini-dosing 😁
https://www.sciencealert.com/tiny-doses-of-lsd-boost-unique-signals-in-the-human-brain
ScienceAlert
Tiny Doses of LSD Boost Unique Signals in The Human Brain
The hidden benefits of microdosing.
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Hipsters win. Well at least for now.
Mushroom Extract Outperforms Synthetic Psilocybin in Psychiatric Therapy - Neuroscience News
https://neurosciencenews.com/psilocybin-mental-health-25739/
Mushroom Extract Outperforms Synthetic Psilocybin in Psychiatric Therapy - Neuroscience News
https://neurosciencenews.com/psilocybin-mental-health-25739/
Neuroscience News
Mushroom Extract Outperforms Synthetic Psilocybin in Psychiatric Therapy
A new study reveals that psilocybin-containing mushroom extract exhibits a more potent and enduring effect on synaptic plasticity compared to its synthetic counterpart.
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150m$ for Mushrooms startup 🙃
Cybin Announces Closing of the Oversubscribed Private Placement of U.S. $150 Million
The net proceeds of the Private Placement are expected to be used for certain Phase 3 drug development activities for CYB003, working capital and general corporate purposes. CYB003, is a proprietary deuterated psilocybin analog in development for the potential treatment of Major Depressive Disorder ("MDD"). If approved by the U.S. Food and Drug Administration (the "FDA"), CYB003 would be the first known adjunctive psychedelic-based therapeutic for the treatment of MDD.
https://finance.yahoo.com/news/cybin-announces-closing-oversubscribed-private-155300089.html
Cybin Announces Closing of the Oversubscribed Private Placement of U.S. $150 Million
The net proceeds of the Private Placement are expected to be used for certain Phase 3 drug development activities for CYB003, working capital and general corporate purposes. CYB003, is a proprietary deuterated psilocybin analog in development for the potential treatment of Major Depressive Disorder ("MDD"). If approved by the U.S. Food and Drug Administration (the "FDA"), CYB003 would be the first known adjunctive psychedelic-based therapeutic for the treatment of MDD.
https://finance.yahoo.com/news/cybin-announces-closing-oversubscribed-private-155300089.html
Yahoo Finance
Cybin Announces Closing of the Oversubscribed Private Placement of U.S. $150 Million
TORONTO, March 19, 2024--Cybin Inc. (NYSE American:CYBN) (Cboe CA:CYBN) ("Cybin" or the "Company"), a clinical-stage biopharmaceutical company committed to revolutionizing mental healthcare by developing new and innovative next-generation psychedelic-based…
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How I ate 40g of Mushrooms or measuring shrooms dose.
Actually this new research on measuring Psilocilybin in mushrooms is quite important. I've recently eaten 40gramms of some mushrooms which were offered to me as one dose.
I was a bit shocked as usually it should be 10-20 times less for one dose. But as a curious researcher I gave it a try 😅.
As you can see I'm still here and alive, though I had some conversations with entities 🙃. But subjustively it was similar to one dose.
So back to the research:
New technique measures psilocybin potency of mushrooms
Using liquid chromatography with tandem mass spectrometry, Schug and colleagues were able to extract and measure the strength of the mushrooms.
https://phys.org/news/2024-03-technique-psilocybin-potency-mushrooms.html
Actually this new research on measuring Psilocilybin in mushrooms is quite important. I've recently eaten 40gramms of some mushrooms which were offered to me as one dose.
I was a bit shocked as usually it should be 10-20 times less for one dose. But as a curious researcher I gave it a try 😅.
As you can see I'm still here and alive, though I had some conversations with entities 🙃. But subjustively it was similar to one dose.
So back to the research:
New technique measures psilocybin potency of mushrooms
Using liquid chromatography with tandem mass spectrometry, Schug and colleagues were able to extract and measure the strength of the mushrooms.
https://phys.org/news/2024-03-technique-psilocybin-potency-mushrooms.html
phys.org
New technique measures psilocybin potency of mushrooms
Since the 1970s, the federal government has listed the active ingredients in mushrooms—psilocybin and psilocin—as illegal and having no accepted medical use.
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Psychedelic digest march 2024.
Sorry, sorry I spent a month in Ubud and barely had time to post on a daily basis,but I carefully read all important news and here are the top ones for you and it's not a joke 🤣
Top important psychedelic news from Market, Research, Religion, Education, Industry, Investment and Government.
# Top Psychedelic Religion news
First Church in USA in the way to "legalize" the use of Ayahuasca
https://www.chronline.com/stories/psychedelic-washington-church-working-toward-legal-immunity-to-consume-ayahuasca,335768?
# Top Psychedelics Education
Minor degree in Psychedelics opened in University of Boulder
https://www.9news.com/video/news/education/naropa-university-boulder-minor-psychedelics-mushrooms/73-5c670769-61a4-4ab3-8e49-0bd1aa584474
As well is in Naropa university! Wow! Two programs in one month
https://finance.yahoo.com/news/naropa-university-launches-pioneering-psychedelic-113400650.html
How to check quickly what is true and what is bullshit in Psychedelics
https://www.psychologytoday.com/us/blog/being-awake-better/202403/8-ways-to-learn-about-psychedelics
#Top psychedelic clinical trials
Psyched's intranasal 5-MEO-DMT passed phase 2 for Threatmen resident depression 😊
https://www.pharmabiz.com/NewsDetails.aspx?aid=168226&sid=2
#TOP Government psychedelic actions
https://www.marijuanamoment.net/u-s-company-offers-free-psychedelics-training-services-to-ukraine-health-professionals-to-treat-trauma-from-war-with-russia/
Fluence - a psychedelic Startup together with
Ukrainian Psychedelic Research Association (UPRA) and the U.S. nonprofit Heal Ukraine Trauma (HUT), is providing free training materials for psychologists and medical doctors who are interested in incorporation psychedelics into their practices.
