Bad trip? Here is the solution 😁
Harry Shapiro, director of Drugwise, emphasizes the significant potential of psychedelics as psychotherapeutic tools, especially when traditional antidepressants fail. However, the power of these hallucinogenic compounds cannot be underestimated, and there's always a risk of a "bad trip." Symptoms of a bad trip can range from panic, depression, confusion, to intense hallucinations. To mitigate these risks:
Preparation is Key: Ensure the right dose, set (internal mindset), and setting (external environment). The right music can also enhance the experience.
Handling a Bad Trip: If things go south, don't panic. Remember it's temporary. Communicate with a trusted individual or seek professional help if needed.
Transforming a Bad Trip: From a shamanic perspective, challenging experiences are part of the journey and can lead to profound insights and growth.
Understanding Bad Trips: They can occur unpredictably, much like life's ups and downs. The focus should be on deriving meaning from them.
https://www.dazeddigital.com/life-culture/article/60641/1/how-to-make-the-best-of-a-bad-psychedelic-trip-acid-mushrooms
Harry Shapiro, director of Drugwise, emphasizes the significant potential of psychedelics as psychotherapeutic tools, especially when traditional antidepressants fail. However, the power of these hallucinogenic compounds cannot be underestimated, and there's always a risk of a "bad trip." Symptoms of a bad trip can range from panic, depression, confusion, to intense hallucinations. To mitigate these risks:
Preparation is Key: Ensure the right dose, set (internal mindset), and setting (external environment). The right music can also enhance the experience.
Handling a Bad Trip: If things go south, don't panic. Remember it's temporary. Communicate with a trusted individual or seek professional help if needed.
Transforming a Bad Trip: From a shamanic perspective, challenging experiences are part of the journey and can lead to profound insights and growth.
Understanding Bad Trips: They can occur unpredictably, much like life's ups and downs. The focus should be on deriving meaning from them.
https://www.dazeddigital.com/life-culture/article/60641/1/how-to-make-the-best-of-a-bad-psychedelic-trip-acid-mushrooms
Dazed
How to make the best of a bad psychedelic trip
It’s normal to feel nervous about having a tough time on psychedelics – here’s how you can prepare yourself if things get too much
😁2
UC Berkeley free psychedelic course🔥
Dive into the mesmerizing world of psychedelics with UC Berkeley's Professor David Presti!
From the neurobiology of LSD to the cultural significance of Ayahuasca, this course offers a comprehensive exploration for both beginners and experts.
What a time 😅
https://www.edx.org/learn/science/university-of-california-berkeley-psychedelics-and-the-mind
Dive into the mesmerizing world of psychedelics with UC Berkeley's Professor David Presti!
From the neurobiology of LSD to the cultural significance of Ayahuasca, this course offers a comprehensive exploration for both beginners and experts.
What a time 😅
https://www.edx.org/learn/science/university-of-california-berkeley-psychedelics-and-the-mind
edX
BerkeleyX: Psychedelics and the Mind | edX
UC Berkeley Professor David Presti skillfully navigates the science, culture, and history of psychedelics for both the novice learner and the curious expert interested in fact-based learning surrounding visionary substances.
❤2
Practical Psychedelic Mixology 🤡
List of polysubstance combinations - Wikipedia
Surprised that there is no name for Cannabis+Ketamine as I believe it's definitely something interesting happenings there. 🙊
https://en.wikipedia.org/wiki/List_of_polysubstance_combinations
List of polysubstance combinations - Wikipedia
Surprised that there is no name for Cannabis+Ketamine as I believe it's definitely something interesting happenings there. 🙊
https://en.wikipedia.org/wiki/List_of_polysubstance_combinations
Unlearning in AI and EMDR: Conceptual Parallels and Distinctions
The technique described by Microsoft researchers to make AI "forget" copyrighted material, conceptually intriguing. The method bears a resemblance to the therapeutic approach of EMDR, a recognized treatment for trauma.
Conceptual Similarities:
Targeted Erasure: Just as the researchers aim to erase specific knowledge (e.g., Harry Potter content) from the AI model, EMDR targets specific traumatic memories in patients, aiming to desensitize their emotional charge.