Unlike medical cannabis, psychedelics have not been legalized in Ukraine. Even so, more than 540 mental health professionals have already signed up for the program, Fluence said.
# Top Psychedelic Patent news
https://finance.yahoo.com/news/breakthrough-wellness-clearmind-medicines-psychedelic-115500300.html
Psychedelic Patent in China, that's interesting.
MEAI is a new psychoactive molecule that reduces desire to consume alcoholic beverages and exerts a slight euphoric, alcohol-like experience with potential to change the lives of millions who struggle to drink in moderation. Clearmind’s MEAI-based flagship treatment focuses on Alcohol Use Disorder, which is incredibly common.
# Top Psychedelic Market news
MOXY - new kid in Psychedelic renaissance
Mindstate Design Labs uses AI to find the best candidate for psychedelic assistant therapy.
Mindstate Design Labs has submitted its first IND, asking the FDA to greenlight a clinical trial for its lead asset targeting 5-MeO-MiPT, also known as moxy, a psychedelic selected from more than 70,000 “trip reports” to classify states of consciousness
Using large language models and natural language processing, Mindstate has built a platform that segments experiences by drug or psychedelic receptors. In some cases, the platform can visualize an experience, like color transformations
https://www.fiercebiotech.com/biotech/mindstates-first-ai-derived-psychedelic-heads-clinic
Sorry, sorry I spent a month in Ubud and barely had time to post on a daily basis,but I carefully read all important news and here are the top ones for you and it's not a joke 🤣
Top important psychedelic news from Market, Research, Religion, Education, Industry, Investment and Government.
# Top Psychedelic Religion news
First Church in USA in the way to "legalize" the use of Ayahuasca
https://www.chronline.com/stories/psychedelic-washington-church-working-toward-legal-immunity-to-consume-ayahuasca,335768?
# Top Psychedelics Education
Minor degree in Psychedelics opened in University of Boulder
https://www.9news.com/video/news/education/naropa-university-boulder-minor-psychedelics-mushrooms/73-5c670769-61a4-4ab3-8e49-0bd1aa584474
As well is in Naropa university! Wow! Two programs in one month
https://finance.yahoo.com/news/naropa-university-launches-pioneering-psychedelic-113400650.html
How to check quickly what is true and what is bullshit in Psychedelics
https://www.psychologytoday.com/us/blog/being-awake-better/202403/8-ways-to-learn-about-psychedelics
#Top psychedelic clinical trials
Psyched's intranasal 5-MEO-DMT passed phase 2 for Threatmen resident depression 😊
https://www.pharmabiz.com/NewsDetails.aspx?aid=168226&sid=2
#TOP Government psychedelic actions
https://www.marijuanamoment.net/u-s-company-offers-free-psychedelics-training-services-to-ukraine-health-professionals-to-treat-trauma-from-war-with-russia/
Fluence - a psychedelic Startup together with
Ukrainian Psychedelic Research Association (UPRA) and the U.S. nonprofit Heal Ukraine Trauma (HUT), is providing free training materials for psychologists and medical doctors who are interested in incorporation psychedelics into their practices.
Unlike medical cannabis, psychedelics have not been legalized in Ukraine. Even so, more than 540 mental health professionals have already signed up for the program, Fluence said.
# Top Psychedelic Patent news
https://finance.yahoo.com/news/breakthrough-wellness-clearmind-medicines-psychedelic-115500300.html
Psychedelic Patent in China, that's interesting.
MEAI is a new psychoactive molecule that reduces desire to consume alcoholic beverages and exerts a slight euphoric, alcohol-like experience with potential to change the lives of millions who struggle to drink in moderation. Clearmind’s MEAI-based flagship treatment focuses on Alcohol Use Disorder, which is incredibly common.
# Top Psychedelic Market news
MOXY - new kid in Psychedelic renaissance
Mindstate Design Labs uses AI to find the best candidate for psychedelic assistant therapy.
Mindstate Design Labs has submitted its first IND, asking the FDA to greenlight a clinical trial for its lead asset targeting 5-MeO-MiPT, also known as moxy, a psychedelic selected from more than 70,000 “trip reports” to classify states of consciousness
Using large language models and natural language processing, Mindstate has built a platform that segments experiences by drug or psychedelic receptors. In some cases, the platform can visualize an experience, like color transformations
https://www.fiercebiotech.com/biotech/mindstates-first-ai-derived-psychedelic-heads-clinic
Psychedelic Washington church working toward legal immunity to consume ayahuasca - The Daily Chronicle
As early as this spring, the federal government could allow members of a Spokane religious congregation to lay on the grassy floor of a nondenoscript building to consume their sacrament — a …
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