Fine-tuning: The AI technique involves fine-tuning the model to effectively erase specific content. Similarly, EMDR involves a structured eight-phase approach, where the therapist fine-tunes the process based on the patient's responses.
Adaptability: The AI's ability to adapt and "unlearn" mirrors the brain's plasticity, where neural pathways can be restructured, especially when traumatic memories are reprocessed in EMDR.
Differences:
Mechanism: While the AI technique employs a three-part method involving training on target data, replacing unique expressions, and fine-tuning on alternative predictions, EMDR uses bilateral stimulation (often in the form of guided eye movements) to help patients process traumatic memories.
Objective: The primary goal for AI is to ensure copyright compliance and adaptability. In contrast, EMDR aims to alleviate distress from traumatic memories and promote psychological healing.
Complexity: Human emotions and memories are multifaceted, with deep-rooted connections to various life experiences. AI models, although complex, operate on data and algorithms without the emotional depth inherent in human cognition.
In conclusion, while the conceptual framework of "unlearning" or "forgetting" is present in both the AI technique and EMDR, the underlying mechanisms, objectives, and complexities differ. It's fascinating to observe how principles of neuroscience and psychology can find echoes in the realm of artificial intelligence.
https://venturebeat.com/ai/researchers-turn-to-harry-potter-to-make-ai-forget-about-copyright-material/
The technique described by Microsoft researchers to make AI "forget" copyrighted material, conceptually intriguing. The method bears a resemblance to the therapeutic approach of EMDR, a recognized treatment for trauma.
Conceptual Similarities:
Targeted Erasure: Just as the researchers aim to erase specific knowledge (e.g., Harry Potter content) from the AI model, EMDR targets specific traumatic memories in patients, aiming to desensitize their emotional charge.
Fine-tuning: The AI technique involves fine-tuning the model to effectively erase specific content. Similarly, EMDR involves a structured eight-phase approach, where the therapist fine-tunes the process based on the patient's responses.
Adaptability: The AI's ability to adapt and "unlearn" mirrors the brain's plasticity, where neural pathways can be restructured, especially when traumatic memories are reprocessed in EMDR.
Differences:
Mechanism: While the AI technique employs a three-part method involving training on target data, replacing unique expressions, and fine-tuning on alternative predictions, EMDR uses bilateral stimulation (often in the form of guided eye movements) to help patients process traumatic memories.
Objective: The primary goal for AI is to ensure copyright compliance and adaptability. In contrast, EMDR aims to alleviate distress from traumatic memories and promote psychological healing.
Complexity: Human emotions and memories are multifaceted, with deep-rooted connections to various life experiences. AI models, although complex, operate on data and algorithms without the emotional depth inherent in human cognition.
In conclusion, while the conceptual framework of "unlearning" or "forgetting" is present in both the AI technique and EMDR, the underlying mechanisms, objectives, and complexities differ. It's fascinating to observe how principles of neuroscience and psychology can find echoes in the realm of artificial intelligence.
https://venturebeat.com/ai/researchers-turn-to-harry-potter-to-make-ai-forget-about-copyright-material/
VentureBeat
Researchers turn to Harry Potter to make AI forget about copyrighted material
Their unlearning technique may also be more effective for fictional texts than non-fiction, since fictional worlds contain more unique...
🤔1
“If anything, ibogaine is the hardest psychedelic to work with. But I’m here for the challenge.” - Deborah C. Mash
1. Ibogaine is a very promising psychedelic especially for curind opioid addiction. Fentanyl zombies, etc 😅
2. Ibogaine has a much harder path to FDA
3. VR is a great tool to configure set and setting while administering ibogaine in hospital (also valid for a Ketamine btw)
P.S. Great documentary to watch: NIGHT AND LIGHT: THE STORY OF IBOGA AND IBOGAINE
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5saWJzeW4uY29tLzgxODk1L3Jzcw/episode/ZmE2NDc2YjctYmI3Mi00ZmM4LTkyZTktYzc0OTQwMTNlOTdh?ep=14
1. Ibogaine is a very promising psychedelic especially for curind opioid addiction. Fentanyl zombies, etc 😅
2. Ibogaine has a much harder path to FDA
3. VR is a great tool to configure set and setting while administering ibogaine in hospital (also valid for a Ketamine btw)
P.S. Great documentary to watch: NIGHT AND LIGHT: THE STORY OF IBOGA AND IBOGAINE
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5saWJzeW4uY29tLzgxODk1L3Jzcw/episode/ZmE2NDc2YjctYmI3Mi00ZmM4LTkyZTktYzc0OTQwMTNlOTdh?ep=14
❤3
What if DMT entities are actually mind/conchesness viruses that we are only able to detect by running our brain in "disassembler mode" using DMT.
😁3
Thousands of programmable DNA-cutters found in algae, snails, and other organisms
Bye bye CRISPR , hello Fanzors🤟
https://phys.org/news/2023-10-thousands-programmable-dna-cutters-algae-snails.html
Bye bye CRISPR , hello Fanzors🤟
https://phys.org/news/2023-10-thousands-programmable-dna-cutters-algae-snails.html
phys.org
Thousands of programmable DNA-cutters found in algae, snails, and other organisms
A diverse set of species, from snails to algae to amoebas, make programmable DNA-cutting enzymes called Fanzors—and a new study from scientists at MIT's McGovern Institute for Brain Research has identified ...
Ex–Tesla director gives Harvard $16 million to study psychedelics
https://qz.com/a-former-tesla-director-is-giving-harvard-16-million-t-1850932713
https://qz.com/a-former-tesla-director-is-giving-harvard-16-million-t-1850932713
Quartz
A former Tesla director is giving Harvard $16 million to study psychedelics in society and culture
Antonio Gracias' funding will enable the university to look beyond therapeutic uses for the drugs
🔥2
MDMA and critical periods.
"They hired me to learn autism in humans and I decided to give MDMA to octopuses 😅" - Gul Dolen. MD, pH. D.
1. Octopuses are super adaptive which means that their critical periods are like always on. Or can be turned on and off by some mechanisms and it's super important to learn it as it may help with humans .
2. People have critical periods for different systems when those systems are open to learning more.
One of the most knowm ones are language learning
But there is a theory that social interactions also have critical periods ( like I suppose usually from puberty till 20-ish )
3. Tested on mice . Waited for 48 hours , measured ability to learn from social environment. And adults started to learn from social environment. (Reopening of critical periods)
But! If mices don't have social interaction during a session they tend to not reopen those critical periods!
So. sychedelics are the "universal magic key" to re-open those critical periods but again, set and setting is vital
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5saWJzeW4uY29tLzgxODk1L3Jzcw/episode/MGU3ZDc0NTYtOWExMS00MjJjLWFjZjEtZTA4YTUxMWNmMTFk?ep=14
"They hired me to learn autism in humans and I decided to give MDMA to octopuses 😅" - Gul Dolen. MD, pH. D.
1. Octopuses are super adaptive which means that their critical periods are like always on. Or can be turned on and off by some mechanisms and it's super important to learn it as it may help with humans .
2. People have critical periods for different systems when those systems are open to learning more.
One of the most knowm ones are language learning
But there is a theory that social interactions also have critical periods ( like I suppose usually from puberty till 20-ish )
3. Tested on mice . Waited for 48 hours , measured ability to learn from social environment. And adults started to learn from social environment. (Reopening of critical periods)
But! If mices don't have social interaction during a session they tend to not reopen those critical periods!
So. sychedelics are the "universal magic key" to re-open those critical periods but again, set and setting is vital
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5saWJzeW4uY29tLzgxODk1L3Jzcw/episode/MGU3ZDc0NTYtOWExMS00MjJjLWFjZjEtZTA4YTUxMWNmMTFk?ep=14
❤1
Great discussion on latest MDMA assistant therapy results
1. MDMA - assisted therapy FDA approval is clother and closther
2. novasupport.org - great initiative to support victims of Nova festival
3. We all hope that Israel Psychedelic conference will happen on December as planned 🙏
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5saWJzeW4uY29tLzgxODk1L3Jzcw/episode/MDJiZWExNGUtM2FmOC00MWQ2LThhOTMtOGU3NjZjMDk5M2E3?ep=14
1. MDMA - assisted therapy FDA approval is clother and closther
2. novasupport.org - great initiative to support victims of Nova festival
3. We all hope that Israel Psychedelic conference will happen on December as planned 🙏
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5saWJzeW4uY29tLzgxODk1L3Jzcw/episode/MDJiZWExNGUtM2FmOC00MWQ2LThhOTMtOGU3NjZjMDk5M2E3?ep=14
❤1
A new must read in Psychedelics books.
"For Ten Trips, I took 10 different substances in 10 different contexts: DMT in a neuro-imaging research trial, magic mushrooms on a therapist’s couch, ayahuasca on the altar of a psychedelic church, LSD on the roundabout of a dual carriageway, mescaline half-way up Half-Dome, iboga at a plant-based retreat centre in the Bahamas, vaporised toad venom in some forest above Silicon Valley, and eventually, inexorably, to the indigenous cultures of Mexico, Peru and Columbia that have used the medicines for aeons: as someone sagely told me, with psychedelics, all roads eventually lead South."
https://www.esquire.com/uk/life/fitness-wellbeing/a45204988/why-i-wrote-a-first-hand-guide-to-the-new-age-of-psychedelics/
"For Ten Trips, I took 10 different substances in 10 different contexts: DMT in a neuro-imaging research trial, magic mushrooms on a therapist’s couch, ayahuasca on the altar of a psychedelic church, LSD on the roundabout of a dual carriageway, mescaline half-way up Half-Dome, iboga at a plant-based retreat centre in the Bahamas, vaporised toad venom in some forest above Silicon Valley, and eventually, inexorably, to the indigenous cultures of Mexico, Peru and Columbia that have used the medicines for aeons: as someone sagely told me, with psychedelics, all roads eventually lead South."
https://www.esquire.com/uk/life/fitness-wellbeing/a45204988/why-i-wrote-a-first-hand-guide-to-the-new-age-of-psychedelics/
Esquire
Why I Wrote a (First-Hand) Guide to the New Age of Psychedelics
In his new book, ‘Ten Trips', clinical neuroscientist Andy Mitchell takes on the ever-evolving industry around psychoactive drugs, and explains why Michael Pollan’s seminal book is ready for an update
https://www.goodnewsnetwork.org/psychedelic-drugs-may-be-able-to-treat-brain-injuries-stimulating-new-neurons-to-replace-impaired-ones/
"Rats slowly infused with low doses of DMT after a stroke had fewer damaged tissues and more extensive recovery,” wrote National Geographic.
"Rats slowly infused with low doses of DMT after a stroke had fewer damaged tissues and more extensive recovery,” wrote National Geographic.
Good News Network
Psychedelic Drugs May Be Able to Treat Brain Injuries, Stimulating New Neurons to Replace Impaired Ones
The idea is that psychedelics could keep the critical windows open long enough to recover far more function than would otherwise be the case.
🔥1
Shrooms in VR ? Yes , now officially make sense.
"Findings published this week in Frontiers in Psychiatry indicate the 20 subjects who took part in the small trial at Pacific Neuroscience Institute’s Treatment & Research In Psychedelics Center – known as TRIP –overall were calmer and better able to ease into psilocybin-assisted therapy when they participated in the nature-themed immersive video experience during their treatment. "
https://smdp.com/2023/09/22/immersive-nature-videos-may-enhance-psychedelic-assisted-therapy-for-alcohol-addiction/
"Findings published this week in Frontiers in Psychiatry indicate the 20 subjects who took part in the small trial at Pacific Neuroscience Institute’s Treatment & Research In Psychedelics Center – known as TRIP –overall were calmer and better able to ease into psilocybin-assisted therapy when they participated in the nature-themed immersive video experience during their treatment. "
https://smdp.com/2023/09/22/immersive-nature-videos-may-enhance-psychedelic-assisted-therapy-for-alcohol-addiction/
Santa Monica Daily Press
Immersive nature videos may enhance psychedelic-assisted therapy for alcohol addiction
In a fascinating marriage of art and science, researchers at Providence Saint John’s Health Center have found that a dose
All we need is a Ketamine tonight.
It's the second podcast on the Ketamine-assisted therapy which makes me think that it's the best tool for adapting to changes, be it either some negative or extreme experiences like relocation or miss of relatives ( what was discussed in the previous one) as well as for positive changes like Accelerated growth, which was discussed in this episode.
I personally see a big future for Ketamine and those two podcasts are a great prove.
https://podcasts.google.com/feed/aHR0cHM6Ly9wbGFudG1lZGljaW5lcG9kY2FzdC5saWJzeW4uY29tL3Jzcw/episode/ZmFjMTg1ZjgtMGZkMS00MDcyLWI0YzAtYzk3MWQ4YjMxZWI3?ep=14
It's the second podcast on the Ketamine-assisted therapy which makes me think that it's the best tool for adapting to changes, be it either some negative or extreme experiences like relocation or miss of relatives ( what was discussed in the previous one) as well as for positive changes like Accelerated growth, which was discussed in this episode.
I personally see a big future for Ketamine and those two podcasts are a great prove.
https://podcasts.google.com/feed/aHR0cHM6Ly9wbGFudG1lZGljaW5lcG9kY2FzdC5saWJzeW4uY29tL3Jzcw/episode/ZmFjMTg1ZjgtMGZkMS00MDcyLWI0YzAtYzk3MWQ4YjMxZWI3?ep=14
⚡2
There is much better way to consume Ketamine.
"Psycheceutical’s patented NeuroDirect ketamine topical delivery system that is designed to target free nerve ending at the back of the neck. As such, the company believes that psychedelic medicine is delivered safely and effectively without hallucinogenic effects."
https://www.biopharma-reporter.com/Article/2023/09/26/Psycheceutical-Q-A-Could-topical-ketamine-transform-PTSD-treatment
"Psycheceutical’s patented NeuroDirect ketamine topical delivery system that is designed to target free nerve ending at the back of the neck. As such, the company believes that psychedelic medicine is delivered safely and effectively without hallucinogenic effects."
https://www.biopharma-reporter.com/Article/2023/09/26/Psycheceutical-Q-A-Could-topical-ketamine-transform-PTSD-treatment
biopharma-reporter.com
Psycheceutical Q&A: Could topical ketamine transform PTSD treatment?
Psychedelics have re-emerged in the world of medicine as promising treatments for various mental health conditions, particularly post-traumatic stress disorder (PTSD).
❤1
Scientists Find Cannabis Compound Inside Totally Different Plant : ScienceAlert
Neto said chemical analysis had found "Trema" contains CBD but not THC, raising the possibility of an abundant new source of the former – one that would not face the legal and regulatory hurdles of cannabis, which continues to be outlawed in many places, including Brazil.
https://www.sciencealert.com/scientists-find-cannabis-compound-inside-totally-different-plant
Neto said chemical analysis had found "Trema" contains CBD but not THC, raising the possibility of an abundant new source of the former – one that would not face the legal and regulatory hurdles of cannabis, which continues to be outlawed in many places, including Brazil.
https://www.sciencealert.com/scientists-find-cannabis-compound-inside-totally-different-plant
ScienceAlert
Scientists Find Cannabis Compound Inside Totally Different Plant
Hiding in plain sight!
Israel Psychedelic scene is growing 💥
https://allisrael.com/israeli-start-up-researches-use-of-psychedelics-to-treat-severe-pain-waits-for-fda-approval?__cf_chl_tk=XsdParILUIC3utjxr8vH4FE6nz5Gc8fnZcgeOhYmTUM-1697891741-0-gaNycGzNDNA
"Unlike other tech companies, Dreazen says the company is pursuing combining technology with an unconventional source: A Colorado River frog that secretes the substance 5-MeO-DMT from its gland, a naturally occurring tryptamine recognized for its psychedelic properties."
I hope they will aso provide a better way to consume it cuz those pipes are it's annoying 😂
https://allisrael.com/israeli-start-up-researches-use-of-psychedelics-to-treat-severe-pain-waits-for-fda-approval?__cf_chl_tk=XsdParILUIC3utjxr8vH4FE6nz5Gc8fnZcgeOhYmTUM-1697891741-0-gaNycGzNDNA
"Unlike other tech companies, Dreazen says the company is pursuing combining technology with an unconventional source: A Colorado River frog that secretes the substance 5-MeO-DMT from its gland, a naturally occurring tryptamine recognized for its psychedelic properties."
I hope they will aso provide a better way to consume it cuz those pipes are it's annoying 😂
All Israel News
Israeli start-up researches use of psychedelics to treat severe pain, waits for FDA approval
'Psychedelic substances are not addictive, but they still pose risks,' says CEO
New MDMA book review 😀
Rachel Nuwer’s I Feel Love: MDMA and the Quest for Connection in a Fractured World is clearly aimed at a broad audience. It will resonate with readers who have experienced MDMA recreationally, probably at a rave, or therapeutically, probably to heal the emotional aftereffects of deep-seated trauma. Or both. But it’s also intended for readers who have never touched the drug, colloquially known as ecstasy or molly. Perhaps it’s especially for them.
https://science.thewire.in/the-sciences/book-review-the-long-strange-history-of-mdma/
Rachel Nuwer’s I Feel Love: MDMA and the Quest for Connection in a Fractured World is clearly aimed at a broad audience. It will resonate with readers who have experienced MDMA recreationally, probably at a rave, or therapeutically, probably to heal the emotional aftereffects of deep-seated trauma. Or both. But it’s also intended for readers who have never touched the drug, colloquially known as ecstasy or molly. Perhaps it’s especially for them.
https://science.thewire.in/the-sciences/book-review-the-long-strange-history-of-mdma/
science.thewire.in
Book Review: The Long, Strange History of MDMA
In 'I Feel Love', Rachel Nuwer shows how MDMA has grown from a party drug into a potentially valuable therapeutic tool.
❤4
Nice MDMA therapy video for newbies.
"Psychedelics to the brain are like a microscope for biology"
https://youtu.be/A3TvqMwgEco?si=AnO_m-ZEWjLgABki
"Psychedelics to the brain are like a microscope for biology"
https://youtu.be/A3TvqMwgEco?si=AnO_m-ZEWjLgABki
YouTube
Psychedelics could heal your trauma, says neuroscientist Rachel Yehuda
“Traumatic experiences are here to stay, and we shouldn’t view them as a prison.” Professor of Neuroscience Rachel Yehuda on how psychedelics may help liberate us from our post-traumatic stress.
Subscribe to Big Think on YouTube ► https://www.youtube.…
Subscribe to Big Think on YouTube ► https://www.youtube.…
❤1
Ibogaine + 5MEO = SolderFlip 💥
Wow, two most potent psychedelics together! I bet this shit can cure even zombies 🤡
The treatment included a combination of ibogaine hydrochloride, derived from the West African shrub iboga, and 5-MeO-DMT, a psychedelic substance secreted by the Colorado River toad
War time, war news, heh.
Each Special Ops veteran received a single oral ibogaine hydrochloride dose and, on a separate day, at least three incremental inhalation doses adding up to 50 milligrams of 5-MeO-DMT, also commonly called Five or Bufo. Preparation and reflection sessions preceded and followed each treatment.
https://news.osu.edu/psychedelics-improve-mental-health-cognition-in-special-ops-veterans/
Wow, two most potent psychedelics together! I bet this shit can cure even zombies 🤡
The treatment included a combination of ibogaine hydrochloride, derived from the West African shrub iboga, and 5-MeO-DMT, a psychedelic substance secreted by the Colorado River toad
War time, war news, heh.
Each Special Ops veteran received a single oral ibogaine hydrochloride dose and, on a separate day, at least three incremental inhalation doses adding up to 50 milligrams of 5-MeO-DMT, also commonly called Five or Bufo. Preparation and reflection sessions preceded and followed each treatment.
https://news.osu.edu/psychedelics-improve-mental-health-cognition-in-special-ops-veterans/
Ohio State News
Psychedelics improve mental health, cognition in special ops veterans
Chart review reports effects of 2-drug treatment at Mexico clinic
❤3